YRC Public Data Repository - Protein Structure Prediction

Protein:	RLF2
Organism:	Saccharomyces cerevisiae
Length:	606 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RLF2.

Description	E-value	Query Range	Subject Range
RLF2 - Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles ... gi\|207340408 - gi\|207340408\|gb\|EDZ68769.1\| YPR018Wp-like protein [Saccharomyces cerevisiae AWRI1631] RLF2_YEAST - Chromatin assembly factor 1 subunit p90 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=... gi\|151942807 - gi\|151942807\|gb\|EDN61153.1\| chromatin assembly factor-I (CAF-I) p90 subunit [Saccharomyces cerevisia... gi\|190407962 - gi\|190407962\|gb\|EDV11227.1\| chromatin assembly factor-I p90 subunit [Saccharomyces cerevisiae RM11-1...	2.0E-84	[1..606]	[1..606]
gi\|3668187 - gi\|3668187\|dbj\|BAA33452.1\| myosin heavy chain [Theragra chalcogramma]	2.0E-54	[5..362]	[916..1274]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1	2.0E-46	[5..416]	[916..1328]
MYH1_HORSE - Myosin-1 OS=Equus caballus GN=MYH1 PE=2 SV=1	4.0E-46	[5..416]	[917..1329]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1	5.0E-46	[5..435]	[919..1347]
gi\|42476190, gi\|... - gi\|42476190\|ref\|NP_060004.2\| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens], gi\|...	8.0E-46	[5..435]	[920..1348]
gi\|14250231, gi\|... - ref\|NP_659210.1\| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi\|14250231\|gb...	1.0E-45	[5..471]	[921..1384]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQHLKSIPL QDDTKKKGIL SFFQNTTTVK SNKFLTKEKD VITLDDPKED VSGPMIETVK  60
   61 QETMKSINKE CADEMKTTPK KANAEDKLLC YKNSPIQSTK YDRNTNKQVP NGNIIAIETK 120
  121 SRSSSPCSKR ELSSSKKEEA KREKELKKQQ RAEEKHRKEL LRQEEKKKKE LKVEEERQRR 180
  181 AELKKQKEEE KRRKEEARLE AKRRKEEERL KKEEEIRLKE EAKERAQSRI GNFFKKLSDS 240
  241 NTPVVEKSDY EKFFLPFYAK DGVR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [265-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSNKWKLTKV ELEGSKRKID DELLNSKDKT SSDDLLNWLQ SRRLPRGHKI KRKAVDVLQQ  60
   61 MPLKEKTDDE LQSLLAQVPH KYIKFYENVR PPFIGTYSMD FTLPPNDPFS TKGTGFNYDY 120
  121 DSDVEWVNEE EEGEVDNLES GEEEEEEEDD EDVPSEGEFD GFLDSEENSD LDGLPCAKRK 180
  181 FVGPLIPTIC LKSNFENLSE ENKRYLQQLK AEVIIETDG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [484-606]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIDPFKEPKT SSLPSKRSNS DLQAQTASQS QSPEKKQKAM ITDPMDLLRL FDGVQDSTFS  60
   61 LGTVTEIAQK NLPQYNKQTI KNTIKEYAIR SSGKGDLPRK WVIKDAQNWE NLRANANMPT 120
  121 PSL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [418-514]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSEGEFDGFL DSEENSDLDG LPCAKRKFVG PLIPTICLKS NFENLSEENK RYLQQLKAEV  60
   61 IIETDGPIDP FKEPKTSSLP SKRSNSDLQA QTASQSQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [515-606]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPEKKQKAMI TDPMDLLRLF DGVQDSTFSL GTVTEIAQKN LPQYNKQTIK NTIKEYAIRS  60
   61 SGKGDLPRKW VIKDAQNWEN LRANANMPTP SL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits