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View Structure Prediction Details

Protein: GYP5
Organism: Saccharomyces cerevisiae
Length: 894 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GYP5.

Description E-value Query
Range
Subject
Range
gi|114593160 - gi|114593160|ref|XP_526514.2| PREDICTED: TBC1 domain family, member 14 [Pan troglodytes]
443.0 [0..1] [707..124]

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Predicted Domain #1
Region A:
Residues: [1-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDKSIEKN TDTIASEVHE GDNHSNNLGS MEEEIKSTPS DQYEEIAIIP TEPLHSDKEL  60
   61 NDKQQSLGHE APTNVSREEP IGISGDEDTQ ITEQNVNEQR QETREPSSEI DLNEPLDVEK 120
  121 DVTTDVQAPN GLNIEKEYDA VKENEKVYAD TKEVVSSPEN REVTGKNSGG EKSSSSKFLD 180
  181 DESGTTTAAN ANDISISSEV TPERSSENDN NQIHITNEVA AGINLNENKE QKAAIEDGPV 240
  241 TAENLSSETA RKVPPIPTQI INEKGDNSSE NEVSAIPTTS SPPLPPRQNV ATSTSPKLPP 300
  301 RGKQREQPPK TKNAVPPPLE EEMKSEKFRK NFEETKRNSY HHVPLTGSKT AQLESTAEIN 360
  361 LIASRYRKTS HHLNKEGEET RESLQEGQSF LKSTFTSFLE NLSEYNEVEN VN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [413-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDREMFKID WSFWTQVVND YATVASNEPE NLEAHVTNGI PPQIRGIIWQ LMANSKSREM  60
   61 EDIYETLLDT ECLHEATIRR DLRRTKFVAE DKMESLYKVI KVYSVYDPDV GYTQGMGFIA 120
  121 APLLINCENE AESFGLLVGL MKNYGLRELF LPGMPGLMLM LYQFDRLLEE HSPSLYNRLI 180
  181 REGISSTMYA TQWFLTFFAY KFPLEFVLRI FDIVFVEGIE VLLKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.221849
Match: 1fkmA_
Description: Ypt/Rab-GAP domain of gyp1p
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [638-813]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVNLMLKNEE TLVKLRFDEL LDFLKDELFN YYLMGNQDDA SVVQMGLSNG NSFKGNDDGT  60
   61 FSYNVDLFVH DAMTGVYITP LTLRRYRGEY VEIHEKEQKK EDHYESLRIQ NHQLQREAQK 120
  121 LEHDYSILNK ENISAANELI QNRLNMEMLL DEKNDLINTI TDIKSQIEEE IRKQNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [814-894]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPDASLPKA DLREDLERTI SRNNEVMREN GQLEERITEL QAEIDELINI NKEQVSTASL  60
   61 LERDSKAKGR KGWTGFKKVF K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle