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View Structure Prediction Details

Protein: HSP82
Organism: Saccharomyces cerevisiae
Length: 709 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSP82.

Description E-value Query
Range		 Subject
Range
HS90B_CHICK - Heat shock cognate protein HSP 90-beta OS=Gallus gallus GN=HSP90AB1 PE=2 SV=1
 0.0 [2..709] [11..725]
HS90A_BOVIN - Heat shock protein HSP 90-alpha OS=Bos taurus GN=HSP90AA1 PE=1 SV=3
gi|115503919 - gi|115503919|gb|ABI99473.1| heat shock protein alpha [Ovis aries]
 0.0 [2..709] [16..733]
gi|194027 - gi|194027|gb|AAA37866.1| heat-shock protein hsp84
 0.0 [2..709] [11..724]
gi|168277956, gi... - gi|168277956|dbj|BAG10956.1| heat shock protein HSP 90-beta [synthetic construct], gi|123999414|gb|A...
HSP90AB1 - heat shock protein 90kDa alpha (cytosolic), class B member 1
 0.0 [2..709] [11..724]
HS90A_PIG - Heat shock protein HSP 90-alpha OS=Sus scrofa GN=HSP90AA1 PE=2 SV=3
 0.0 [2..709] [16..733]
HS90B_BRARE, HS9... - (O57521) Heat shock protein HSP 90-beta, (O57521) Heat shock protein HSP 90-beta
 0.0 [2..709] [10..725]

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Predicted Domain #1
Region A:
Residues: [1-219] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASETFEFQA EITQLMSLII NTVYSNKEIF LRELISNASD ALDKIRYKSL SDPKQLETEP  60
   61 DLFIRITPKP EQKVLEIRDS GIGMTKAELI NNLGTIAKSG TKAFMEALSA GADVSMIGQF 120
  121 GVGFYSLFLV ADRVQVISKS NDDEQYIWES NAGGSFTVTL DEVNERIGRG TILRLFLKDD 180
  181 QLEYLEEKRI KEVIKRHSEF VAYPIQLVVT KEVEKEVPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1236.39794
Match: 1a4h__
Description: HSP90
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [220-709] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEEEKKDEEK KDEEKKDEDD KKPKLEEVDE EEEKKPKTKK VKEEVQEIEE LNKTKPLWTR  60
   61 NPSDITQEEY NAFYKSISND WEDPLYVKHF SVEGQLEFRA ILFIPKRAPF DLFESKKKKN 120
  121 NIKLYVRRVF ITDEAEDLIP EWLSFVKGVV DSEDLPLNLS REMLQQNKIM KVIRKNIVKK 180
  181 LIEAFNEIAE DSEQFEKFYS AFSKNIKLGV HEDTQNRAAL AKLLRYNSTK SVDELTSLTD 240
  241 YVTRMPEHQK NIYYITGESL KAVEKSPFLD ALKAKNFEVL FLTDPIDEYA FTQLKEFEGK 300
  301 TLVDITKDFE LEETDEEKAE REKEIKEYEP LTKALKEILG DQVEKVVVSY KLLDAPAAIR 360
  361 TGQFGWSANM ERIMKAQALR DSSMSSYMSS KKTFEISPKS PIIKELKKRV DEGGAQDKTV 420
  421 KDLTKLLYET ALLTSGFSLD EPTSFASRIN RLISLGLNID EDEETETAPE ASTAAPVEEV 480
  481 PADTEMEEVD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 1000.0
Match: PF00183
Description: Hsp90 protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle