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View Structure Prediction Details

Protein: AFT2
Organism: Saccharomyces cerevisiae
Length: 416 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AFT2.

Description E-value Query
Range
Subject
Range
gi|840881 - gi|840881|emb|CAA54586.1| RCS1 [Saccharomyces cerevisiae]
400.0 [0..38] [285..95]
gi|45198432, gi|... - gi|45198432|ref|NP_985461.1| AFL087Cp [Ashbya gossypii ATCC 10895], gi|44984319|gb|AAS53285.1| AFL08...
gi|44984319 - gi|44984319|gb|AAS53285.1| AFL087Cp [Ashbya gossypii ATCC 10895]
265.0 [0..37] [317..75]
gi|49526254 - gi|49526254|emb|CAG59878.1| unnamed protein product [Candida glabrata]
gi|49526254, gi|... - gi|50289031|ref|XP_446945.1| unnamed protein product [Candida glabrata], gi|49526254|emb|CAG59878.1|...
251.0 [0..38] [214..2]
gi|49642345 - gi|49642345|emb|CAH00307.1| KLLA0D03256p [Kluyveromyces lactis]
gi|50306475, gi|... - gi|50306475|ref|XP_453211.1| unnamed protein product [Kluyveromyces lactis], gi|49642345|emb|CAH0030...
164.0 [0..98] [350..218]
gi|50425555, gi|... - gi|50425555|ref|XP_461373.1| hypothetical protein DEHA0F25124g [Debaryomyces hansenii CBS767], gi|49...
88.0 [0..51] [137..21]
orf19.2272, orf1... - orf19.2272 CGDID:CAL0006340 Assembly 19, Contig19-10143 (76320, 73924) CDS, reverse complemented, tr...
AFT2_CANAL - Iron-regulated transcriptional activator AFT2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN...
69.0 [0..51] [135..21]

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Predicted Domain #1
Region A:
Residues: [1-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAKSMKSII SVPISVSKTG KMKLTASPDN LASMMSKDQN KLIHLDPVPS FEDRHEIKPW  60
   61 LQKIFYPQGI DIVIERSDSS KVTFKCRSVR SKVGLNPKSK GSSSRSHACP FRIRAAYSVR 120
  121 LQKWNVVVMN NIHSHELRFD LITKTDDYKK FKENLRQKND EKAIKTFDEL EYKASLNLPL 180
  181 VTPIISCDCG LTKEIEAFNN IFLPLSNPPL TSKKNLLKTN KNSVSKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [228-303]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSRQMDNSKP RPRLKTKLDA DLHDTGFLDN FKTRNSCVKI EKEDSLTNLN EIDFTNMFCN  60
   61 DNFIQNYNQG LMELLT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.532 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.505 N/A N/A d.58.17 Metal-binding domain
View Download 0.473 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.473 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.337 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.329 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.262 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.247 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.234 N/A N/A c.47.1 Thioredoxin-like

Predicted Domain #3
Region A:
Residues: [304-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPTPGPSSSS CILPSTPTRP LSQSKMDIAL SESTTSSPNF METDAPYGDE IIKVSKDTKS  60
   61 NAPTADTDIA TNLGKERNEN FGMLNYNYEA LLHFNDEHFN ELNSIDPALI SKY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.242 a.118.22 Description not found.
View Download 0.242 a.118.1 ARM repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle