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View Structure Prediction Details

Protein: NIP100
Organism: Saccharomyces cerevisiae
Length: 868 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIP100.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
0.0 [42..814] [859..1618]
MYH2_HORSE - Myosin-2 OS=Equus caballus GN=MYH2 PE=2 SV=1
0.0 [35..814] [852..1618]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
0.0 [35..814] [855..1621]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
0.0 [42..850] [862..1656]
gi|42476190, gi|... - gi|42476190|ref|NP_060004.2| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens], gi|...
0.0 [35..814] [856..1622]

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Predicted Domain #1
Region A:
Residues: [1-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNAGVQVDT NMQKISLQDT VLVNEMKGRV KFIGETQFAK GIWYGIELDK PLGKNDGSAN  60
   61 GIRYFDIDLK KANSNGGYYG LFCKKDTLQF YKPDDDEHSL LNGNAAQETI KNLQVKCESL 120
  121 ASKLNKIKIE NHELKTSVEK LSTNETVLLS KISRLDKLVK ELKVENGNMK THLDNFNHLL 180
  181 DASDSVMAPD LDKGTLLERS HLLQGLLDQT KLSYDKAMKV QEDLLEENTQ LLEENAVLSK 240
  241 KISDLGLQLQ QTNNTIGDLA LQIEAQSKSS NIVDKLTNDN ILLTSNIKAL NNELEELQAK 300
  301 EKLDENLRIT YEQLEQELRL QLSNLQSALE NEKEIAGTYI EE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [343-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSRLKATLES IEAKTSHKFQ SLELKVNTLQ EELYQNKLLK KFYQIYEPFA QPHLAALSSQ  60
   61 LQYLAEVIES ENFGKLENIE IHIILKVLSS ISYALHIYTI KNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.801 0.026 microtubule binding a.60.9 lambda integrase-like, N-terminal domain

Predicted Domain #3
Region A:
Residues: [446-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDHLETTLQC FKVNIAPISM WLSEFLQRKF SSKQETAFSI CQFLEDNKFL DKDVTLILKI  60
   61 LHPILETTVP KLLAFLRTNS NFNDNDTLCL IGSLYERSLS LIARIDKLIG KEEISKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [563-790]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNRLFLYPSC DITLSSILTI LFSDALFLRQ DYKRISSLKK LEVFFQGIES LLENITIFPE  60
   61 QPSQQTSDSE SQCNIKEGNF SNSLLSDRLN EENIRLKEVL VQKENMLTEL ETKIKIIIGR 120
  121 DLERKTLEEN IKTLKVELNN KNEENCGKTE ILNKLKEENF NLVNRLKNME LKLYQIKDNN 180
  181 TLNKIYLDRE KVDRVNLVSE IMELRETIRR QIKEQKRVSI DFSWLDEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [791-868]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAVENKQPFK EHINHSLDTL GIEMFNFVST SRILDLKLDQ PLAEDELWHE RDHSYISYLK  60
   61 RKRKNIRLKS QNVVTYYK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle