YRC Public Data Repository - Protein Structure Prediction

Protein:	FMP30
Organism:	Saccharomyces cerevisiae
Length:	468 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FMP30.

Description	E-value	Query Range	Subject Range
FMP30 - Protein of unknown function proposed to be involved in N-acylethanolamine metabolism; related to hum... gi\|207340582 - gi\|207340582\|gb\|EDZ68889.1\| YPL103Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190407853 - gi\|190407853\|gb\|EDV11118.1\| hypothetical protein SCRG_02392 [Saccharomyces cerevisiae RM11-1a] FMP30_YEAST - N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial OS=Saccharomyces cerevisi...	0.0	[1..468]	[1..468]
gi\|26334279 - gi\|26334279\|dbj\|BAC30857.1\| unnamed protein product [Mus musculus]	5.0E-62	[114..468]	[62..386]
gi\|21241024, gi\|... - gi\|21241024\|ref\|NP_640606.1\| hypothetical protein XAC0250 [Xanthomonas axonopodis pv. citri str. 306...	2.0E-58	[126..468]	[6..326]
gi\|17431596 - gi\|17431596\|emb\|CAD18273.1\| putative zn-dependent hydrolase of the beta-lactamase fold protein [Rals... gi\|17549343 - gi\|17549343\|ref\|NP_522683.1\| hypothetical protein RS05497 [Ralstonia solanacearum GMI1000]	9.0E-57	[142..466]	[26..329]
gi\|14024397, gi\|... - gi\|14024397\|dbj\|BAB51001.1\| mlr4314 [Mesorhizobium loti MAFF303099], gi\|13473647\|ref\|NP_105215.1\| hy...	2.0E-56	[123..466]	[14..343]
gi\|66766587, gi\|... - gi\|66766587\|ref\|YP_241349.1\| hypothetical protein XC_0242 [Xanthomonas campestris pv. campestris str... gi\|21229710, gi\|... - gi\|21229710\|ref\|NP_635627.1\| hypothetical protein XCC0232 [Xanthomonas campestris pv. campestris str...	2.0E-56	[126..467]	[5..324]
gi\|9107142, gi\|1... - gi\|9107142\|gb\|AAF84826.1\|AE004021_3 conserved hypothetical protein [Xylella fastidiosa 9a5c], gi\|158... gi\|11360814 - pir\|\|B82607 conserved hypothetical protein XF2024 [imported] - Xylella fastidiosa (strain 9a5c)	3.0E-56	[130..464]	[5..324]
gi\|254743538 - gi\|254743538\|ref\|ZP_05201223.1\| hypothetical protein BantKB_21462 [Bacillus anthracis str. Kruger B] gi\|254737275 - gi\|254737275\|ref\|ZP_05194979.1\| hypothetical protein BantWNA_19154 [Bacillus anthracis str. Western ... gi\|254722237 - gi\|254722237\|ref\|ZP_05184025.1\| hypothetical protein BantA1_07199 [Bacillus anthracis str. A1055] gi\|254684829 - gi\|254684829\|ref\|ZP_05148689.1\| hypothetical protein BantC_13370 [Bacillus anthracis str. CNEVA-9066... gi\|30256892, gi\|... - gi\|30262261\|ref\|NP_844638.1\| hypothetical protein BA2247 [Bacillus anthracis str. Ames], gi\|30256892... gi\|254759106 - gi\|254759106\|ref\|ZP_05211133.1\| hypothetical protein BantA9_12446 [Bacillus anthracis str. Australia... gi\|254751591 - gi\|254751591\|ref\|ZP_05203628.1\| hypothetical protein BantV_03951 [Bacillus anthracis str. Vollum] gi\|190565413, gi... - gi\|190565413\|ref\|ZP_03018333.1\| conserved hypothetical protein [Bacillus anthracis Tsiankovskii-I], ... gi\|195993516, gi... - gi\|196033836\|ref\|ZP_03101247.1\| conserved hypothetical protein [Bacillus cereus W], gi\|195993516\|gb\|... gi\|170706614, gi... - gi\|170706614\|ref\|ZP_02897073.1\| conserved hypothetical protein [Bacillus anthracis str. A0389], gi\|1... gi\|172084352, gi... - gi\|177649278\|ref\|ZP_02932280.1\| conserved hypothetical protein [Bacillus anthracis str. A0174], gi\|1... gi\|167509974, gi... - gi\|167642071\|ref\|ZP_02400296.1\| conserved hypothetical protein [Bacillus anthracis str. A0193], gi\|1... gi\|49329129, gi\|... - gi\|49477573\|ref\|YP_036361.1\| hypothetical protein BT9727_2032 [Bacillus thuringiensis serovar konkuk... gi\|170669061, gi... - gi\|170687010\|ref\|ZP_02878229.1\| conserved hypothetical protein [Bacillus anthracis str. A0465], gi\|1... gi\|49185103, gi\|... - gi\|49185103\|ref\|YP_028355.1\| hypothetical protein BAS2092 [Bacillus anthracis str. Sterne], gi\|49179... gi\|164713672, gi... - gi\|165870517\|ref\|ZP_02215171.1\| conserved hypothetical protein [Bacillus anthracis str. A0488], gi\|1... gi\|47527545, gi\|... - gi\|47527545\|ref\|YP_018894.1\| hypothetical protein GBAA2247 [Bacillus anthracis str. 'Ames Ancestor']... gi\|167632718, gi... - gi\|167632718\|ref\|ZP_02391044.1\| conserved hypothetical protein [Bacillus anthracis str. A0442], gi\|1... gi\|229268043, gi... - gi\|229603635\|ref\|YP_002866601.1\| hypothetical protein BAA_2310 [Bacillus anthracis str. A0248], gi\|2... gi\|229121802, gi... - gi\|229121802\|ref\|ZP_04251022.1\| Outer membrane protein romA [Bacillus cereus 95/8201], gi\|228661591\|... gi\|228813742, gi... - gi\|228945868\|ref\|ZP_04108211.1\| Outer membrane protein romA [Bacillus thuringiensis serovar monterre... gi\|227814937, gi... - gi\|227814937\|ref\|YP_002814946.1\| hypothetical protein BAMEG_2348 [Bacillus anthracis str. CDC 684], ...	4.0E-56	[155..468]	[5..307]
gi\|28198696, gi\|... - gi\|28198696\|ref\|NP_779010.1\| hypothetical protein PD0791 [Xylella fastidiosa Temecula1], gi\|28056787... gi\|182631496, gi... - gi\|182681386\|ref\|YP_001829546.1\| putative Zn-dependent hydrolase [Xylella fastidiosa M23], gi\|182631...	1.0E-55	[130..463]	[5..323]
gi\|25521108 - pir\|\|G97682 hypothetical protein AGR_C_4888 [imported] - Agrobacterium tumefaciens (strain C58, Cere... gi\|15157909, gi\|... - gi\|15889950\|ref\|NP_355631.1\| hypothetical protein AGR_C_4888 [Agrobacterium tumefaciens str. C58], g...	2.0E-55	[123..466]	[46..374]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFVTCHVQM RLLLQRRLVR LRESELFRPQ TSLSTFKRHA SQKTRPIQKC SRKYARILLL  60
   61 SVLVPYTGYA FYVSLATVKQ IDLRNEMCQR LEENNNEVTY KGSLLKYSPL EVLGRFENPF 120
  121 EEYRIQTVFE FFANRVFELF ERNRGGIPRD VHQMNKLMPV HKPTWGPNLV DVDP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [175-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEETALPLEC KVLDELHIPT AVEENEGSKC PVYNTWLGQS CNYTVYNGLR ILTDPLFSDF  60
   61 LIHKTLGPKR ITQMPSQITE VPKPDIILVS HNHPDHLDLE SLEYWSGKDS PLWIVPKGMK 120
  121 SYMTSNGCDN VLELSWWETL QVKKNNEIYH ISATPAMHWS GRSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.39794
Match:	1smlA_
Description:	Zn metallo-beta-lactamase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.941400907161877	bayes_pls_golite062009
thiolester hydrolase activity	0.155608764594826	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [339-468]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDTNKSLWCS FLLTHHGNPI LFHAGDTGYV KDLFVRIKER FGKGCKLALL PCGQYCPEWH  60
   61 QKPRHINPQE VLKIMKDLEA RNVLGVHWGT FVLSGEYFLE PKEKLEMLAE WGGFKDRCYC 120
  121 PELGKTECFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.39794
Match:	1smlA_
Description:	Zn metallo-beta-lactamase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: