| Protein: | BRO1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 844 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BRO1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..844] | [1..844] |
|
|
1.0E-80 | [4..797] | [8..793] |
|
|
2.0E-78 | [12..726] | [152..869] |
|
|
2.0E-78 | [12..726] | [1141..1858] |
|
Region A: Residues: [1-163] |
1 11 21 31 41 51
| | | | | |
1 MKPYLFDLKL KDTEKLDWKK GLSSYLKKSY GSSQWRTFYD EKATSELDHL RNNANGELAP 60
61 SSLSEQNLKY YSFLEHLYFR LGSKGSRLKM DFTWYDAEYS SAQKGLKYTQ HTLAFEKSCT 120
121 LFNIAVIFTQ IARENINEDY KNSIANLTKA FSCFEYLSEN FLN
|
| Detection Method: |  |
| Confidence: | 66.148742 |
| Match: | PF03097 |
| Description: | BRO1-like domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [164-291] |
1 11 21 31 41 51
| | | | | |
1 SPSVDLQSEN TRFLANICHA EAQELFVLKL LNDQISSKQY TLISKLSRAT CNLFQKCHDF 60
61 MKEIDDDVAI YGEPKWKTTV TCKLHFYKSL SAYYHGLHLE EENRVGEAIA FLDFSMQQLI 120
121 SSLPFKTW
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.964 | 0.009 | vacuolar transport | a.24.3 | Cytochromes |
| View | Download | 0.957 | 0.009 | vacuolar transport | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.967 | 0.009 | vacuolar transport | a.19.1 | Fertilization protein |
| View | Download | 0.965 | 0.009 | vacuolar transport | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.953 | 0.009 | vacuolar transport | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.932 | 0.009 | vacuolar transport | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.902 | 0.009 | vacuolar transport | a.24.3 | Cytochromes |
| View | Download | 0.873 | 0.009 | vacuolar transport | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.864 | 0.009 | vacuolar transport | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.862 | 0.009 | vacuolar transport | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.859 | 0.009 | vacuolar transport | a.47.2 | t-snare proteins |
| View | Download | 0.832 | 0.009 | vacuolar transport | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.795 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.795 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.793 | 0.009 | vacuolar transport | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.787 | 0.009 | vacuolar transport | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.782 | 0.009 | vacuolar transport | a.25.1 | Ferritin-like |
| View | Download | 0.777 | 0.009 | vacuolar transport | a.7.7 | BAG domain |
| View | Download | 0.769 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.768 | 0.009 | vacuolar transport | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.760 | 0.009 | vacuolar transport | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.758 | 0.009 | vacuolar transport | a.47.2 | t-snare proteins |
| View | Download | 0.746 | 0.009 | vacuolar transport | a.24.4 | Hemerythrin |
| View | Download | 0.717 | 0.009 | vacuolar transport | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.714 | 0.009 | vacuolar transport | a.25.1 | Ferritin-like |
| View | Download | 0.712 | 0.009 | vacuolar transport | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.691 | 0.009 | vacuolar transport | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.677 | 0.009 | vacuolar transport | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.644 | 0.009 | vacuolar transport | d.92.2 | beta-N-acetylhexosaminidase-like domain |
| View | Download | 0.630 | 0.009 | vacuolar transport | a.63.1 | Apolipophorin-III |
| View | Download | 0.616 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.595 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.589 | 0.009 | vacuolar transport | a.63.1 | Apolipophorin-III |
| View | Download | 0.558 | 0.009 | vacuolar transport | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.544 | 0.009 | vacuolar transport | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.540 | 0.009 | vacuolar transport | a.7.8 | GAT domain |
| View | Download | 0.532 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.531 | 0.009 | vacuolar transport | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.512 | 0.009 | vacuolar transport | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.498 | 0.009 | vacuolar transport | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.496 | 0.009 | vacuolar transport | a.7.4 | Smac/diablo |
| View | Download | 0.495 | 0.009 | vacuolar transport | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.478 | 0.009 | vacuolar transport | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.477 | 0.009 | vacuolar transport | a.24.3 | Cytochromes |
| View | Download | 0.466 | 0.009 | vacuolar transport | f.21.1 | Transmembrane di-heme cytochromes |
| View | Download | 0.457 | 0.009 | vacuolar transport | a.29.2 | Bromodomain |
| View | Download | 0.445 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.432 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.431 | 0.009 | vacuolar transport | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.430 | 0.009 | vacuolar transport | a.29.2 | Bromodomain |
| View | Download | 0.428 | 0.009 | vacuolar transport | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.412 | 0.009 | vacuolar transport | a.24.1 | Apolipoprotein |
| View | Download | 0.410 | 0.009 | vacuolar transport | a.118.8 | TPR-like |
| View | Download | 0.405 | 0.009 | vacuolar transport | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.400 | 0.009 | vacuolar transport | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.399 | 0.009 | vacuolar transport | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.390 | 0.009 | vacuolar transport | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.389 | 0.009 | vacuolar transport | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.386 | 0.009 | vacuolar transport | a.7.1 | Spectrin repeat |
| View | Download | 0.385 | 0.009 | vacuolar transport | a.46.1 | Methionine synthase domain |
| View | Download | 0.382 | 0.009 | vacuolar transport | a.47.1 | STAT |
| View | Download | 0.379 | 0.009 | vacuolar transport | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.374 | 0.009 | vacuolar transport | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.366 | 0.009 | vacuolar transport | a.47.2 | t-snare proteins |
| View | Download | 0.358 | 0.009 | vacuolar transport | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.357 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.356 | 0.009 | vacuolar transport | a.19.1 | Fertilization protein |
| View | Download | 0.355 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.350 | 0.009 | vacuolar transport | a.7.7 | BAG domain |
| View | Download | 0.344 | 0.009 | vacuolar transport | a.2.5 | Prefoldin |
| View | Download | 0.339 | 0.009 | vacuolar transport | d.95.2 | Homing endonucleases |
| View | Download | 0.334 | 0.009 | vacuolar transport | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.330 | 0.009 | vacuolar transport | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.316 | 0.009 | vacuolar transport | a.75.1 | Ribosomal protein S7 |
| View | Download | 0.314 | 0.009 | vacuolar transport | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.311 | 0.009 | vacuolar transport | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.304 | 0.009 | vacuolar transport | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.299 | 0.009 | vacuolar transport | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.299 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.299 | 0.009 | vacuolar transport | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.298 | 0.009 | vacuolar transport | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.298 | 0.009 | vacuolar transport | a.30.1 | ROP protein |
| View | Download | 0.294 | 0.009 | vacuolar transport | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.293 | 0.009 | vacuolar transport | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.288 | 0.009 | vacuolar transport | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.287 | 0.009 | vacuolar transport | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.284 | 0.009 | vacuolar transport | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.280 | 0.009 | vacuolar transport | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.277 | 0.009 | vacuolar transport | a.22.1 | Histone-fold |
| View | Download | 0.276 | 0.009 | vacuolar transport | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.276 | 0.009 | vacuolar transport | a.182.1 | GatB/YqeY domain |
| View | Download | 0.273 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.270 | 0.009 | vacuolar transport | c.95.1 | Thiolase-like |
| View | Download | 0.265 | 0.009 | vacuolar transport | a.2.5 | Prefoldin |
| View | Download | 0.264 | 0.009 | vacuolar transport | a.22.1 | Histone-fold |
| View | Download | 0.264 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.262 | 0.009 | vacuolar transport | a.79.1 | Antitermination factor NusB |
| View | Download | 0.261 | 0.009 | vacuolar transport | a.74.1 | Cyclin-like |
| View | Download | 0.261 | 0.009 | vacuolar transport | a.2.7 | tRNA-binding arm |
| View | Download | 0.261 | 0.009 | vacuolar transport | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.260 | 0.009 | vacuolar transport | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.259 | 0.009 | vacuolar transport | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.259 | 0.009 | vacuolar transport | a.2.7 | tRNA-binding arm |
| View | Download | 0.257 | 0.009 | vacuolar transport | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.253 | 0.009 | vacuolar transport | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.251 | 0.009 | vacuolar transport | a.39.1 | EF-hand |
| View | Download | 0.250 | 0.009 | vacuolar transport | e.20.1 | Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment |
| View | Download | 0.248 | 0.009 | vacuolar transport | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.248 | 0.009 | vacuolar transport | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.246 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.246 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.243 | 0.009 | vacuolar transport | a.48.2 | Transferrin receptor ectodomain, C-terminal domain |
| View | Download | 0.241 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.239 | 0.009 | vacuolar transport | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.238 | 0.009 | vacuolar transport | c.44.1 | Phosphotyrosine protein phosphatases I |
| View | Download | 0.237 | 0.009 | vacuolar transport | a.2.7 | tRNA-binding arm |
| View | Download | 0.232 | 0.009 | vacuolar transport | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.231 | 0.009 | vacuolar transport | c.8.5 | GroEL apical domain-like |
| View | Download | 0.228 | 0.009 | vacuolar transport | a.22.1 | Histone-fold |
| View | Download | 0.228 | 0.009 | vacuolar transport | a.1.1 | Globin-like |
| View | Download | 0.227 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.227 | 0.009 | vacuolar transport | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.226 | 0.009 | vacuolar transport | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.226 | 0.009 | vacuolar transport | a.1.1 | Globin-like |
| View | Download | 0.226 | 0.009 | vacuolar transport | f.21.1 | Transmembrane di-heme cytochromes |
| View | Download | 0.225 | 0.009 | vacuolar transport | d.95.2 | Homing endonucleases |
| View | Download | 0.225 | 0.009 | vacuolar transport | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.220 | 0.009 | vacuolar transport | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.220 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.217 | 0.009 | vacuolar transport | a.118.1 | ARM repeat |
| View | Download | 0.209 | 0.009 | vacuolar transport | a.26.1 | 4-helical cytokines |
| View | Download | 0.207 | 0.009 | vacuolar transport | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.206 | 0.009 | vacuolar transport | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.205 | 0.009 | vacuolar transport | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.205 | 0.009 | vacuolar transport | a.118.7 | 14-3-3 protein |
| View | Download | 0.204 | 0.009 | vacuolar transport | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.201 | 0.009 | vacuolar transport | a.87.1 | DBL homology domain (DH-domain) |
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Region A: Residues: [292-384] |
1 11 21 31 41 51
| | | | | |
1 LVEFIDFDGF KETLEKKQKE LIKDNDFIYH ESVPAVVQVD SIKALDAIKS PTWEKILEPY 60
61 MQDVANKCDS LYRGIIPLDV YEKESIYSEE KAT
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| Detection Method: | |
| Confidence: | 6.154902 |
| Match: | 1c1gA_ |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [385-752] |
1 11 21 31 41 51
| | | | | |
1 LLRKQVEETE TANLEYSSFI EFTNLPRLLS DLEKQFSDGN IFSNTDTQGQ LMRDQIQTWC 60
61 KFIQTNEFRD IEEQMNKIVF KRKQILEILS ALPNDQKENV TKLKSSLVAA SNSDEKLFAC 120
121 VKPHIVEINL LNDNGKIWKK FDEFNRNTPP QPSLLDIDDT KNDKILELLK QVKGHAEDLR 180
181 TLKEERSRNL SELRDEINND DITKLLIINK GKSDVELKDL FEVELEKFEP LSTRIEATIY 240
241 KQSSMIDDIK AKLDEIFHLS NFKDKSSGEE KFLEDRKNFF DKLQEAVKSF SIFASDLPKG 300
301 IEFYDSLFNM SRDLAERVRV AKQTEDSTAN SPAPPLPPLD SKASVVGGPP LLPQKSAAFQ 360
361 SLSRQGLN
|
| Detection Method: | |
| Confidence: | 14.30103 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [753-844] |
1 11 21 31 41 51
| | | | | |
1 LGDQFQNLKI SAGSDLPQGP GIPPRTYEAS PYAATPTMAA PPVPPKQSQE DMYDLRRRKA 60
61 VENEERELQE NPTSFYNRPS VFDENMYSKY SS
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.214 | a.24.17 | Group V grass pollen allergen |
