YRC Public Data Repository - Protein Structure Prediction

Protein:	GRX5
Organism:	Saccharomyces cerevisiae
Length:	150 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRX5.

Description	E-value	Query Range	Subject Range
GRX5 - Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial ... GLRX5_YEAST - Monothiol glutaredoxin-5, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...	6.0E-39	[1..150]	[1..150]
gi\|85099869 - gi\|85099869\|ref\|XP_960860.1\| monothiol glutaredoxin-5, mitochondrial precursor [Neurospora crassa OR... gi\|32405650, gi\|... - gi\|32405650\|ref\|XP_323438.1\| hypothetical protein [Neurospora crassa], gi\|28950367\|emb\|CAD71022.1\| p...	5.0E-33	[11..150]	[15..160]
gi\|162354157, gi... - gi\|77633720\|ref\|ZP_00795839.1\| COG0278: Glutaredoxin-related protein [Yersinia pestis Angola], gi\|16... gi\|152959757, gi... - gi\|77629368\|ref\|ZP_00791954.1\| COG0278: Glutaredoxin-related protein [Yersinia pseudotuberculosis IP... gi\|167422119, gi... - gi\|167422119\|ref\|ZP_02313872.1\| monothiol glutaredoxin GrxD [Yersinia pestis biovar Orientalis str. ... gi\|167056072, gi... - gi\|167424885\|ref\|ZP_02316638.1\| monothiol glutaredoxin GrxD [Yersinia pestis biovar Mediaevalis str.... gi\|167469391 - gi\|167469391\|ref\|ZP_02334095.1\| monothiol glutaredoxin GrxD [Yersinia pestis FV-1] gi\|170024105, gi... - gi\|170024105\|ref\|YP_001720610.1\| hypothetical protein YPK_1866 [Yersinia pseudotuberculosis YPIII], ... gi\|186698702, gi... - gi\|186895676\|ref\|YP_001872788.1\| hypothetical protein YPTS_2370 [Yersinia pseudotuberculosis PB1/+],... gi\|51589903, gi\|... - gi\|51596621\|ref\|YP_070812.1\| hypothetical protein YPTB2297 [Yersinia pseudotuberculosis IP 32953], g... Q66A35\|Q66A35_YERPS - Putative uncharacterized protein - Yersinia pseudotuberculosis gi\|25318358 - pir\|\|AH0290 conserved hypothetical protein YPO2383 [imported] - Yersinia pestis (strain CO92) gi\|229898471, gi... - gi\|229898471\|ref\|ZP_04513617.1\| monothiol glutaredoxin [Yersinia pestis biovar Orientalis str. India... gi\|16122606, gi\|... - gi\|218929474\|ref\|YP_002347349.1\| hypothetical protein YPO2383 [Yersinia pestis CO92], gi\|16122606\|re... gi\|229701957, gi... - gi\|229895069\|ref\|ZP_04510246.1\| monothiol glutaredoxin [Yersinia pestis Pestoides A], gi\|229701957\|g... gi\|165913513, gi... - gi\|89103796\|ref\|ZP_01176360.1\| COG0278: Glutaredoxin-related protein [Yersinia pestis biovar Orienta... gi\|165926467, gi... - gi\|165926467\|ref\|ZP_02222299.1\| monothiol glutaredoxin GrxD [Yersinia pestis biovar Orientalis str. ... gi\|229837908, gi... - gi\|229837908\|ref\|ZP_04458067.1\| monothiol glutaredoxin [Yersinia pestis biovar Orientalis str. PEXU2... gi\|108779637, gi... - gi\|108807724\|ref\|YP_651640.1\| hypothetical protein YPA_1729 [Yersinia pestis Antiqua], gi\|108779637\|... gi\|166010638, gi... - gi\|166010638\|ref\|ZP_02231536.1\| monothiol glutaredoxin GrxD [Yersinia pestis biovar Antiqua str. E19... gi\|229902311, gi... - gi\|229902311\|ref\|ZP_04517431.1\| monothiol glutaredoxin [Yersinia pestis Nepal516], gi\|229680646\|gb\|E... gi\|166210851, gi... - gi\|166210851\|ref\|ZP_02236886.1\| monothiol glutaredoxin GrxD [Yersinia pestis biovar Antiqua str. B42... gi\|167400819, gi... - gi\|167400819\|ref\|ZP_02306325.1\| monothiol glutaredoxin GrxD [Yersinia pestis biovar Antiqua str. UG0... gi\|145209762, gi... - gi\|145598066\|ref\|YP_001162142.1\| hypothetical protein YPDSF_0763 [Yersinia pestis Pestoides F], gi\|1... gi\|149292119, gi... - gi\|149365706\|ref\|ZP_01887741.1\| hypothetical protein YPE_0880 [Yersinia pestis CA88-4125], gi\|149292...	7.0E-33	[32..145]	[1..111]
gi\|62127655, gi\|... - gi\|62180022\|ref\|YP_216439.1\| hypothetical protein SC1452 [Salmonella enterica subsp. enterica serova... gi\|168229806, gi... - gi\|205335337\|gb\|EDZ22101.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... lcl\|NC_016856.1_... - [gene=ydhD] [protein=hypothetical protein] [protein_id=YP_005237303.1] [location=1521253..1521600] gi\|205327842, gi... - gi\|205327842\|gb\|EDZ14606.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... gi\|167551597, gi... - gi\|205323629\|gb\|EDZ11468.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... gi\|161363512, gi... - gi\|161614148\|ref\|YP_001588113.1\| hypothetical protein SPAB_01888 [Salmonella enterica subsp. enteric... gi\|56127855, gi\|... - gi\|56413598\|ref\|YP_150673.1\| hypothetical protein SPA1420 [Salmonella enterica subsp. enterica serov... gi\|197093999, gi... - gi\|197362522\|ref\|YP_002142159.1\| hypothetical protein SSPA1320 [Salmonella enterica subsp. enterica ... gi\|197241747, gi... - gi\|197263492\|ref\|ZP_03163566.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica... gi\|16760480 - gi\|16760480\|ref\|NP_456097.1\| hypothetical protein STY1689 [Salmonella enterica subsp. enterica serov... gi\|197249772, gi... - gi\|197249772\|ref\|YP_002146612.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enteric... gi\|194737105, gi... - gi\|194737105\|ref\|YP_002114444.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enteric... gi\|207857063, gi... - gi\|207857063\|ref\|YP_002243714.1\| hypothetical protein SEN1614 [Salmonella enterica subsp. enterica s... gi\|205352853, gi... - gi\|205352853\|ref\|YP_002226654.1\| hypothetical protein SG1685 [Salmonella enterica subsp. enterica se... gi\|238913166 - gi\|238913166\|ref\|ZP_04657003.1\| hypothetical protein SentesTe_18835 [Salmonella enterica subsp. ente... gi\|199602405, gi... - gi\|200389960\|ref\|ZP_03216571.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica... gi\|197940257, gi... - gi\|198245741\|ref\|YP_002215701.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enteric... gi\|168463156, gi... - gi\|195633901\|gb\|EDX52253.1\| glutaredoxin-4 [Salmonella enterica subsp. enterica serovar Newport str.... gi\|205346858, gi... - gi\|205346858\|gb\|EDZ33489.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... gi\|168240947, gi... - gi\|205339531\|gb\|EDZ26295.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... gi\|168235504, gi... - gi\|197290954\|gb\|EDY30307.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... gi\|194470567, gi... - gi\|194470567\|ref\|ZP_03076551.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica... gi\|194448379, gi... - gi\|194448379\|ref\|YP_002045471.1\| hypothetical protein SeHA_C1603 [Salmonella enterica subsp. enteric... gi\|194445820, gi... - gi\|194445820\|ref\|YP_002040682.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enteric... gi\|205343668, gi... - gi\|205343668\|gb\|EDZ30432.1\| putative monothiol glutaredoxin [Salmonella enterica subsp. enterica ser... gi\|213612349 - gi\|213612349\|ref\|ZP_03370175.1\| hypothetical protein SentesTyp_07509 [Salmonella enterica subsp. ent... gi\|213586460 - gi\|213586460\|ref\|ZP_03368286.1\| hypothetical protein SentesTyph_36386 [Salmonella enterica subsp. en... gi\|213426004 - gi\|213426004\|ref\|ZP_03358754.1\| hypothetical protein SentesTyphi_10349 [Salmonella enterica subsp. e... gi\|213161998 - gi\|213161998\|ref\|ZP_03347708.1\| hypothetical protein Salmoneentericaenterica_19157 [Salmonella enter... gi\|16764781, gi\|... - gi\|16764781\|ref\|NP_460396.1\| hypothetical protein STM1433 [Salmonella typhimurium LT2], gi\|16419953\|... gi\|224468585, gi... - gi\|224584058\|ref\|YP_002637856.1\| hypothetical protein SPC_2298 [Salmonella enterica subsp. enterica ... gi\|29137388, gi\|... - gi\|29141760\|ref\|NP_805102.1\| hypothetical protein t1301 [Salmonella enterica subsp. enterica serovar... gi\|214000296 - gi\|214000296\|ref\|ZP_03411031.1\| hypothetical protein Salmonellentericaenterica_06486 [Salmonella ent... gi\|213855188 - gi\|213855188\|ref\|ZP_03383428.1\| hypothetical protein SentesT_14372 [Salmonella enterica subsp. enter... gi\|16502776, gi\|... - gi\|25318360\|pir\|\|AE0695 conserved hypothetical protein STY1689 [imported] - Salmonella enterica subs... gi\|213649692 - gi\|213649692\|ref\|ZP_03379745.1\| hypothetical protein SentesTy_21810 [Salmonella enterica subsp. ente...	7.0E-33	[32..148]	[2..115]
YDHD_ECOLI - Probable monothiol glutaredoxin ydhD - Escherichia coli gi\|75234965, gi\|... - gi\|75234965\|ref\|ZP_00719244.1\| COG0278: Glutaredoxin-related protein [Escherichia coli E110019], gi\|... gi\|91210868, gi\|... - gi\|91210868\|ref\|YP_540854.1\| hypothetical protein UTI89_C1845 [Escherichia coli UTI89], gi\|91072442\|... gi\|191173466, gi... - gi\|75238787\|ref\|ZP_00722771.1\| COG0278: Glutaredoxin-related protein [Escherichia coli F11], gi\|1911... gi\|13361830, gi\|... - gi\|15831617\|ref\|NP_310390.1\| hypothetical protein ECs2363 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|193064910, gi... - gi\|75257073\|ref\|ZP_00728633.1\| COG0278: Glutaredoxin-related protein [Escherichia coli E22], gi\|1930... gi\|110641775, gi... - gi\|110641775\|ref\|YP_669505.1\| hypothetical protein ECP_1599 [Escherichia coli 536], gi\|110343367\|gb\|... gi\|188495397, gi... - gi\|75512912\|ref\|ZP_00735393.1\| COG0278: Glutaredoxin-related protein [Escherichia coli 53638], gi\|18... gi\|110805632, gi... - gi\|110805632\|ref\|YP_689152.1\| hypothetical protein SFV_1676 [Shigella flexneri 5 str. 8401], gi\|1106... gi\|81241278, gi\|... - gi\|82777130\|ref\|YP_403479.1\| hypothetical protein SDY_1880 [Shigella dysenteriae Sd197], gi\|81241278... gi\|81245389, gi\|... - gi\|82543978\|ref\|YP_407925.1\| hypothetical protein SBO_1479 [Shigella boydii Sb227], gi\|81245389\|gb\|A... gi\|1742727, gi\|8... - gi\|89108496\|ref\|AP_002276.1\| hypothetical protein [Escherichia coli str. K-12 substr. W3110], gi\|174... gi\|83587988, gi\|... - gi\|83587988\|ref\|ZP_00926614.1\| COG0278: Glutaredoxin-related protein [Escherichia coli 101-1], gi\|19... gi\|187429934, gi... - gi\|75178444\|ref\|ZP_00698490.1\| COG0278: Glutaredoxin-related protein [Shigella boydii BS512], gi\|187... gi\|157155524, gi... - gi\|75190693\|ref\|ZP_00703960.1\| COG0278: Glutaredoxin-related protein [Escherichia coli E24377A], gi\|... gi\|157161118, gi... - gi\|75195733\|ref\|ZP_00705803.1\| COG0278: Glutaredoxin-related protein [Escherichia coli HS], gi\|15716... gi\|194416117, gi... - gi\|75212990\|ref\|ZP_00712988.1\| COG0278: Glutaredoxin-related protein [Escherichia coli B171], gi\|194... gi\|190904013, gi... - gi\|75230898\|ref\|ZP_00717347.1\| COG0278: Glutaredoxin-related protein [Escherichia coli B7A], gi\|1911... gi\|117623837, gi... - gi\|117623837\|ref\|YP_852750.1\| hypothetical protein APECO1_735 [Escherichia coli APEC O1], gi\|1155129... gi\|124531615, gi... - gi\|124531615\|ref\|ZP_01701826.1\| glutaredoxin-like protein [Escherichia coli B], gi\|124498470\|gb\|EAY4... gi\|208731024, gi... - gi\|208816681\|ref\|ZP_03257801.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC404... gi\|208724927, gi... - gi\|208810411\|ref\|ZP_03252287.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC420... gi\|227885928, gi... - gi\|227885928\|ref\|ZP_04003733.1\| glutaredoxin [Escherichia coli 83972], gi\|227837107\|gb\|EEJ47573.1\| g... YDHD_ECOL6, GLRX... - Probable monothiol glutaredoxin ydhD - Escherichia coli O6, Glutaredoxin-4 OS=Escherichia coli O6 GN... gi\|209398586, gi... - gi\|209398586\|ref\|YP_002270723.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC41... gi\|237705600, gi... - gi\|237705600\|ref\|ZP_04536081.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|208818969, gi... - gi\|208818969\|ref\|ZP_03259289.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC404... gi\|238900870, gi... - gi\|238900870\|ref\|YP_002926666.1\| hypothetical protein BWG_1469 [Escherichia coli BW2952], gi\|2388603... gi\|215264902, gi... - gi\|215486830\|ref\|YP_002329261.1\| hypothetical protein E2348C_1740 [Escherichia coli O127:H6 str. E23... gi\|242377384, gi... - gi\|251785111\|ref\|YP_002999415.1\| hypothetical protein B21_01614 [Escherichia coli BL21], gi\|24237738... gi\|209918968, gi... - gi\|209918968\|ref\|YP_002293052.1\| hypothetical protein ECSE_1777 [Escherichia coli SE11], gi\|20991222... gi\|253324431, gi... - gi\|254288505\|ref\|YP_003054253.1\| hypothetical protein ECD_01624 [Escherichia coli BL21(DE3)], gi\|253... gi\|218360990, gi... - gi\|218554222\|ref\|YP_002387135.1\| hypothetical protein ECIAI1_1706 [Escherichia coli IAI1], gi\|218360... gi\|254161716, gi... - gi\|254161716\|ref\|YP_003044824.1\| hypothetical protein ECB_01624 [Escherichia coli B str. REL606], gi... gi\|217318247, gi... - gi\|217328900\|ref\|ZP_03444981.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. TW145... gi\|254592671, gi... - gi\|254793271\|ref\|YP_003078108.1\| monothiol glutaredoxin [Escherichia coli O157:H7 str. TW14359], gi\|... gi\|168790559, gi... - gi\|189370004\|gb\|EDU88420.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC869], g... gi\|168783926, gi... - gi\|188998812\|gb\|EDU67798.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4076], ... gi\|170019994, gi... - gi\|170019994\|ref\|YP_001724948.1\| hypothetical protein EcolC_1975 [Escherichia coli ATCC 8739], gi\|16... gi\|168802773, gi... - gi\|189375328\|gb\|EDU93744.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC508], g... gi\|170680379, gi... - gi\|170680379\|ref\|YP_001743599.1\| putative monothiol glutaredoxin [Escherichia coli SMS-3-5], gi\|1705... gi\|170081317, gi... - gi\|170081317\|ref\|YP_001730637.1\| monothiol glutaredoxin [Escherichia coli str. K-12 substr. DH10B], ... gi\|195940217 - gi\|195940217\|ref\|ZP_03085599.1\| hypothetical protein EscherichcoliO157_28126 [Escherichia coli O157:... gi\|194417036, gi... - gi\|194434698\|ref\|ZP_03066951.1\| putative monothiol glutaredoxin [Shigella dysenteriae 1012], gi\|1944... GLRX4_SHIFL - Glutaredoxin-4 OS=Shigella flexneri GN=grxD PE=3 SV=1 GLRX4_ECOL6 - Glutaredoxin-4 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=grxD PE=3 SV=1 gi\|24052014, gi\|... - gi\|24113044\|ref\|NP_707554.1\| hypothetical protein SF1682 [Shigella flexneri 2a str. 301], gi\|2405201... GLRX4_ECO57 - Glutaredoxin-4 OS=Escherichia coli O157:H7 GN=grxD PE=3 SV=1 gi\|30041422, gi\|... - gi\|30063170\|ref\|NP_837341.1\| hypothetical protein S1814 [Shigella flexneri 2a str. 2457T], gi\|300414... gi\|12515649, gi\|... - gi\|15802068\|ref\|NP_288090.1\| hypothetical protein Z2676 [Escherichia coli O157:H7 EDL933], gi\|125156... EG12181 - glutaredoxin-4 / Monothiol glutaredoxin Grx4 with CGFS motif; substrate for thioredoxin reductase; m... gi\|218427163, gi... - gi\|218689599\|ref\|YP_002397811.1\| hypothetical protein ECED1_1853 [Escherichia coli ED1a], gi\|2184271... gi\|218558525, gi... - gi\|218558525\|ref\|YP_002391438.1\| hypothetical protein ECS88_1703 [Escherichia coli S88], gi\|21836529... gi\|218699778, gi... - gi\|218699778\|ref\|YP_002407407.1\| hypothetical protein ECIAI39_1402 [Escherichia coli IAI39], gi\|2183... gi\|218351949, gi... - gi\|218695217\|ref\|YP_002402884.1\| hypothetical protein EC55989_1822 [Escherichia coli 55989], gi\|2183... gi\|218705154, gi... - gi\|218705154\|ref\|YP_002412673.1\| hypothetical protein ECUMN_1944 [Escherichia coli UMN026], gi\|21843... gi\|168752331, gi... - gi\|188013798\|gb\|EDU51920.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4113], ... gi\|189364910, gi... - gi\|189364910\|gb\|EDU83326.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4501], ... EG12181 - glutaredoxin-4 / Monothiol glutaredoxin Grx4 with CGFS motif; substrate for thioredoxin reductase; m... gi\|168758990, gi... - gi\|189354317\|gb\|EDU72736.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4401], ... gi\|168775887, gi... - gi\|187768670\|gb\|EDU32514.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4196], ... gi\|189360007, gi... - gi\|189360007\|gb\|EDU78426.1\| putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4486], ...	7.0E-33	[32..148]	[2..115]
gi\|22294596, gi\|... - gi\|22298417\|ref\|NP_681664.1\| hypothetical protein tll0874 [Thermosynechococcus elongatus BP-1], gi\|2...	1.0E-32	[21..138]	[6..120]
gi\|22125845, gi\|... - gi\|22125845\|ref\|NP_669268.1\| hypothetical protein y1953 [Yersinia pestis KIM], gi\|21958776\|gb\|AAM855... gi\|45436824, gi\|... - gi\|45441961\|ref\|NP_993500.1\| hypothetical protein YP_2169 [Yersinia pestis biovar Microtus str. 9100...	2.0E-32	[32..145]	[6..116]
gi\|28193244 - gi\|28193244\|emb\|CAD62364.1\| unnamed protein product [Homo sapiens]	2.0E-32	[36..150]	[62..173]
GLRX4_PASMU - Glutaredoxin-4 OS=Pasteurella multocida (strain Pm70) GN=grxD PE=3 SV=1 GLRX4_PASMU - Glutaredoxin-4 OS=Pasteurella multocida GN=grxD PE=3 SV=1	2.0E-32	[32..143]	[1..109]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLPKFNPIR SFSPILRAKT LLRYQNRMYL STEIRKAIED AIESAPVVLF MKGTPEFPKC  60
   61 GFSRATIGLL GNQGVDPAKF AAYNVLEDPE LREGIKEFSE WPTIPQLYVN KEFIGGCDVI 120
  121 TSMARSGELA DLLEEAQALV PEEEEETKDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.0
Match:	1kte__
Description:	Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits