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View Structure Prediction Details

Protein: YPL009C
Organism: Saccharomyces cerevisiae
Length: 1038 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPL009C.

Description E-value Query
Range
Subject
Range
NEMF_MOUSE - Nuclear export mediator factor Nemf OS=Mus musculus GN=Nemf PE=1 SV=2
640.0 [0..1] [1027..1]
HGNC:10663|MIM:6... - defined colon cancer antigen 1
SDCCAG1 - serologically defined colon cancer antigen 1
gi|151556560, gi... - gi|151556560|gb|AAI48733.1| Serologically defined colon cancer antigen 1 [synthetic construct], gi|1...
637.0 [0..1] [1027..1]
gi|55640675 - gi|55640675|ref|XP_509934.1| PREDICTED: serologically defined colon cancer antigen 1 [Pan troglodyte...
636.0 [0..1] [1027..1]
gi|73962860 - gi|73962860|ref|XP_851229.1| PREDICTED: similar to serologically defined colon cancer antigen 1 isof...
623.0 [0..1] [1027..1]
gi|76667208 - gi|76667208|ref|XP_869312.1| PREDICTED: similar to serologically defined colon cancer antigen 1 isof...
610.0 [0..1] [1027..1]
RQC2_SCHPO - Ribosome quality control complex subunit 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN...
SPCC132.01c - DUF814 family protein
594.0 [0..1] [1028..1]
gi|8777424, gi|1... - gi|8777424|dbj|BAA97014.1| unnamed protein product [Arabidopsis thaliana], gi|15240582|ref|NP_199804...
553.0 [0..2] [1021..3]

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Predicted Domain #1
Region A:
Residues: [1-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQRISALDL LLLARELKQD LEGYRLSNIY NIADSSKQFL LKFNKPDSKL NVVVDCGLRI  60
   61 YLTEFSRPIP PTPSGFVVKL RKHLKAKRLT ALKQVDQDRI LVLQFADGHF YLVLEFFSAG 120
  121 NVILLDENRR IMALQRVVLE HENKVGQIYE MFDESLFTTN NESADESIEK NRKAEYTSEL 180
  181 VNEWIKAVQA KYESDITVIK QLNIQGKEGA KKKKVKVPSI HKLLLSKVPH LSSDLLSKNL 240
  241 KVFNIDPSES CLNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [255-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEETDSLAEL LNSTQLEYNQ LLTTTDRKGY ILAKRNENYI SEKDTADLEF IYDTFHPFKP  60
   61 YINGGDTDSS CIIEVEGPYN RTLDKFFSTI ESSKYALRIQ NQESQAQKKI DDARAENDRK 120
  121 IQALLDVQEL NERKGHLIIE NAPLIEEVKL AVQGLIDQQM DWNTIEKLIK SEQKKGNRIA 180
  181 QLLNLPLNLK QNKISVKLDL SSKELNTSSD EDNESEGNTT DSSSDSDSED MESSKERSTK 240
  241 SMKRKSNEKI NVTIDLGLSA YANATEYFNI KKTSAQKQKK VEKNVGKAMK NIEVKIDQQL 300
  301 KKKLKDSHSV LKKIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [570-700]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPYFFEKYSW FISSEGFLVM MGKSPAETDQ IYSKYIEDDD IYMSNSFNSH VWIKNPEKTE  60
   61 VPPNTLMQAG ILCMSSSEAW SKKISSSPWW CFAKNVSKFD GSDNSILPEG AFRLKNENDQ 120
  121 NHLPPAQLVM G

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.612 N/A N/A d.21.1 Diaminopimelate epimerase-like
View Download 0.564 N/A N/A d.371.1 Description not found.
View Download 0.550 N/A N/A d.21.1 Diaminopimelate epimerase-like
View Download 0.539 N/A N/A d.110.7 Description not found.
View Download 0.510 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.510 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.508 N/A N/A d.21.1 Diaminopimelate epimerase-like
View Download 0.480 N/A N/A d.93.1 SH2 domain
View Download 0.445 N/A N/A a.60.9 lambda integrase-like, N-terminal domain

Predicted Domain #4
Region A:
Residues: [701-928]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGFLWKVKTS GNEDNGDDDE EEEEEEEEEE EEEEEEEEEE EEEKEEEEKE EEQQQDEDDS  60
   61 NEVNGLEKGG DSNDSTKNNS FEHDNLEKDI EKHCTISSDT DSDSGNAKAK NDNSSTQRIL 120
  121 DEPGVPISLI ENINSNVRGK RGKLKKIQKK YADQDETERL LRLEALGTLK GIEKQQQRKK 180
  181 EEIMKREVRE DRKNKREKQR RLQALKFTKK EKARVNYDKH KSELKPSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [929-1038]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKGDVVDDII PVFAPWPALL KYKYKVKIQP GSAKKTKTLT EILHYFKSRP LDGSSTDNEM  60
   61 DWPQEHEMIK GLKEQDLVLL LCVDKLKVTI AGQKSTKNGG NSSKKGKKKR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.770 d.370.1 Description not found.
View Download 0.533 a.24.4 Hemerythrin
View Download 0.532 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.479 a.4.5 "Winged helix" DNA-binding domain
View Download 0.479 a.4.5 "Winged helix" DNA-binding domain
View Download 0.458 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.394 a.138.1 Multiheme cytochromes
View Download 0.373 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle