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View Structure Prediction Details

Protein: FDH1
Organism: Saccharomyces cerevisiae
Length: 376 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FDH1.

Description E-value Query
Range
Subject
Range
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...
0.0 [20..372] [1..327]
GYAR_THELI - Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1
GYAR_THELN - Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=g...
0.0 [19..371] [1..331]
gi|14601656, gi|... - gi|5105521|dbj|BAA80834.1| 347aa long hypothetical D-3-phosphoglycerate dehydrogenase [Aeropyrum per...
gi|7431353 - pir||E72568 probable D-3-phosphoglycerate dehydrogenase APE1831 - Aeropyrum pernix (strain K1)
0.0 [17..368] [12..345]
gi|22294046, gi|... - gi|22297868|ref|NP_681115.1| D-3-phosphoglycerate dehydrogenase [Thermosynechococcus elongatus BP-1]...
0.0 [20..372] [1..328]
GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus GN=gyaR PE=3 SV=1
GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=gyaR ...
0.0 [19..359] [1..322]
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 /...
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus GN=serA PE=3 SV=1
0.0 [21..364] [1..317]
gi|254717444 - gi|254717444|ref|ZP_05179255.1| D-3-phosphoglycerate dehydrogenase [Brucella ceti M13/05/1]
gi|254719689 - gi|254719689|ref|ZP_05181500.1| D-3-phosphoglycerate dehydrogenase [Brucella sp. 83/13]
gi|161336427, gi... - gi|161619616|ref|YP_001593503.1| D-3-phosphoglycerate dehydrogenase [Brucella canis ATCC 23365], gi|...
gi|148559678, gi... - gi|148559678|ref|YP_001259539.1| D-3-phosphoglycerate dehydrogenase [Brucella ovis ATCC 25840], gi|1...
gi|23502543, gi|... - gi|23502543|ref|NP_698670.1| D-3-phosphoglycerate dehydrogenase [Brucella suis 1330], gi|23348542|gb...
gi|254708447 - gi|254708447|ref|ZP_05170275.1| D-3-phosphoglycerate dehydrogenase [Brucella pinnipedialis M163/99/1...
gi|254714547 - gi|254714547|ref|ZP_05176358.1| D-3-phosphoglycerate dehydrogenase [Brucella ceti M644/93/1]
gi|254703466 - gi|254703466|ref|ZP_05165294.1| D-3-phosphoglycerate dehydrogenase [Brucella suis bv. 3 str. 686]
0.0 [19..370] [1..326]
gi|25283945 - pir||AG3295 phosphoglycerate dehydrogenase (EC 1.1.1.95) [imported] - Brucella melitensis (strain 16...
gi|17986632, gi|... - gi|17986632|ref|NP_539266.1| D-3-phosphoglycerate dehydrogenase [Brucella melitensis 16M], gi|179822...
0.0 [17..370] [4..331]
gi|25283944, gi|... - pir||AF3012 D-3-phosphoglycerate dehydrogenase serA [imported] - Agrobacterium tumefaciens (strain C...
gi|17937411, gi|... - gi|17937411|ref|NP_534200.1| D-3-phosphoglycerate dehydrogenase [Agrobacterium tumefaciens str. C58]...
0.0 [19..370] [1..326]
gi|7431368 - gi|7431368|pir||H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain...
SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...
0.0 [20..372] [3..328]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKGKVLLVL YEGGKHAEEQ EKLLGCIENE LGIRNFIEEQ GYELVTTIDK DPEPTSTVDR  60
   61 ELKDAEIVIT TPFFPAYISR NRIAEAPNLK LCVTAGVGSD HVDLEAANER KITVTEVTGS 120
  121 NVV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [327-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTSLDAQKR YAQGVKNILN SYFSKKFDYR PQDIIVQNGS YATRAYGQKK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 953.218487
Match: 2nacA_
Description: Formate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [124-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVAEHVMATI LVLIRNYNGG HQQAINGEWD IAGVAKNEYD LEDKIISTVG AGRIGYRVLE  60
   61 RLVAFNPKKL LYYDYQELPA EAINRLNEAS KLFNGRGDIV QRVEKLEDMV AQSDVVTINC 120
  121 PLHKDSRGLF NKKLISHMKD GAYLVNTARG AICVAEDVAE AVKSGKLAGY GGDVWDKQPA 180
  181 PKDHPWRTMD NKDHVGNAMT VHI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 953.218487
Match: 2nacA_
Description: Formate dehydrogenase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle