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View Structure Prediction Details

Protein: GPB1
Organism: Saccharomyces cerevisiae
Length: 897 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPB1.

Description E-value Query
Range
Subject
Range
GPB1 - Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby incre...
GPB1_YEAST - Guanine nucleotide-binding protein subunit beta 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
0.0 [1..897] [1..897]
gi|71072673, gi|... - gi|71072673|ref|XP_768891.1| hypothetical protein GLP_47_40415_39147 [Giardia lamblia ATCC 50803], g...
ctg02_16|6072|Hy... - protein
GL50803_6072 - | organism=Giardia_Assemblage_A_isolate_WB | product=hypothetical protein | location=GLCHR02:705408-...
0.001 [659..756] [282..384]

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Predicted Domain #1
Region A:
Residues: [1-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQASTFGSH SLEAHPLHIQ PAVHIKLSKE ERSHYREQYD SLKYISNYVS VFDQALSDNI  60
   61 DSRIRKENEA LLKKYYESRK PFTFTSFRQG SVISSSDSST GFTERTKTYC FLNDFVSNCV 120
  121 NEVDPYTLKM TVRNRNTALN MENLDDERKS KDDIYDFEDN TDDECNAKCH GAFHYSSERL 180
  181 EILRSRSTIS YFKYYKKLLT VDLRDSDVLK RHNLWMPMIT RRFRFLLVSS SKPEDVRLTT 240
  241 PIPTFSESDL DIFKNKTCPL FINGTDCVPR SYDTFSGSSV IASIFSEYKL PSLSYHCSVE 300
  301 LNDQLFIVGG LMACHRYDEE APDLKDFYVD GIKNLPPPLI PELINNPSMI PNPHLYCFSL 360
  361 TSSRLTRPDI SGYIPPPLVC TQGCKLTERH IFLYGGFEIK SETQVDDKGR YFIRKRAFLN 420
  421 NTGYILDTVT FNFSKIELVA PPYQFAIYNN FSPRFGHMQA SISNSNNNVS NENTTTSAKG 480
  481 RRSISPYRQG NGDHKIDDLV GSPGSTDYLE DDAIPPVTNP RSTDSLSSKH CSTATHICSS 540
  541 VNTILIFGGY SQTGDDKYEA MNDMWKINIP VVSRGKRNYY KFADTVTATK IPIIDDPELW 600
  601 PSRRAFSACC VPDYFTKDVE PIETRLLRNL KNDFSIDLEI RPGNK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [646-794]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSQPLFPNIP HSRKEKKSGR DSMHISNSNN STSEDTSSKS TRNTTSSPPT SPKHTPPLNP  60
   61 SKKCASIGRT IAFHGGSDGY DVCSDMWWFD FDSETWTKID LYAKTQEESD GLVPINLCMV 120
  121 GHSMTTVGHK VVLIGGLRQG DVDRIYRDE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [795-897]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLPEEVISGV PLGSGVINVV DLNTQCLQGC KLIRNDGDTK ESVIMDPHVG TPHQVLAVAG  60
   61 TIELVKGTMT LIGGVVAGRE DISSLYLRGA VLQFILPSMN LAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle