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View Structure Prediction Details

Protein: DGK1
Organism: Saccharomyces cerevisiae
Length: 290 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DGK1.

Description E-value Query
Range
Subject
Range
gi|207340900 - gi|207340900|gb|EDZ69108.1| YOR311Cp-like protein [Saccharomyces cerevisiae AWRI1631]
DGK1 - Diacylglycerol kinase, localized to the endoplasmic reticulum (ER); overproduction induces enlargeme...
DGK1_YEAST - CTP-dependent diacylglycerol kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DG...
gi|190407611 - gi|190407611|gb|EDV10878.1| ER membrane protein [Saccharomyces cerevisiae RM11-1a]
2.0E-69 [1..290] [1..290]
gi|8843778 - gi|8843778|dbj|BAA97326.1| unnamed protein product [Arabidopsis thaliana]
9.0E-48 [20..236] [49..268]
gi|85082020 - gi|85082020|ref|XP_956828.1| hypothetical protein [Neurospora crassa OR74A]
gi|28917907, gi|... - gi|32404052|ref|XP_322639.1| hypothetical protein [Neurospora crassa], gi|28917907|gb|EAA27592.1| hy...
8.0E-43 [62..288] [350..596]
DGK1_SCHPO - CTP-dependent diacylglycerol kinase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ptp4...
ptp4 - phosphatidate cytidylyltransferase Ptp4
1.0E-42 [62..285] [4..218]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTEDAIALP NSTLEPRTEA KQRLSSKSHQ VSAKVTIPAK EEISSSDDDA HVPVTEIHLK  60
   61 SHEWFGDFIT KHEIP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.604 d.58.7 RNA-binding domain, RBD
View Download 0.545 d.58.5 GlnB-like
View Download 0.773 d.58.8 Viral DNA-binding domain
View Download 0.639 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.541 d.74.2 C-terminal domain of arginine repressor
View Download 0.520 d.94.1 HPr-like
View Download 0.494 d.40.1 CI-2 family of serine protease inhibitors
View Download 0.481 c.47.1 Thioredoxin-like
View Download 0.462 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.450 d.58.14 Ribosomal protein S6
View Download 0.440 c.47.1 Thioredoxin-like
View Download 0.434 d.58.17 Metal-binding domain
View Download 0.430 d.58.7 RNA-binding domain, RBD
View Download 0.412 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.398 d.94.1 HPr-like
View Download 0.378 c.47.1 Thioredoxin-like
View Download 0.376 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.370 d.57.1 DNA damage-inducible protein DinI
View Download 0.350 d.58.3 Protease propeptides/inhibitors
View Download 0.333 d.58.10 Acylphosphatase-like
View Download 0.323 d.52.1 Alpha-lytic protease prodomain
View Download 0.316 d.41.2 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
View Download 0.311 a.77.1 DEATH domain
View Download 0.305 d.129.1 TATA-box binding protein-like
View Download 0.271 d.201.1 SRP19
View Download 0.267 b.1.1 Immunoglobulin
View Download 0.265 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.262 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.253 d.58.35 Pseudouridine synthase
View Download 0.242 d.28.1 Ribosomal protein S19
View Download 0.242 d.230.2 Flavin-binding protein dodecin
View Download 0.242 d.58.12 eEF-1beta-like
View Download 0.234 d.58.13 Anticodon-binding domain of PheRS
View Download 0.214 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain

Predicted Domain #2
Region A:
Residues: [76-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKVFHSSIGF ITLYLYTQGI NYKNVLWPLI YAFIILFILD LIRLNWPFFN MLYCRTVGAL  60
   61 MRKKEIHTYN GVLWYILGLI FSFNFFSKDV TLISLFLLSW SDTAAATIGR KYGHLTPKVA 120
  121 RNKSLAGSIA AFTVGVITCW VFYGYFVPAY SYVNKPGEIQ WSPETSRLSL NMLSLLGGVV 180
  181 AALSEGIDLF NWDDNFTIPV LSSLFMNAVI KTFKK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 84.568636
Match: PF01879
Description: No description for PF01879 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle