YRC Public Data Repository - Protein Structure Prediction

Protein:	MPD1
Organism:	Saccharomyces cerevisiae
Length:	318 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPD1.

Description	E-value	Query Range	Subject Range
MPD1 - Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone ac... MPD1_YEAST - Protein disulfide-isomerase MPD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPD1 PE...	2.0E-64	[1..318]	[1..318]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-53	[7..306]	[3..296]
gi\|303618 - gi\|303618\|dbj\|BAA03759.1\| phospholipase C-alpha [Homo sapiens]	1.0E-51	[7..306]	[3..296]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	2.0E-51	[7..306]	[3..296]
gi\|8393322, gi\|9... - gi\|927670\|dbj\|BAA09695.1\| ER-60 protease [Rattus norvegicus], gi\|8393322\|ref\|NP_059015.1\| protein di...	2.0E-51	[7..306]	[3..296]
gi\|16508150 - gi\|16508150\|gb\|AAL18160.1\| ERP57 protein [Cricetulus griseus]	5.0E-51	[7..306]	[3..296]
PDIA3_MOUSE - Protein disulfide-isomerase A3 OS=Mus musculus GN=Pdia3 PE=1 SV=2	7.0E-51	[7..306]	[3..296]

Back

Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFLNIIKLL LGLFIMNEVK AQNFYDSDPH ISELTPKSFD KAIHNTNYTS LVEFYAPWCG  60
   61 HCKKLSSTFR KAAKRLDGVV QVAAVNCDLN KNKALCAKYD VNGFPTLMVF RPPKIDLSKP 120
  121 IDNAKKSFSA HANEVYSGAR TLAPIVDFSL SRIRSY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	129.154902
Match:	1mek__
Description:	Protein disulfide isomerase, PDI
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [157-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKKFVRIDTL GSLLRKSPKL SVVLFSKQDK ISPVYKSIAL DWLGKFDFYS ISNKKLKQLT  60
   61 DMNPTYEKTP EIFKYLQKVI PEQRQSDKSK LVVFDADKDK FWEYEGNSIN KNDISKFLRD 120
  121 TFSITPNEGP FSRRSEYIAY LKTGKKPIKK NHSSSGNKHD EL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.154902
Match:	1bjx__
Description:	Protein disulfide isomerase, PDI
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits