YRC Public Data Repository - Protein Structure Prediction

Protein:	MGE1
Organism:	Saccharomyces cerevisiae
Length:	228 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MGE1.

Description	E-value	Query Range	Subject Range
GRPE_YEAST - GrpE protein homolog, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MGE1... gi\|151945320 - gi\|151945320\|gb\|EDN63563.1\| mitochondrial grpe [Saccharomyces cerevisiae YJM789] MGE1 - Mitochondrial matrix cochaperone, acts as a nucleotide release factor for Ssc1p in protein transloca... gi\|190407540 - gi\|190407540\|gb\|EDV10807.1\| hypothetical protein SCRG_01618 [Saccharomyces cerevisiae RM11-1a] gi\|207341003 - gi\|207341003\|gb\|EDZ69181.1\| YOR232Wp-like protein [Saccharomyces cerevisiae AWRI1631]	1.0E-54	[1..228]	[1..228]
GRPE1_MOUSE - GrpE protein homolog 1, mitochondrial OS=Mus musculus GN=Grpel1 PE=1 SV=1	1.0E-48	[1..224]	[1..215]
GRPE1_RAT - GrpE protein homolog 1, mitochondrial OS=Rattus norvegicus GN=Grpel1 PE=1 SV=2	1.0E-47	[1..224]	[1..215]
Roe1-PA - The gene Roe1 is referred to in FlyBase by the symbol Dmel\Roe1 (CG6155, FBgn0014877). It is a prote...	2.0E-45	[36..224]	[26..212]
gi\|26451456, gi\|... - gi\|29824143\|gb\|AAP04032.1\| putative grpE protein [Arabidopsis thaliana], gi\|26451456\|dbj\|BAC42827.1\|...	9.0E-45	[10..228]	[83..318]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-44	[1..226]	[6..238]
gi\|17983809, gi\|... - gi\|17988060\|ref\|NP_540694.1\| heat shock protein GrpE [Brucella melitensis 16M], gi\|17983809\|gb\|AAL52... gi\|25311554 - pir\|\|AC3474 grpE protein [imported] - Brucella melitensis (strain 16M)	2.0E-44	[67..225]	[1..159]
gi\|3851638 - gi\|3851638\|gb\|AAC72386.1\| chaperone GrpE type 1 [Nicotiana tabacum]	2.0E-43	[15..227]	[65..290]

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Predicted Domain #1

Region A:
Residues: [1-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAFSAATVR ATTRKSFIPM APRTPFVTPS FTKNVGSMRR MRFYSDEAKS EESKENNEDL  60
   61 TEEQSEIKKL ESQLSAKTKE ASELKDRLLR SVADFRNLQQ VTKKDIQKAK DFALQKFAKD 120
  121 LLESVDNFGH ALNAFKEEDL QKSKEISDLY TGVRMTRDVF ENTLRKHGIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	208.54902
Match:	1dkgA_
Description:	Head domain of nucleotide exchange factor GrpE; Coiled-coil domain of nucleotide exchange factor GrpE
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [171-228]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLDPLGEPFD PNKHEATFEL PQPDKEPGTV FHVQQLGFTL NDRVIRPAKV GIVKGEEN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	208.54902
Match:	1dkgA_
Description:	Head domain of nucleotide exchange factor GrpE; Coiled-coil domain of nucleotide exchange factor GrpE
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits