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View Structure Prediction Details

Protein: MCT1
Organism: Saccharomyces cerevisiae
Length: 384 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCT1.

Description E-value Query
Range
Subject
Range
gi|17131773, gi|... - gi|17230172|ref|NP_486720.1| polyketide synthase [Nostoc sp. PCC 7120], gi|17131773|dbj|BAB74379.1| ...
gi|25535295 - pir||AI2140 polyketide synthase [imported] - Nostoc sp. (strain PCC 7120)
6.0E-76 [51..369] [560..859]
gi|7478683 - pir||D70634 probable polyketide synthase cy338 - Mycobacterium tuberculosis (strain H37RV)
gi|3261706, gi|1... - gi|3261706|emb|CAB06605.1| PROBABLE MEMBRANE BOUND POLYKETIDE SYNTHASE PKS6 [Mycobacterium tuberculo...
gi|148660170, gi... - gi|148660170|ref|YP_001281693.1| membrane bound polyketide synthase Pks6 [Mycobacterium tuberculosis...
3.0E-74 [21..370] [599..922]
gi|15839791, gi|... - gi|15839791|ref|NP_334828.1| polyketide synthase [Mycobacterium tuberculosis CDC1551], gi|13879921|g...
3.0E-74 [21..370] [599..922]
gi|19572325|emb|... - StiH protein [Stigmatella aurantiaca]
gi|19572325 - gi|19572325|emb|CAD19092.1| StiH protein [Stigmatella aurantiaca]
4.0E-74 [21..381] [538..881]
gi|6563398 - gi|6563398|gb|AAF15892.2|AF204805_2 NosB [Nostoc sp. GSV224]
3.0E-73 [1..366] [508..834]
gi|29826958, gi|... - gi|29826958|ref|NP_821592.1| modular polyketide synthase [Streptomyces avermitilis MA-4680], gi|2960...
gi|15824141 - gi|15824141|dbj|BAB69305.1| modular polyketide synthase [Streptomyces avermitilis]
3.0E-71 [5..379] [528..862]

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Predicted Domain #1
Region A:
Residues: [1-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVLRKLEEN YRPLNILKMQ KVSSSYMAFF GRQGTSISIS ILKAIIRNKS REFQTILSQN  60
   61 GKESNDLLQY IFQNPSSPGS IAVCSNLFYQ LYQILSNPSD PQDQAPKNMT KIDSPDKKDN 120
  121 EQCYLLGHSL GELTCLSVNS LFSLKDLFDI ANFRNKLMVT STEKYLVAHN INRSNKFEMW 180
  181 ALSSPRATDL PQEVQKLLNS PNLLSSSQNT ISVANANSVK QCVVTGLVDD LESLRTELNL 240
  241 RFPRLRITEL TNPYNIPFHN STVLRPVQEP LYDYIWDILK KNGTHTLMEL NHPIIANLDG 300
  301 NISYYIHHAL DRFVKCSSRT VQFTMCYDTI NSGTPVEIDK SICFGPGNVI YNLIRRNCPQ 360
  361 VDTIEYTSLA TIDAYHKAAE ENKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.09691
Match: 1mla__
Description: Catalytic domain of malonyl-CoA ACP transacylase FabD; Probable ACP-binding domain of malonyl-CoA ACP transacylase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle