YRC Public Data Repository - Protein Structure Prediction

Protein:	THI72
Organism:	Saccharomyces cerevisiae
Length:	599 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THI72.

Description	E-value	Query Range	Subject Range
THI72_YEAST - Thiamine transporter THI72 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THI72 PE=2 SV... gi\|207341054 - gi\|207341054\|gb\|EDZ69218.1\| YOR192Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190407508 - gi\|190407508\|gb\|EDV10775.1\| thiamine transporter [Saccharomyces cerevisiae RM11-1a] THI72 - Transporter of thiamine or related compound; shares sequence similarity with Thi7p	0.0	[1..599]	[1..599]
YI26_SCHPO - Uncharacterized amino-acid permease P7G5.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... SPAP7G5.06 - amino acid permease, unknown 4	1.0E-83	[19..533]	[52..569]
gi\|68470470, gi\|... - gi\|68470731\|ref\|XP_720611.1\| N-acetylglucosamine-inducible general amino acid permease [Candida albi... gi\|18568390 - gi\|18568390\|gb\|AAL76065.1\| Gap1 protein [Candida albicans] gi\|238882678 - gi\|238882678\|gb\|EEQ46316.1\| general amino-acid permease GAP1 [Candida albicans WO-1]	4.0E-83	[37..540]	[70..572]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	6.0E-83	[2..503]	[70..578]

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Predicted Domain #1

Region A:
Residues: [1-547]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFGTRISRA LRFLEIPVKN RASVNFLRNP DLQPIKSVNQ TWGFWSNFAY WGVLSFNVGM  60
   61 WIGGSSALTV GLSYSETIGA FIIADLLTIL FALANSCPGY DWKVGFTLAQ RFVFGIYGSA 120
  121 LGIIIRILMS IVYYGSNAWL GGLCVNMILD SWSHHYLHLP NTLSSKVAMT TKELIGFIIF 180
  181 HILTAFCYFM KPYHMNYILI WSCVGTFFAM LGMVIYLTKS AHGVGDLFTS THSTVTGSKK 240
  241 AWAWVYTISY WYGSVSPGCT NQSDFSRFGS SNCAIWTGTI VALLIPATLI PVFGIIGASA 300
  301 CEKLYGQTFW MPMDIFDNWL TTNYSAGARA ATFFCGFCFV MSQISYTISN CGFASGMDLA 360
  361 GLLPKYVDIK RGAIFAACVS WACLPWNFYN SSSTFLTVMS SFGVVMTPII TVMICDNFLI 420
  421 RKRQYSVTNA FVLKGEYYFT KGVNWRAIVA WVCGMAPGLP GIAWEVNNDY FHNTGIINFF 480
  481 YGDSFFSFLI SFFVYWGLCL LFPFKITVKH DDKDYYGAFT DEEARKKGMV PYSEISEEEI 540
  541 RAYTLGE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	171.259637
Match:	PF02133
Description:	Permease for cytosine/purines, uracil, thiamine, allantoin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [548-599]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CFTSGHEYKP ESSDDELPEL TKTSSENTKV FEIVHQKDNE KESSTSSEKQ IA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits