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View Structure Prediction Details

Protein: MPC54
Organism: Saccharomyces cerevisiae
Length: 464 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPC54.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-49 [10..455] [196..663]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
1.0E-49 [10..455] [1185..1652]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
9.0E-49 [10..430] [1179..1621]
gi|4249701 - gi|4249701|gb|AAD13772.1| myosin heavy chain [Rana catesbeiana]
1.0E-48 [10..459] [68..536]

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Predicted Domain #1
Region A:
Residues: [1-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEDTSYSNS FEDYYNNSHA ISPYKDSFYK EMTPSKPNVR FGDDDVNIFD QRKKVNEINK  60
   61 NNTVKRSIPS SISTTITPNK SSLKSPRGKR ASKNSFDNET KLESKNETLK EVNDAVNRCY 120
  121 ALCNIPTKHV SINSISDLAQ TFETLAVGIT HETNRKAECE RSKNAIDSLY YHEQLEKKEL 180
  181 NEKSLQMAID HLLKVTKQNL RQADDGNKLK ETEALKSFIE EIEEVDDNKI SINSLQQQLL 240
  241 EEKTANNILR RDYYKLQERG RRLCHEFQEL QDDYSKQMKQ KEYEVQKLKN EIKVLLNMND 300
  301 NLKAEKAHYS QKEKQYFQKY TYIEKYMNHV KEEYNRKEDE CKKLNFIIDK SMKKIEHLER 360
  361 SLQTQFTAQN SFSTAMIQEE GPKDAHLKDR YHKVKEFMEQ KLQTSKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [408-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDPSCSEAEA LDNVLCLIES SMKTLDKNSK CYPIATKKCI KYVTDSPRLK ENEHVTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.500 a.4.5 "Winged helix" DNA-binding domain
View Download 0.547 a.4.1 Homeodomain-like
View Download 0.619 a.16.1 S15/NS1 RNA-binding domain
View Download 0.616 a.30.1 ROP protein
View Download 0.468 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.619 a.16.1 S15/NS1 RNA-binding domain
View Download 0.616 a.30.1 ROP protein
View Download 0.547 a.4.1 Homeodomain-like
View Download 0.500 a.4.5 "Winged helix" DNA-binding domain
View Download 0.481 a.4.1 Homeodomain-like
View Download 0.467 a.4.5 "Winged helix" DNA-binding domain
View Download 0.454 a.157.1 Skp1 dimerisation domain-like
View Download 0.449 a.2.7 tRNA-binding arm
View Download 0.444 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.436 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.427 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.421 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.417 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.413 g.2.2 Neurotoxin B-IV
View Download 0.397 a.4.1 Homeodomain-like
View Download 0.396 a.4.1 Homeodomain-like
View Download 0.393 a.4.1 Homeodomain-like
View Download 0.378 a.4.5 "Winged helix" DNA-binding domain
View Download 0.376 a.4.5 "Winged helix" DNA-binding domain
View Download 0.375 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.351 f.13.1 Family A G protein-coupled receptor-like
View Download 0.334 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.318 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.305 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.297 a.112.1 Description not found.
View Download 0.295 a.4.5 "Winged helix" DNA-binding domain
View Download 0.294 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.294 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.293 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.291 a.4.12 TrpR-like
View Download 0.281 a.4.1 Homeodomain-like
View Download 0.266 a.4.11 RNA polymerase subunit RPB10
View Download 0.265 a.4.1 Homeodomain-like
View Download 0.244 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.239 a.4.1 Homeodomain-like
View Download 0.237 f.15.1 Small-conductance potassium channel
View Download 0.232 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.230 a.7.6 Ribosomal protein S20
View Download 0.223 a.2.3 Chaperone J-domain
View Download 0.217 a.4.5 "Winged helix" DNA-binding domain
View Download 0.217 g.39.1 Glucocorticoid receptor-like (DNA-binding domain)
View Download 0.217 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.209 a.5.2 UBA-like
View Download 0.202 a.74.1 Cyclin-like


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