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View Structure Prediction Details

Protein: TMA46
Organism: Saccharomyces cerevisiae
Length: 401 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TMA46.

Description E-value Query
Range
Subject
Range
gi|6841256 - gi|6841256|gb|AAF28981.1|AF161421_1 HSPC303 [Homo sapiens]
0.0 [62..381] [44..363]
C3H21_ARATH - Zinc finger CCCH domain-containing protein 21 OS=Arabidopsis thaliana GN=At2g20280 PE=3 SV=1
1.0E-82 [57..337] [1..281]
gi|85080075 - gi|85080075|ref|XP_956473.1| hypothetical protein NCU01795 [Neurospora crassa OR74A]
gi|18376116, gi|... - gi|32415509|ref|XP_328234.1| hypothetical protein [Neurospora crassa], gi|28917539|gb|EAA27237.1| pr...
1.0E-81 [57..310] [1..265]
gi|1236259 - gi|1236259|dbj|BAA12184.1| unnamed protein product [Schizosaccharomyces pombe]
6.0E-68 [57..372] [1..283]
mep33 - mRNA export protein Mep33
MEP33_SCHPO - mRNA export protein 33 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mep33 PE=2 SV=1
3.0E-66 [57..372] [1..283]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-64 [61..372] [7..280]
gi|19171350, gi|... - gi|85014321|ref|XP_955656.1| hypothetical protein ECU09_1010 [Encephalitozoon cuniculi GB-M1], gi|19...
gi|19173224 - ref|NP_597027.1| hypothetical protein [Encephalitozoon cuniculi]
8.0E-49 [60..345] [6..226]

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Predicted Domain #1
Region A:
Residues: [1-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMKKFLFPS DELVKIDNIS FFNQCVLLFL ESKGSHSISK PLGFTHIKSQ ESYISKMPPK  60
   61 KGKQAQAAGK KKDNVDKTFG MKNKNRSTKV QKYIKQVQSQ SDPKKEEMRL KKLEEKKRRE 120
  121 AEEAERRALF NPVADQRVRA GVDPKSMVCA LFKLGNCNKG AKCKFSHDLN VGRRMEKKDL 180
  181 YQDTRSEKEN DTMDNWDEEK LRKVILSKHG NPKTTTDKVC KYFIEAVENG KYGWFWICPN 240
  241 GGDKCMYRHS LPEGFVLKTN EQKRLERESL EKQPKITLEE FIETERGKLD KSKLTPITIA 300
  301 NFAQWKKDHV IAKINAEKKL SSKRKPTGRE IILKMSAENK SFETDNADMP DDVTQGSAWD 360
  361 LTEFTDALKK ADHQDDGGIK DYGDGSNPTF DIKKANSATL A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [130-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNPVADQRVR AGVDPKSMVC ALFKLGNCNK GAKCKFSHDL NVGRRMEKKD LYQDTRSEKE  60
   61 NDTMDNWDEE KLRKVILSKH GNPKTTTDKV CKYFIEAVEN GKYGWFWICP NGGDKCMYRH 120
  121 SLPEGFVLKT NEQKRLERES LEKQPKITLE EFIETERGKL DKS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.64
Match: 2cqeA
Description: Solution Structure of the Zinc-finger domain in KIAA1064 protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [293-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLTPITIANF AQWKKDHVIA KINAEKKLSS KRKPTGREII LKMSAENKSF ETDNADMPDD  60
   61 VTQGSAWDLT EFTDALKKAD HQDDGGIKDY GDGSNPTFDI KKANSATLA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle