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View Structure Prediction Details

Protein: ASE1
Organism: Saccharomyces cerevisiae
Length: 885 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASE1.

Description E-value Query
Range
Subject
Range
ASE1 - Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for s...
ASE1_YEAST - Anaphase spindle elongation protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASE1...
8.0E-87 [1..885] [1..885]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
2.0E-76 [5..740] [1142..1898]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-76 [5..731] [158..905]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
2.0E-76 [5..731] [1147..1894]
MYH2_PIG - Myosin-2 OS=Sus scrofa GN=MYH2 PE=2 SV=1
gi|55741490 - ref|NP_999301.1| myosin heavy chain 2a [Sus scrofa]
2.0E-76 [5..731] [1143..1890]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
3.0E-76 [5..766] [1143..1925]
gi|8250661 - gi|8250661|gb|AAB29713.2| myosin heavy chain [Rattus sp.]
9.0E-76 [5..732] [96..844]

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Predicted Domain #1
Region A:
Residues: [1-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METATSSPLP IKSRRNSENS GSTTVIPHMN PSLATPLTVS TMVNQSNSKE FMKLTPVRIR  60
   61 DFGSPLKNVS TNYHFLDSEN GKGNTMDNMY RENFILISKD LEKLLENLNV IYQNIGYSNT 120
  121 EIITKEKIIF TTISNSIKQF FEQADEELKR LSAENGIEQD ILNNILERIN DPSGIKTIPD 180
  181 LYIRNAILLQ ESKTVPQSPK KPLSLLSKKA ALDTAKKFVL GSFLPRLRDY LKSLITLKHL 240
  241 IQSVKENLPG LTEADNEAIA EFPELSTLTA YLLQIENGKG DIGLSMKFII DNRKDILK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [299-746]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSAFKTINEE SVKHMNEVIK IYEEEYERRF KSVLTKKVSI SSICEQLGTP LATLIGEDFE  60
   61 QDLRSYGEEE NSTSEIPNFH PVDRERMSKI DITLEKLQAI HKERADKKRL LMEQCQKLWT 120
  121 RLKISQEYIK TFMRNNSSLS TESLGRISKE VMRLEAMKKK LIKKLISDSW DKIQELWRTL 180
  181 QYSEESRSKF IIVFEELRNS ATTLQEDELL LETCENELKR LEEKLTLYKP ILKLISDFES 240
  241 LQEDQEFLER SSKDSSRLLS RNSHKILLTE EKMRKRITRH FPRVINDLRI KLEEADGLFD 300
  301 QPFLFKGKPL SEAIDIQQQE IEAKYPRCRV RMQRSKKGKC GANKENKVIK NTFKATESSI 360
  361 RVPIGLNLND ANITYKTPSK KTIQGLTKND LSQENSLARH MQGTTKLSSP NRRATRLLAP 420
  421 TVISRNSKGN IERPTLNRNR SSDLSSSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [747-885]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RINHTHGEHA VKPRQLFPIP LNKVDTKGSH IPQLTKEKAL ELLKRSTGTT GKENVRSPER  60
   61 KSSLEDYAQK LSSPYKEPEH SIYKLSMSPE GKFQLNIQQK DIESGFDDTS MMEDENDKDF 120
  121 ITWKNEQVSK LNGFSFTDI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [737-885]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRSSDLSSSP RINHTHGEHA VKPRQLFPIP LNKVDTKGSH IPQLTKEKAL ELLKRSTGTT  60
   61 GKENVRSPER KSSLEDYAQK LSSPYKEPEH SIYKLSMSPE GKFQLNIQQK DIESGFDDTS 120
  121 MMEDENDKDF ITWKNEQVSK LNGFSFTDI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle