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View Structure Prediction Details

Protein: TIR4
Organism: Saccharomyces cerevisiae
Length: 487 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIR4.

Description E-value Query
Range
Subject
Range
ZAN_MOUSE - Zonadhesin OS=Mus musculus GN=Zan PE=1 SV=1
1.0E-55 [21..461] [545..1004]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
9.0E-52 [4..483] [619..1106]
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
7.0E-49 [30..477] [531..994]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
1.0E-48 [8..482] [838..1321]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYSKITLLA ALAAIAYAQT QAQINELNVV LDDVKTNIAD YITLSYTPNS GFSLDQMPAG  60
   61 IMDIAAQLVA NPSDDSYTTL YSEVDFSAVE HMLTMVPWYS SRLLPELEAM DASLTTSSSA 120
  121 ATS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 36.823909
Match: PF00660
Description: Seripauperin and TIP1 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [124-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSEVASSSIA SSTSSSVAPS SSEVVSSSVA PSSSEVVSSS VAPSSSEVVS SSVASSSSEV  60
   61 ASSSVAPSSS EVVSSSVASS SSEVASSSVA PSSSEVVSSS VAPSSSEVVS SSVASSSSEV 120
  121 ASSSVAPSSS EVVSSSVASS TSEATSSSAV TSSSAVSSST ESVSSSSVSS SSAVSSSEAV 180
  181 SSSPVSSVVS SSAGPASSSV APYNSTIASS SSTAQTSIST IAPYNSTTTT TPASSASSVI 240
  241 ISTRNGTTVT ETDNTLVTKE TTVCDYSSTS AVPASTTGYN NSTKVSTATI CSTCKEGTST 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.03
Match: 1ei3A
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [424-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATDFSTLKTT VTVCDSACQA KKSATVVSVQ SKTTGIVEQT ENGAAKAVIG MGAGALAAVA  60
   61 AMLL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.23
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [385-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVCDYSSTSA VPASTTGYNN STKVSTATIC STCKEGTSTA TDFSTLKTTV TVCDSACQAK  60
   61 KSATVVSVQS KTTGIVEQTE NGAAKAVIGM GAGALAAVAA MLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle