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View Structure Prediction Details

Protein: RTC1
Organism: Saccharomyces cerevisiae
Length: 1341 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RTC1.

Description E-value Query
Range
Subject
Range
RTC1 - Protein of unknown function; may interact with ribosomes, based on co-purification experiments; null...
0.0 [1..1341] [1..1341]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [27..714] [858..1493]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [61..597] [819..1316]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSPHVENA SIPKGSTPIP KNRNVSSIGK GEFLGSSSSN NSSFRMNHYS NSGQPSVLDS  60
   61 IRRPNLTPTF SYSNGVYMPE SHRTSSFNDS YLPYDKNPYA KTTGSMSNKS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1c5kA_
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [111-438]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMKIKTKKNA INTNTRKSSG LIYTTKVDKE LSSIDKVNDP NINGLVCAGK THLGLYKFSP  60
   61 SDRSIKCVHD FITPNSNTST RGTTSLLPKL SKRTRQNKFS TIADVKTGFN NYKNCIAVCN 120
  121 NSTAISIYDL NKSSSIDNPL ITSLCEHTRS INSFDFNMVE SNLIISGGQD SCVKIWDLRS 180
  181 NKSKSSNRSD ISINTASDSI RDVKWMPGYN FASKNDQGSS TYGNLKSGYK FASIHDSGYL 240
  241 LKFDLRQPAQ YEKKLNAHTG PGLCLNWHPN QEYIATGGRD GKSCLWFVGD NANAAENTVL 300
  301 NYGNSPSLHA PNTSLNNSGS LAFPKLTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.39794
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [439-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTGYPVTKLK FKPAYSSNIY NSLLGISSMG DEAEVRIYSL ARKYIPKHVL LSETPSLGLV  60
   61 WWDENLIFNI DKGTRINGWD INKEPTVLEN LSKNTTTWRD LDGNGLLSVG QEIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.154902
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [553-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYEVVEPELQ PTSSTTCKKH PGTIKNPKNG NPENQGIIGG IKKGFSHTGL TSFTPERPPT  60
   61 LKAGPTFSTK SLTLASGASS FNSSSASLTS LTPQTENREE IAIEPPCIIT LDIPQIFNNI 120
  121 RLTKIAHSRK KNVISESSSM KNSPVEKFKY LARQLKFSYI REH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [716-1129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVSDSADTAY KNDIENIDVV KNATETHGDN TTTTNNNDDG DDDDDDDDDD KIIESHLLKK  60
   61 YNFPENNTWA TLMNEKVNNK KSKRNSSSSR EFDEKDVRSS ISSISASRQS HDRARKIDKN 120
  121 VEAELQEKIQ TLVDLISIAT HNASVYLSID DLTNFKIWIL IRDSLLWDLK WMTSSQISSD 180
  181 NASNMDANES SDFEAGENLK TGKEFPEEDG AGTSGAESLV EERPQAFRAN SDEPSDAEKK 240
  241 PVSKLKEQLK NTEIIPYAQP NEDSDEVLTK LKELQNQRLE SRTKMGETVS DDVIIEEDEH 300
  301 EHQEEEQPHD SPTKSAQFHA SPIAKSIPIL QKREHRKSFI DTFMLHSPNG YNGDTDIGNE 360
  361 DDNISPRFTY NSVSPRSKVS SLQSYATTTS QLETFKKLSS HTAPIIGSPR HAPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1130-1341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPDSIGREQL SSSLTKKLAK CKKIIADPPW DTKKLIKQLY NQATETGNVV LTVNILFLFQ  60
   61 TIYQITEIDI AKDAIAHFLL LLHRYELFGI AADVLKYCPF EDIMGSEGDQ SSIRLFCERC 120
  121 GELITNESSK EKLRAEAQQT GNKKIMDKFG YWYCDSCKKK NTSCVLCERP LKKLTMVILP 180
  181 CGHEGHFQCI QEWFLDENEQ ECPGGCPGVA FI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1122-1227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSPRHAPSRP DSIGREQLSS SLTKKLAKCK KIIADPPWDT KKLIKQLYNQ ATETGNVVLT  60
   61 VNILFLFQTI YQITEIDIAK DAIAHFLLLL HRYELFGIAA DVLKYC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1228-1341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFEDIMGSEG DQSSIRLFCE RCGELITNES SKEKLRAEAQ QTGNKKIMDK FGYWYCDSCK  60
   61 KKNTSCVLCE RPLKKLTMVI LPCGHEGHFQ CIQEWFLDEN EQECPGGCPG VAFI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 2jm1A
Description: No description for 2jm1A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle