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View Structure Prediction Details

Protein: TRM13
Organism: Saccharomyces cerevisiae
Length: 476 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRM13.

Description E-value Query
Range
Subject
Range
gi|190407227 - gi|190407227|gb|EDV10494.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
TRM13_YEAST - tRNA:m(4)X modification enzyme TRM13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRM...
gi|151945510 - gi|151945510|gb|EDN63751.1| tRNA 2'-O-methyltransferase [Saccharomyces cerevisiae YJM789]
TRM13 - 2'-O-methyltransferase responsible for modification of tRNA at position 4; C-terminal domain has sim...
0.0 [1..476] [1..476]
gi|7023747, gi|5... - gi|7023747|dbj|BAA92074.1| unnamed protein product [Homo sapiens], gi|50370008|gb|AAH75811.1| Coiled...
0.0 [20..474] [18..470]
TRM13_SCHPO - tRNA guanosine-2'-O-methyltransferase trm13 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
trm13 - tRNA 2'-O-methyltransferase Trm13
0.0 [49..476] [32..405]
CE22211 - status:Confirmed UniProt:Q9XW93 protein_id:CAA22074.1
0.0 [21..475] [16..390]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQDNNGPAV KRAKPSERLQ CEYFMEKKKR RCGMTRSSQN LYCSEHLNLM KKAANSQVHN  60
   61 KNGSEAEKER ERVPCPLDPN HTVWADQLKK HLKKCNKTKL SHLNDDKPYY EPGYNGENGL 120
  121 LSSSVKIDIT AEHLVQSIEL LYKVFEGESM DELPLRQLNN KLMSLKRFPQ LPSNTKHAVQ 180
  181 QSSLIENLVD AGAFERPESL NFIEFGCGRA EFSRYVSLYL LTQLTSLP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [229-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEHSGSNSNE FVLIDRATNR MKFDKKIKDD FSEIKSNSPS KPISCPSIKR IKIDIRDLKM  60
   61 DPILKSTPGD DIQYVCISKH LCGVATDLTL RCIGNSSILH GDDNNGCNPK LKAICIAMCC 120
  121 RHVCDYGDYV NRSYVTSLVE KYRAHGSILT YETFFRVLTK LCSWGTCGRK PGTAITDIVN 180
  181 VVESFEGAEP YTITIKEREN IGLMARRVID EGRLVYVKEK FTEFNAELIR YVESDVSLEN 240
  241 VAMLVYKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [309-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LCGVATDLTL RCIGNSSILH GDDNNGCNPK LKAICIAMCC RHVCD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.996
Match: 1iglA
Description: SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [354-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGDYVNRSYV TSLVEKYRAH GSILTYETFF RVLTKLCSWG TCGRKPGTAI TDIVNVVESF  60
   61 EGAEPYTITI KERENIGLMA RRVIDEGRLV YVKEKFTEFN AELIRYVESD VSLENVAMLV 120
  121 YKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle