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View Structure Prediction Details

Protein: SMF1
Organism: Saccharomyces cerevisiae
Length: 575 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMF1.

Description E-value Query
Range
Subject
Range
SMF1_YEAST - Manganese transporter SMF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SMF1 PE=1 SV=...
SMF1 - Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-tr...
0.0 [1..575] [1..575]
gi|4433391 - gi|4433391|gb|AAD20722.1| natural resistance associated macrophage protein-beta [Oncorhynchus mykiss...
0.0 [24..496] [6..467]
gi|6273404 - gi|6273404|emb|CAB60196.1| putative natural resistance-associated macrophage protein [Cyprinus carpi...
0.0 [38..496] [15..461]
NRAM2_MOUSE - Natural resistance-associated macrophage protein 2 OS=Mus musculus GN=Slc11a2 PE=1 SV=2
0.0 [41..496] [29..473]
gi|57164361, gi|... - gi|57164361|ref|NP_001009345.1| natural resistance associated macrophage protein [Ovis aries], gi|40...
0.0 [44..496] [40..482]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNVGPSHAA VAVDASEARK RNISEEVFEL RDKKDSTVVI EGEAPVRTFT SSSSNHERED  60
   61 TYVSKRQVMR DIFAKYLKFI GPGLMVSVAY IDPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.667 a.64.1 Saposin
View Download 0.560 a.47.2 t-snare proteins
View Download 0.557 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.604 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.463 d.58.19 Bacterial exopeptidase dimerisation domain
View Download 0.460 c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.459 d.94.1 HPr-like
View Download 0.443 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.440 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.396 d.93.1 SH2 domain
View Download 0.391 d.58.5 GlnB-like
View Download 0.382 d.52.4 YhbC-like, N-terminal domain
View Download 0.367 a.7.7 BAG domain
View Download 0.365 d.80.1 Tautomerase/MIF
View Download 0.357 a.6.1 Putative DNA-binding domain
View Download 0.357 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.351 d.141.1 Ribosomal protein L6
View Download 0.345 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.345 c.52.1 Restriction endonuclease-like
View Download 0.337 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.331 d.101.1 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
View Download 0.324 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.313 d.53.1 Ribosomal protein S3 C-terminal domain
View Download 0.313 d.66.1 Alpha-L RNA-binding motif
View Download 0.313 a.60.2 RuvA domain 2-like
View Download 0.311 a.142.1 PTS-regulatory domain, PRD
View Download 0.309 a.7.1 Spectrin repeat
View Download 0.298 d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.293 d.57.1 DNA damage-inducible protein DinI
View Download 0.291 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.283 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.277 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.273 a.60.1 SAM/Pointed domain
View Download 0.269 d.13.1 HIT-like
View Download 0.268 d.58.5 GlnB-like
View Download 0.259 b.6.1 Cupredoxins
View Download 0.259 d.26.1 FKBP-like
View Download 0.249 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.245 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.244 a.7.1 Spectrin repeat
View Download 0.242 a.60.1 SAM/Pointed domain
View Download 0.240 a.64.1 Saposin
View Download 0.237 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.235 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.223 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.223 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.221 a.7.8 GAT domain
View Download 0.220 c.49.1 Pyruvate kinase, C-terminal domain
View Download 0.219 a.4.3 ARID-like
View Download 0.218 a.39.3 Cloroperoxidase
View Download 0.213 f.17.1 F1F0 ATP synthase subunit C
View Download 0.213 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.211 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.209 a.24.11 Bacterial GAP domain
View Download 0.208 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.208 a.1.1 Globin-like
View Download 0.208 a.4.5 "Winged helix" DNA-binding domain
View Download 0.204 a.29.2 Bromodomain

Predicted Domain #2
Region A:
Residues: [95-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYSTAVDAGA SNQFSLLCII LLSNFIAIFL QCLCIKLGSV TGLDLSRACR EYLPRWLNWT  60
   61 LYFFAECAVI ATDIAEVIGT AIALNILIKV PLPAGVAITV VDVFLIMFTY KPGASSIRFI 120
  121 RIFECFVAVL VVGVCICFAI ELAYIPKSTS VKQVFRGFVP SAQMFDHNGI YTAISILGAT 180
  181 VMPHSLFLGS ALVQPRLLDY DVKHGNYTVS EEQDKVKKSK STEEIMEEKY FNYRPTNAAI 240
  241 KYCMKYSMVE LSITLFTLAL FVNCAILVVA GSTLYNSPEA DGADLFTIHE LLSRNLAPAA 300
  301 GTIFMLALLL SGQSAGVVCT MSGQIVSEGH INWKLQPWQR RLATRCISII PCLVISICIG 360
  361 REALSKALNA SQVVLSIVLP FLVAPLIFFT CKKSIMKTEI TVDHTEEDSH NH

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 245.60206
Match: PF01566
Description: Natural resistance-associated macrophage protein

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [507-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNNNDRSAGS VIEQDGSSGM EIENGKDVKI VYMANNWIIT VIAIIVWLFL SLLNVYAIVQ  60
   61 LGMSHGDIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.351 a.4.1 Homeodomain-like
View Download 0.539 g.7.1 Snake toxin-like
View Download 0.377 d.15.7 Immunoglobulin-binding domains
View Download 0.369 d.10.1 DNA-binding domain
View Download 0.284 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.276 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.244 b.84.2 Rudiment single hybrid motif
View Download 0.232 d.58.4 Dimeric alpha+beta barrel
View Download 0.218 g.44.1 RING/U-box


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle