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View Structure Prediction Details

Protein: ITR2
Organism: Saccharomyces cerevisiae
Length: 612 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ITR2.

Description E-value Query
Range
Subject
Range
gi|218437 - gi|218437|dbj|BAA14366.1| ITR1 [Saccharomyces cerevisiae]
0.0 [35..611] [9..582]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
0.0 [66..608] [14..563]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [43..608] [1..564]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEMKNSTAA SSRWTKSRLS HFFPSYTNSS GMGAASTDQS STQGEELHHR KHCEEDNDGQ  60
   61 KPKKSPVSTS TMQIKSRQDE DEDDGRIVIK PVN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.229 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.429 a.24.17 Group V grass pollen allergen
View Download 0.259 a.51.1 Cytochrome c oxidase subunit h
View Download 0.250 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region

Predicted Domain #2
Region A:
Residues: [94-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEDDTSVIIT FNQSISPFII TLTFVASISG FMFGYDTGYI SSALISINRD LDNKVLTYGE  60
   61 KELITAATSL GALITSVGAG TAADVFGRRP CLMFSNLMFL IGAILQITAH KFWQMAAGRL 120
  121 IMGFGVGIGS LISPLFISEI APKMIRGRLT VINSLWLTGG QLIAYGCGAG LNHVKNGWRI 180
  181 LVGLSLIPTV LQFSFFCFLP 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [341-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNPITKFWNM VKELHTVPSN FRALIIGCGL QAIQQFTGWN SLMYFSGTIF ETVGFKNSSA  60
   61 VSIIVSGTNF VFTLIAFFCI DKIGRRYILL IGLPGMTVAL VICAIAFHFL GIKFNGADAV 120
  121 VASDGFSSWG IVIIVFIIVY AAFYALGIGT VPWQQSELFP QNVRGVGTSY ATATNWAGSL 180
  181 VIASTFLTML QNITPTGTFS FFAGVACLST IFCYFCYPEL S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 521.9794
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #3
Region A:
Residues: [294-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTPRYYVMKG DLKRAKMVLK RSYVNTEDEI IDQKVEELSS LNQSIPG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [562-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLELEEVQTI LKDGFNIKAS KALAKKRKQQ VAEGAAHHKL KFEPTQEIVE S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 521.9794
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle