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View Structure Prediction Details

Protein: APM4
Organism: Saccharomyces cerevisiae
Length: 491 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APM4.

Description E-value Query
Range		 Subject
Range
gi|149757264 - gi|149757264|ref|XP_001502865.1| PREDICTED: similar to adaptor-related protein complex 1, mu 1 subun...
AP1M1 - adaptor-related protein complex 1, mu 1 subunit
gi|109123796 - gi|109123796|ref|XP_001112653.1| PREDICTED: similar to adaptor-related protein complex 1, mu 1 subun...
gi|114675917, gi... - gi|114675917|ref|XP_001172777.1| PREDICTED: adaptor-related protein complex 1, mu 1 subunit isoform ...
gi|73986080 - gi|73986080|ref|XP_852486.1| PREDICTED: similar to adaptor-related protein complex 1, mu 1 subunit i...
AP1M1_BOVIN - AP-1 complex subunit mu-1 OS=Bos taurus GN=AP1M1 PE=1 SV=3
 0.0 [2..490] [3..421]
gi|55249923 - gb|AAH86151.1| Unknown (protein for MGC:98582) [Xenopus laevis]
AP1M1_MOUSE - AP-1 complex subunit mu-1 OS=Mus musculus GN=Ap1m1 PE=1 SV=3
 0.0 [2..490] [3..421]
APM4 - Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport
AP2M_YEAST - AP-2 complex subunit mu OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APM4 PE=1 SV=1
 0.0 [1..491] [1..491]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [1..490] [1..434]
AP1M2_ARATH - AP-1 complex subunit mu-2 OS=Arabidopsis thaliana GN=AP1M2 PE=1 SV=1
 0.0 [2..490] [5..426]
gi|12000357 - gi|12000357|gb|AAG11391.1| clathrin-adaptor medium chain apm 1 [Dictyostelium discoideum]
 0.0 [2..490] [3..426]

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Predicted Domain #1
Region A:
Residues: [1-179] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISGVLVYSS RGELVLNKFF KNSLKRSISD IFRVQVINNL DVRSPVLTLG STTFHHIRSR  60
   61 HGDNLWLVTI TRSNANSAAI WEFLYKLDAV MNAYRLDREE ALKEEFMIVH EMLDIMLGGN 120
  121 GIPIDTELNS VIAQMSVKPV RNMGGLLDSP DGNDVLSSSS SPTSSAGELH FPKFLTKRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 842.9794
Match: 1gw5M_
Description: Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [180-491] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSFLGQGDST SDFYDNNKIT WRPKGIIHKK DEVFLYVNER INILVSRDGS ILKSYVDGTI  60
   61 DITTHLSGTP ICRFGLNDSL GMQSEDEKKW LAQQQRHSGS DFGNKNFIPK AAAGSVLLED 120
  121 CKFHECVSLD KFNRNHIIEF VPPDGSMELM KYHVRDNINL PFKVTPIVTH STRDNEIDYR 180
  181 ITLKSLFPGK LSAKDVVLHI PVPPSTVDCK ISVSNGHCKF VPEENAMIWR FNKYNGLTEN 240
  241 TLSAVTVSTS DTTQLNLQQW TRPPISLEFE VMMFSNSGLV VRYFTISGKD SKHRAVKWIK 300
  301 YISKAGSYEV RY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 842.9794
Match: 1gw5M_
Description: Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle