YRC Public Data Repository - Protein Structure Prediction

Protein:	MDM38
Organism:	Saccharomyces cerevisiae
Length:	573 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDM38.

Description	E-value	Query Range	Subject Range
MDM38_YEAST - Mitochondrial distribution and morphology protein 38 OS=Saccharomyces cerevisiae (strain ATCC 204508... MDM38 - Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial ...	0.0	[1..573]	[1..573]
LETM1_MOUSE - LETM1 and EF-hand domain-containing protein 1, mitochondrial OS=Mus musculus GN=Letm1 PE=1 SV=1	2.0E-99	[31..546]	[100..633]
LETM1 - leucine zipper-EF-hand containing transmembrane protein 1 gi\|123993861 - gi\|123993861\|gb\|ABM84532.1\| leucine zipper-EF-hand containing transmembrane protein 1 [synthetic con...	4.0E-98	[31..543]	[101..631]
letm-1 - Yeast cosmid 9642 hypothetical protein like status:Confirmed UniProt:Q9XVM0 protein_id:CAB03150.1	1.0E-75	[2..529]	[3..537]
MDM28_SCHPO - LETM1 domain-containing protein mdm28, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC... SPAC23C11.17 - mitochondrial inner membrane protein involved in potassium ion transport	1.0E-73	[25..481]	[53..485]
gi\|15232180, gi\|... - gi\|7019676\|emb\|CAB75801.1\| putative protein [Arabidopsis thaliana], gi\|15232180\|ref\|NP_191541.1\| cal...	5.0E-69	[66..366]	[187..483]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNFASRASC VTRRQASLYF VKNQGPRLIA STIPSCHWPL RAQGVQPNYP LSLRFYSTDK  60
   61 SKSVTKPVAP TSTDAPAKPK ETLMVKVKHA LKHYANGTKL LGYEIKVSTK LLIKFAQGYE 120
  121 LSRRERNQLR RTMGDVFRLI PFSAFLIIPF AELFLPFALK LFPNLLPSTY ESGKDKQAKR 180
  181 NKLIEIRKKT SEFLHETLEE SNLITYNTIE NAEKKQKFLN FFRKLYSAK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [230-386]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGKIMTFQHD EISAIAQMFK NDSVLDNLSR PQLAAMSKFM SLRPFGNDNM LRYQIRSKLK  60
   61 DIMNDDKTID YEGVESLSQE ELYQACVSRG MKAYGVSKED LVDNLKVWLE LRLRQKIPSV 120
  121 LMVLSSTFTF GGLPKENYSK AFSPLAEKKE TKSKYDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.154902
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [387-573]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLDLYYDGIL QVLSSIPDPV YNVAKLDVSE SKSSAAETEA EKQVAEKKIK TEEKPEETAI  60
   61 PKEEATAKES VIATTASAVT PKLVVVNEKA ETAKTEEISQ EKENAEPTDS AEATEAEEKK 120
  121 TSDDNEFKLN VLKEQEELIK KEEEEAKQRA SREHVPDDIN LDEEEEAKSV PPIPADQAAK 180
  181 TFVIKKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.154902
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits