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View Structure Prediction Details

Protein: YNR066C
Organism: Saccharomyces cerevisiae
Length: 436 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNR066C.

Description E-value Query
Range
Subject
Range
YN95_YEAST - Uncharacterized membrane glycoprotein YNR066C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
YNR066C - Putative membrane-localized protein of unknown function
0.0 [1..436] [1..436]
gi|18032275 - gi|18032275|gb|AAL56667.1|AF284756_1 VPS10 domain receptor SorCS [Homo sapiens]
6.0E-98 [26..432] [176..528]
SORC1_MOUSE - VPS10 domain-containing receptor SorCS1 OS=Mus musculus GN=Sorcs1 PE=1 SV=1
1.0E-94 [26..432] [176..528]

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Predicted Domain #1
Region A:
Residues: [1-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILLQVICTI WTCLFIPLLN AEEFVPKVTE TLSEYSFSLE SFDDSNSLIR LDNQVVWISS  60
   61 DSGENWEAVK EIEGHILELI VDPLHGQDRA FVSIHLSPKF YVTDDRGKSW RALTIPVSEN 120
  121 CRLGTSCSIA THPTDKKYLI ADCPCFINDN GYIQIQNETY FTNDGESFYN IEPSLKKKED 180
  181 DHITSSSCNF VKSSKDSDIE GNDASILCLF SNHGYDSDRH LSAAYTQLAL STDGGKTFKK 240
  241 FDEFNDKIIY QYKILKSHII VSTQDDRYNE MSPMDIWISN DASTFQKARL PAQVRHVHMY 300
  301 GIYEDSIGRI IIPISTIFTD EKNDQPAPSE ILISDSQGLK FLPVEWTINP HFGYIDIASP 360
  361 HFLEGTIIGS FHPSFDYSHN KGKYNKKIAR YETKISVDNG LTWSNLKVVD EENADSFPCD 420
  421 ITRPERCSLQ NPFYSI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1mz5A
Description: Trypanosoma sialidase, C-terminal domain; Trypanosoma sialidase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [216-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSDRHLSAAY TQLALSTDGG KTFKKFDEFN DKIIYQYKIL KSHIIVSTQD DRYNEMSPMD  60
   61 IWISNDASTF QKARLPAQVR HVHMYGIYED SIGRIIIPIS TIFTDEKNDQ PAPSEILISD 120
  121 SQGLKFLPVE WTINPHFGYI DIASPHFLEG TIIGSFHPSF DYSHNKGKYN KKIARYETKI 180
  181 SVDNGLTWSN LKVVDEENAD SFPCDITRPE RCSLQNPFYS I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.26
Match: 1eurA
Description: SIALIDASE
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle