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View Structure Prediction Details

Protein: ZRG17
Organism: Saccharomyces cerevisiae
Length: 605 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZRG17.

Description E-value Query
Range
Subject
Range
ZRG17 - Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc...
ZRG17_YEAST - Protein ZRG17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ZRG17 PE=1 SV=1
0.0 [1..605] [1..605]
ZRG17_SCHPO - Probable zinc transporter zrg17 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=zrg17 PE=1...
SPBC16E9.14c - membrane transporter
4.0E-86 [146..354] [9..212]

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Predicted Domain #1
Region A:
Residues: [1-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METPQMNAIQ EEDNLSPEVA FQTPKLNDSD ASSFSLSNMN AVGNVDGIPS QNRTFFASPR  60
   61 PSSLFYSAKE GNNSSSSIIY NPSFTFGENA SSNANINEAA LMKGKGNEGR RQSLKYIPAP 120
  121 KLVPPPPRTR SPVRGIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [138-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDAGSSKRSS MTLDSPFNFT TSTLQPHQQT PPSSAASRTS FRKGHRYKHS SVSMNFFQEP  60
   61 EVKIPLNIAK SLPIPDFNDL LSNLPWPKAY IQLSIAALQI FACLITFQVG HLYSWSNFIT 120
  121 LSHFITYDII GSLVIIFVEN LSQFQVWFTG TITFPFGLNR IDVLLSFALA VSLCFVGLDL 180
  181 LFHIIEEFIV LFVESGSSLT NNHDHDEINE QIPHSHIAN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
cation transmembrane transporter activity 4.66797577217092 bayes_pls_golite062009
ion transmembrane transporter activity 4.59426322530417 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.22757882358966 bayes_pls_golite062009
transporter activity 2.72875628342635 bayes_pls_golite062009
transmembrane transporter activity 2.5812016552653 bayes_pls_golite062009
substrate-specific transporter activity 2.42221734489039 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 1.51622356320367 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.20045998574251 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 1.06864285262933 bayes_pls_golite062009
binding 1.0333257243016 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.683534503198654 bayes_pls_golite062009
efflux transmembrane transporter activity 0.556703621451116 bayes_pls_golite062009
cation channel activity 0.258076515880771 bayes_pls_golite062009
iron ion transmembrane transporter activity 0.186398867523746 bayes_pls_golite062009
protein binding 0.0991944030928594 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [357-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANDSQNENIT LWYSILMINL VLSTLSLYKT FYANKYSNLK TKNPIITITY TAYLFIYPLL  60
   61 LDLLSSISDY LATLVISSLI LWHGLTIARW TSTVLLMGFS TTSLSNSALF NNNDSTDTTA 120
  121 HTQQVESKAA KEKPSVRPRS MSSLPIATKN TKIRKTGFLN SAGFTENPTT IKNMIKDQIE 180
  181 RLSEFKSRYI LNYDDIVISK VNFTLYVVLI KITMKGGSDD DELMLRLAID KCIQTSIPTC 240
  241 ETTIDIDRI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle