YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM23
Organism:	Saccharomyces cerevisiae
Length:	222 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM23.

Description	E-value	Query Range	Subject Range
TIM23 - Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved... gi\|190408984 - gi\|190408984\|gb\|EDV12249.1\| 23 kDa mitochondrial inner membrane protein [Saccharomyces cerevisiae RM... gi\|151944545 - gi\|151944545\|gb\|EDN62823.1\| mitochondrial assembly-related protein [Saccharomyces cerevisiae YJM789] TIM23_YEAST - Mitochondrial import inner membrane translocase subunit TIM23 OS=Saccharomyces cerevisiae (strain AT...	2.0E-58	[1..222]	[1..222]
TIM23_SCHPO - Mitochondrial import inner membrane translocase subunit tim23 OS=Schizosaccharomyces pombe (strain 9... tim23 - mitochondrial inner membrane presequence translocase complex subunit Tim23	2.0E-53	[1..222]	[1..208]
CE15854 - status:Confirmed UniProt:Q9XVQ2 protein_id:CAB02956.1	2.0E-43	[1..222]	[1..234]
gi\|6760457 - gi\|6760457\|gb\|AAF28360.1\|AF223951_1 TIM22 preprotein translocase [Rattus norvegicus]	1.0E-40	[35..211]	[1..184]
gi\|28918346, gi\|... - gi\|32403688\|ref\|XP_322457.1\| hypothetical protein ( (AF343071) TIM23 [Neurospora crassa] ), gi\|28918... gi\|85084169 - gi\|85084169\|ref\|XP_957257.1\| mitochondrial import inner membrane translocase subunit tim23 [Neurospo...	4.0E-40	[7..219]	[10..228]
TI231_ARATH - Mitochondrial import inner membrane translocase subunit TIM23-1 OS=Arabidopsis thaliana GN=TIM23-1 P...	2.0E-39	[50..197]	[10..159]
gi\|53733686 - gb\|AAH84024.1\| Unknown (protein for MGC:98207) [Xenopus laevis] TIM22_MOUSE - Mitochondrial import inner membrane translocase subunit Tim22 OS=Mus musculus GN=Timm22 PE=1 SV=1	2.0E-37	[31..211]	[1..188]

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Predicted Domain #1

Region A:
Residues: [1-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWLFGDKTP TDDANAAVGG QDTTKPKELS LKQSLGFEPN INNIISGPGG MHVDTARLHP  60
   61 LAGLDKGVEY LDLEEEQLSS LEGSQGLIPS RGWTDDLCYG TGAVYLLGLG IGGFSGMMQG 120
  121 LQNIPPNSPG KLQLNTVLNH ITKRGPFLGN NAGILALSYN IINSTIDALR GKHDTAGSIG 180
  181 AGALTGALFK SSKGLKPMGY SSAMVAAACA VWCSVKKRLL EK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits