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View Structure Prediction Details

Protein: MRPL17
Organism: Saccharomyces cerevisiae
Length: 281 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPL17.

Description E-value Query
Range
Subject
Range
gi|190409226 - gi|190409226|gb|EDV12491.1| 60S ribosomal protein L17, mitochondrial precursor [Saccharomyces cerevi...
MRPL17 - Mitochondrial ribosomal protein of the large subunit
RM17_YEAST - 54S ribosomal protein L17, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
1.0E-96 [1..281] [1..281]
MRPL46 - mitochondrial ribosomal protein L46
2.0E-77 [9..280] [30..278]
mrpl17 - mitochondrial ribosomal protein subunit L17
RM17_SCHPO - 54S ribosomal protein L17, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=m...
1.0E-72 [2..280] [17..266]
RM46_MOUSE - 39S ribosomal protein L46, mitochondrial OS=Mus musculus GN=Mrpl46 PE=1 SV=1
7.0E-68 [9..281] [28..277]
gi|220947842, gi... - gi|220957220|gb|ACL91153.1| mRpL46-PA [synthetic construct], gi|220947842|gb|ACL86464.1| mRpL46-PA [...
mRpL46-PA - The gene mitochondrial ribosomal protein L46 is referred to in FlyBase by the symbol Dmel\mRpL46 (CG...
2.0E-59 [9..279] [11..258]
gi|24111323, gi|... - gi|24111323|gb|AAN46785.1| At1g14620/T5E21_15 [Arabidopsis thaliana], gi|22022540|gb|AAM83228.1| At1...
5.0E-47 [124..273] [69..229]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVNLMLKRG LATATATASS APPKIKVGVL LSRIPIIKSE LNELEKKYYE YQSELEKRLM  60
   61 WTFPAYFYFK KGTVAEHKFL SLQKGPISKK NGIWFPRGIP DIKHGRERST KQEVKLSDDS 120
  121 TVAFSNNQKE QSKDDVNRPV IPN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [144-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRITEADRSN DMKSLERQLS RTLYLLVKDK SGTWKFPNFD LSDESKPLHV HAENELKLLS  60
   61 GDQIYTWSVS ATPIGVLQDE RNRTAEFIVK SHILAGKFDL VASKNDAFED FAWLTKGEIS 120
  121 EYVPKDYFNK TEFLLADN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.74
Match: 1kt9A
Description: Diadenosine tetraphosphate hydrolase (Ap4A hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.38338559299412 bayes_pls_golite062009
binding 0.881558273069274 bayes_pls_golite062009
nucleic acid binding 0.495924061190848 bayes_pls_golite062009
RNA binding 0.44030858339937 bayes_pls_golite062009
protein binding 0.358912650308843 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle