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View Structure Prediction Details

Protein: NSG2
Organism: Saccharomyces cerevisiae
Length: 299 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NSG2.

Description E-value Query
Range
Subject
Range
NSG2_YEAST - Protein NSG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NSG2 PE=1 SV=1
NSG2 - Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG...
0.0 [1..299] [1..299]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANRGEPDPK KSTESICSLT KPQLYSLYDD DVVRSEDNEI YEELKRSVSI DSTKYSRDQT  60
   61 IDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.293 a.60.2 RuvA domain 2-like
View Download 0.471 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.442 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.442 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.294 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.290 a.4.1 Homeodomain-like
View Download 0.263 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.234 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.222 d.192.1 YlxR-like
View Download 0.209 a.23.5 Hemolysin expression modulating protein HHA

Predicted Domain #2
Region A:
Residues: [64-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFYLAHKVGG SLPRNTVSSN NLERILSASS IHENFPSRTR QTRQNILHYL QAVLILSLSG  60
   61 FAYHELSRNL HDNHLLHPDF ASRPLLLGVK LCNWLSNGVL PNWLGYGVEG LLFGSVVPIL 120
  121 DNIFQTEVVK SSVHHDSLTS VIRSINAMLG VTFGIRKIQW NSSLQAAGAW GLLNIILWLF 180
  181 FDGSISMLMS CICIGVGCCI SCYKDIIDGS QFLYFMDFYF LGSLMFGKLG RYLYSH

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.18
Match: 1jfaA
Description: Trichodiene synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle