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View Structure Prediction Details

Protein: MET4
Organism: Saccharomyces cerevisiae
Length: 672 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MET4.

Description E-value Query
Range
Subject
Range
MET4 - Leucine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pa...
MET4_YEAST - Transcriptional activator of sulfur metabolism MET4 OS=Saccharomyces cerevisiae (strain ATCC 204508 ...
0.0 [1..672] [1..672]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQEQSHEGD SYSTEFINLF GKDTATHPSS NNGANNNGMG STNSLDQFVA TASSSSSLVT  60
   61 SSENRRPLIG DVTNRGNTNL YDHAVTPEIL LEQLAYVDNF IPSLDNEFSN VDWNVNTTHN 120
  121 NANNNGADTF SSINANPFDL DEQLAIELSA FADDSFIFPD EDKPSNNNNN SNNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [175-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDDHSNHDVL HEDPSTNNRQ RNPHFLTQRR NTFLTSQYDQ SKSRFSSKNK RNGNNGETNN  60
   61 FGDNMQNNHP FEPNFMGSPS QFPADATNMT SIDHGGFTNV DITSTENNTT GDNGVDALSN 120
  121 LLHRTTHTPN RSSPLSNVTS AQNSSSQQRK HSESKVDSNS DNNSSNKAPN ITVPDYSIIP 180
  181 TSVLVTLLPR VNVPNGAYNS LISAGFDNDQ IDAIAAIMAY HHQKKIRENN SNNNKNINTN 240
  241 DSQEAPILKN INELLSVLIP PSPAETRGPT TLSTSPSFNE HGVVAEASFL SSILELGIKH 300
  301 PKSNNIHNQR QPSRNDHKIS RESDGNNGND NVHHNNAVIK SSTTRGDEIA KIRSEPTLNA 360
  361 SSSDHKENSL KRSHSGD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.42
Match: 1k83A
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [552-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNKKVPVDR KYSDNEDDEY DDADLHGFEK KQLIKKELGD DDEDLLIQSK KSHQKKKLKE  60
   61 KELESSIHEL TEIAASLQKR IHTLETENKL LKNLVLSSGE TEGIKKAESL KKQIFEKVQK 120
  121 E

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.01
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle