YRC Public Data Repository - Protein Structure Prediction

Protein:	AVT4
Organism:	Saccharomyces cerevisiae
Length:	713 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AVT4.

Description	E-value	Query Range	Subject Range
AVT4_YEAST - Vacuolar amino acid transporter 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AVT4 P... gi\|207341724 - gi\|207341724\|gb\|EDZ69701.1\| YNL101Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190409090 - gi\|190409090\|gb\|EDV12355.1\| gln [Saccharomyces cerevisiae RM11-1a] AVT4 - Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seve...	0.0	[1..713]	[1..713]
gi\|11347452 - pir\|\|B83270 aromatic amino acid transport protein AroP1 PA3000 [imported] - Pseudomonas aeruginosa (... gi\|15598196, gi\|... - gi\|9949101\|gb\|AAG06388.1\|AE004725_1 aromatic amino acid transport protein AroP1 [Pseudomonas aerugin...	3.0E-85	[289..713]	[7..442]
gi\|165936285, gi... - gi\|89104688\|ref\|ZP_01177224.1\| COG0833: Amino acid transporters [Yersinia pestis biovar Orientalis s... gi\|108807022, gi... - gi\|108807022\|ref\|YP_650938.1\| lysine transporter [Yersinia pestis Antiqua], gi\|108778935\|gb\|ABG12993... gi\|229679023, gi... - gi\|229903253\|ref\|ZP_04518366.1\| lysine transporter [Yersinia pestis Nepal516], gi\|229679023\|gb\|EEO75... Q66CR2\|Q66CR2_YERPS - Lysine-specific permease lysP, APC family precursor - Yersinia pseudotuberculosis gi\|166009838, gi... - gi\|166009838\|ref\|ZP_02230736.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. E... gi\|165924474, gi... - gi\|165924474\|ref\|ZP_02220306.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|167400403, gi... - gi\|167400403\|ref\|ZP_02305916.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. U... gi\|166211768, gi... - gi\|166211768\|ref\|ZP_02237803.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. B... gi\|167424094, gi... - gi\|167424094\|ref\|ZP_02315847.1\| lysine-specific permease LysP [Yersinia pestis biovar Mediaevalis st... gi\|167419868, gi... - gi\|167419868\|ref\|ZP_02311621.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|186894753, gi... - gi\|186894753\|ref\|YP_001871865.1\| lysine transporter [Yersinia pseudotuberculosis PB1/+], gi\|18669777... gi\|170024977, gi... - gi\|170024977\|ref\|YP_001721482.1\| lysine transporter [Yersinia pseudotuberculosis YPIII], gi\|16975151... gi\|229841266, gi... - gi\|229841266\|ref\|ZP_04461425.1\| lysine transporter [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229843369, gi... - gi\|229843369\|ref\|ZP_04463515.1\| lysine transporter [Yersinia pestis biovar Orientalis str. India 195... gi\|229895742, gi... - gi\|229895742\|ref\|ZP_04510912.1\| lysine transporter [Yersinia pestis Pestoides A], gi\|229700665\|gb\|EE... gi\|149366712, gi... - gi\|149366712\|ref\|ZP_01888746.1\| putative lysine-specific permease [Yersinia pestis CA88-4125], gi\|14... gi\|145599660, gi... - gi\|145599660\|ref\|YP_001163736.1\| lysine transporter [Yersinia pestis Pestoides F], gi\|145211356\|gb\|A... gi\|25296480 - pir\|\|AH0159 probable lysine-specific permease lysP [imported] - Yersinia pestis (strain CO92) gi\|45435969, gi\|... - gi\|45441110\|ref\|NP_992649.1\| lysine transporter [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22126753, gi\|... - gi\|22126753\|ref\|NP_670176.1\| lysine transporter [Yersinia pestis KIM], gi\|21959776\|gb\|AAM86427.1\|AE0... gi\|218928459, gi... - gi\|218928459\|ref\|YP_002346334.1\| lysine transporter [Yersinia pestis CO92], gi\|16121591\|ref\|NP_40490... gi\|51595681, gi\|... - gi\|51595681\|ref\|YP_069872.1\| lysine transporter [Yersinia pseudotuberculosis IP 32953], gi\|51588963\|... gi\|162353225, gi... - gi\|77634357\|ref\|ZP_00796459.1\| COG0833: Amino acid transporters [Yersinia pestis Angola], gi\|1624204... gi\|153948146, gi... - gi\|77632298\|ref\|ZP_00794884.1\| COG0833: Amino acid transporters [Yersinia pseudotuberculosis IP 3175...	2.0E-83	[281..710]	[5..444]
SPAC3H1.09c - vacuolar amino acid transporter AVT3_SCHPO - Vacuolar amino acid transporter 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=avt3 PE=...	4.0E-82	[88..711]	[74..656]
gi\|16799865 - gi\|16799865\|ref\|NP_470133.1\| hypothetical protein lin0791 [Listeria innocua Clip11262] gi\|16413242, gi\|... - pir\|\|AG1531 lysine-specific permease homolog lin0791 [imported] - Listeria innocua (strain Clip11262...	8.0E-82	[286..710]	[2..436]
lcl\|NC_016856.1_... - [gene=lysP] [protein=lysine transporter] [protein_id=YP_005238254.1] [location=complement(2350441..2... gi\|62128419, gi\|... - gi\|62180786\|ref\|YP_217203.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Cholera... gi\|16765530, gi\|... - gi\|16765530\|ref\|NP_461145.1\| lysine transporter [Salmonella typhimurium LT2], gi\|16420738\|gb\|AAL2110... gi\|56412888, gi\|... - gi\|56412888\|ref\|YP_149963.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Paratyp... gi\|207857634, gi... - gi\|207857634\|ref\|YP_002244285.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Ent... gi\|224583303, gi... - gi\|224583303\|ref\|YP_002637101.1\| lysine-specific permease [Salmonella enterica subsp. enterica serov... gi\|198245922, gi... - gi\|198245922\|ref\|YP_002216282.1\| lysine-specific permease [Salmonella enterica subsp. enterica serov... gi\|199604839, gi... - gi\|200387741\|ref\|ZP_03214353.1\| lysine-specific permease [Salmonella enterica subsp. enterica serova... gi\|197249090, gi... - gi\|197249090\|ref\|YP_002147171.1\| lysine-specific permease [Salmonella enterica subsp. enterica serov... gi\|197361819, gi... - gi\|197361819\|ref\|YP_002141455.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Par... gi\|194445176, gi... - gi\|194445176\|ref\|YP_002041472.1\| lysine-specific permease [Salmonella enterica subsp. enterica serov... gi\|194407284, gi... - gi\|194448980\|ref\|YP_002046253.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Hei... gi\|205350678, gi... - gi\|205350678\|gb\|EDZ37309.1\| lysine-specific permease [Salmonella enterica subsp. enterica serovar Ha... gi\|168466112, gi... - gi\|195631514\|gb\|EDX50074.1\| lysine-specific permease [Salmonella enterica subsp. enterica serovar Ne... gi\|205330473, gi... - gi\|205330473\|gb\|EDZ17237.1\| lysine-specific permease [Salmonella enterica subsp. enterica serovar 4,... gi\|168242294, gi... - gi\|205338283\|gb\|EDZ25047.1\| lysine-specific permease [Salmonella enterica subsp. enterica serovar He... gi\|161362466, gi... - gi\|161613102\|ref\|YP_001587067.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Par... gi\|205324087, gi... - gi\|205324087\|gb\|EDZ11926.1\| lysine-specific permease [Salmonella enterica subsp. enterica serovar Sa...	1.0E-81	[286..710]	[6..440]
gi\|1778491 - gi\|1778491\|gb\|AAB40774.1\| phenylalanine-specific permease [Escherichia coli]	1.0E-81	[264..705]	[2..440]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-81	[286..710]	[6..440]
gi\|16761141 - gi\|16761141\|ref\|NP_456758.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Typhi s... gi\|16503439, gi\|... - gi\|25296491\|pir\|\|AH0782 lysine-specific permease [imported] - Salmonella enterica subsp. enterica se... gi\|29136791, gi\|... - gi\|29141165\|ref\|NP_804507.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Typhi s... gi\|213648839 - gi\|213648839\|ref\|ZP_03378892.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Typh... gi\|213424243 - gi\|213424243\|ref\|ZP_03357102.1\| lysine transporter [Salmonella enterica subsp. enterica serovar Typh...	2.0E-81	[286..710]	[6..440]

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Predicted Domain #1

Region A:
Residues: [1-234]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTNNGDGEH LGIRRNGNLR HPSNNMKIPR RAQSTVLNSN PFYSRKYSMS TLTPRDICRS  60
   61 VDSRVFVDMS SPNFQTLEDP HRDEIINSVR LNYLNSSKRS SVSHGNEAIP RVNPTKNSSA 120
  121 STIAAANVDS DDDETNLSSA GGDITHDIYK LVKAEDPKRL RRPRSMENVT PKIEHHTKLS 180
  181 SASGLNVPGG FRREFIVNKK RQEHQLNDSA SSDFTSHESD SINQSSPSSN QDID

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [235-713]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVPFLTRNFL EFLYVFGHFA GESFEDDFIP DSSNMMIRGE DERSALLSRP DHMKVLPSAK  60
   61 GTTSTKKVFL ILLKSFIGTG VLFLPNAFHN GGLFFSVSML AFFGIYSYWC YYILVQAKSS 120
  121 CGVSSFGDIG LKLYGPWMRI IILFSLVITQ VGFSGAYMIF TAKNLQAFLD NVFHVGVLPL 180
  181 SYLMVFQTII FIPLSFIRNI SKLSLPSLLA NFFIMAGLVI VIIFTAKRLF FDLMGTPAMG 240
  241 VVYGLNADRW TLFIGTAIFA FEGIGLIIPV QDSMRNPEKF PLVLALVILT ATILFISIAT 300
  301 LGYLAYGSNV QTVILLNLPQ SNIFVNLIQL FYSIAIMLST PLQLFPAIKI IENKFFPKFT 360
  361 KIYVKHDDLT TRVELRPNSG KLNWKIKWLK NFIRSIIVII VVSIAYFGSD NLDKFVSVIG 420
  421 SLACIPLVYI YPSMLHLRGN SLPETKGEFW RFKPMLDTIL IFFGIASMLY TSYQSIFGV

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	152.638272
Match:	PF01490
Description:	Transmembrane amino acid transporter protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits