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View Structure Prediction Details

Protein: TCB2
Organism: Saccharomyces cerevisiae
Length: 1178 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TCB2.

Description E-value Query
Range
Subject
Range
gi|71064113 - gi|71064113|gb|AAZ22521.1| Tcb2p [Saccharomyces cerevisiae]
848.0 [0..1] [1178..1]
gi|49641952 - gi|49641952|emb|CAH01670.1| KLLA0C13860p [Kluyveromyces lactis]
gi|49641952, gi|... - gi|50305717|ref|XP_452819.1| unnamed protein product [Kluyveromyces lactis], gi|49641952|emb|CAH0167...
706.0 [0..12] [1138..16]
gi|6687541 - gi|6687541|emb|CAB65007.1| transmembrane protein [Erysiphe pisi]
704.0 [0..42] [1165..105]
gi|50291297, gi|... - gi|50291297|ref|XP_448081.1| unnamed protein product [Candida glabrata], gi|49527392|emb|CAG61032.1|...
gi|49527392 - gi|49527392|emb|CAG61032.1| unnamed protein product [Candida glabrata]
662.0 [0..5] [1139..42]
gi|44984080 - gi|44984080|gb|AAS53090.1| AER411Wp [Ashbya gossypii ATCC 10895]
gi|44984080, gi|... - gi|45191012|ref|NP_985266.1| AER411Wp [Ashbya gossypii ATCC 10895], gi|44984080|gb|AAS53090.1| AER41...
642.0 [0..1] [1138..11]
YKH3_SCHPO - Uncharacterized protein PYUK71.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAPYUK...
SPAPYUK71.03c - C2 domain protein
639.0 [0..11] [1173..74]
gi|38099370, gi|... - gi|39965448|ref|XP_365102.1| hypothetical protein MG09947.4 [Magnaporthe grisea 70-15], gb|EAA46726....
622.0 [0..59] [1115..130]
gi|169781998 - gi|169781998|ref|XP_001825462.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83774204 - gi|83774204|dbj|BAE64329.1| unnamed protein product [Aspergillus oryzae]
610.0 [0..84] [1110..158]
gi|115385264, gi... - gi|115385264|ref|XP_001209179.1| hypothetical protein ATEG_01814 [Aspergillus terreus NIH2624], gi|1...
609.0 [0..3] [1110..73]

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Predicted Domain #1
Region A:
Residues: [1-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPNSSKTRT DQISSMPGIN EATKVESKNV VKDAVPIKSE VETNGTSIVR EKQDPSYVGW  60
   61 KQVGGWEEKD ELTSEDLLVD VNKDTFLGNL LPDKFYGDWY HEVAILIIAG LCSFVLGYFK 120
  121 FSLASVLIVM LTTGMLYRTS SKKYRESLRD LAQKEQTVEK ITSDYESVEW LNTFLDKYWP 180
  181 IIEPSVSQQI VDGTNTALSE NVAIPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [207-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIKAIWLDQF TLGVKPPRID AIKTFQNTKS DVVVMDVCLS FTPHDMSDLD AKQCRNYVNS  60
   61 NVVLKAKIFG MDIPVSVADI FFQVFVRFRF QLMTTLPLVE TINIQLLEVP EVDFISRLLG 120
  121 NSVFNWEILA IPGLMRLIQK MAFKYLSPVL LPPFSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.124002
Match: 1dqvA
Description: Synaptogamin I
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [363-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLNIPQLLSK TGLPIGVLEI KVKNAHGLRK LVGMIKKTVD PYLTFELSGK IVGKTKVFKN  60
   61 SANPVWNESI YILLQSFTDP LTIAVYDKRE TLSDKKMGTV IFNLNKLHAN HYHKNEKVHF 120
  121 LRNSKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.124002
Match: 1dqvA
Description: Synaptogamin I
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [489-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGELTFDLRF FPTIEPKKLL NGDEEPLPDM NTGITKITIR ELKGLDELSD KKFVFAELYV  60
   61 NAELVMTTKK EKRTAHLKWN SDYYSVVTDR RKTICRFVLK DQSGKVISSS VQPLNHLIDR 120
  121 TEVNKEWIPL RNGK

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.78
Match:
Description: No description for 1bynA was found.

Predicted Domain #5
Region A:
Residues: [623-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GELKVTTYWR PVDIDLGLKS VGYTTPIGML RVFINKAENL RNPDSLGKIS PYAKVSVNGV  60
   61 ARGRTNERIE TLNPIWNQSI YVSVTSPLQK VSIDCFGIDT NGDDHNLGSL NIQTQNIYHK 120
  121 DNDDKYTIFI DNAPRTGNLI GKKGVKGTVT YYLSFYPVV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.751666
Match: 1k5wA
Description: Synaptogamin I
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [782-922]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVLSLEEAKE VDEINEKKDK LEKQKSTLDD KNISKEEKER IKKEEFRLTE KYDMYSYKMK  60
   61 LDLDELLQYN AGVLGVTVLG GELPQPGLYV QTFFDSCGYA AITSAKNAIR TIKTGWSGDF 120
  121 MIKELEWSVT TFRVTKTKDA N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [923-1119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAENFICEVN IPTIELVRNC YYKPSVLNLI GKKSAKLLVQ VSWFPVTATE LPQSDLITNS  60
   61 GDLKITAKSA ENLIGVNKNG YSDPYVEFFL NEKSTSPFFK TAVQKKTLNP TWNESKTIEV 120
  121 SNRVNDYLTI NVKDYESTNS NRSIGKAVVP LSTIDPESDT TFNIPLVGPK GEDGGVLHLE 180
  181 FEFEPRYTTN VVKREAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.9794
Match: 1rsyA
Description: STRUCTURE OF THE FIRST C2-DOMAIN OF SYNAPTOTAGMIN I: A NOVEL CA2+(SLASH)PHOSPHOLIPID BINDING FOLD
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1120-1178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGNFATKGLG TGIKAGSTVF ALGTNVVSTG LGTIDKVKAG VFGGKKSTTT GDKKSEEKQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle