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View Structure Prediction Details

Protein: ALG11
Organism: Saccharomyces cerevisiae
Length: 548 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALG11.

Description E-value Query
Range
Subject
Range
ALG11_YEAST - GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Saccharomyces cerevisiae (strain ATC...
ALG11 - Alpha-1,2-mannosyltransferase, catalyzes sequential addition of the two terminal alpha 1,2-mannose r...
4.0E-94 [1..548] [1..548]
SUS1_ORYSJ - Sucrose synthase 1 OS=Oryza sativa subsp. japonica GN=SUS1 PE=1 SV=1
SUS2_ORYSA - Sucrose synthase 2 (EC 2.4.1.13) (Sucrose-UDP glucosyltransferase 2) - Oryza sativa (Rice)
4.0E-88 [77..539] [298..808]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-88 [77..539] [298..808]
SUS2_PEA - Sucrose synthase 2 OS=Pisum sativum GN=SUS2 PE=2 SV=1
3.0E-87 [81..540] [300..808]
SUS2_TULGE - Sucrose synthase 2 OS=Tulipa gesneriana PE=2 SV=1
3.0E-87 [77..539] [294..804]
gi|3758873 - gi|3758873|emb|CAA09593.1| sucrose synthase [Solanum lycopersicum]
4.0E-87 [77..539] [293..803]
gi|6682841 - gi|6682841|dbj|BAA88904.1| sucrose synthase [Citrus unshiu]
6.0E-87 [81..546] [299..811]
SUSY1_ARATH - Sucrose synthase 1 OS=Arabidopsis thaliana GN=SUS1 PE=1 SV=3
6.0E-87 [77..540] [295..806]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSAWTNYNF EEVKSHFGFK KYVVSSLVLV YGLIKVLTWI FRQWVYSSLN PFSKKSSLLN  60
   61 RAVASCGEK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.464 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.567 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.551 a.5.6 Hypothetical protein MTH1615
View Download 0.467 a.60.13 Putative methyltransferase TM0872, insert domain
View Download 0.496 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.463 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.441 a.17.1 p8-MTCP1
View Download 0.434 a.144.2 Ribosomal protein L20
View Download 0.424 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.406 a.64.2 Bacteriocin AS-48
View Download 0.402 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.395 a.29.2 Bromodomain
View Download 0.395 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.392 a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.385 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.385 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.373 a.4.1 Homeodomain-like
View Download 0.350 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.340 a.24.17 Group V grass pollen allergen
View Download 0.337 a.144.1 PABC (PABP) domain
View Download 0.334 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.326 a.60.11 Hypothetical protein YjbJ
View Download 0.321 a.5.2 UBA-like
View Download 0.321 a.140.2 SAP domain
View Download 0.320 a.5.6 Hypothetical protein MTH1615
View Download 0.313 a.112.1 Description not found.
View Download 0.309 a.4.1 Homeodomain-like
View Download 0.303 a.4.1 Homeodomain-like
View Download 0.301 a.60.2 RuvA domain 2-like
View Download 0.300 a.60.1 SAM/Pointed domain
View Download 0.293 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.291 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.291 a.7.6 Ribosomal protein S20
View Download 0.286 a.77.1 DEATH domain
View Download 0.286 a.144.1 PABC (PABP) domain
View Download 0.285 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.285 a.3.1 Cytochrome c
View Download 0.283 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.278 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.275 a.3.1 Cytochrome c
View Download 0.272 a.4.1 Homeodomain-like
View Download 0.270 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.269 a.60.12 DNA polymerase beta-like, second domain
View Download 0.267 a.61.1 Retroviral matrix proteins
View Download 0.266 a.28.1 ACP-like
View Download 0.263 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.262 a.144.2 Ribosomal protein L20
View Download 0.260 a.3.1 Cytochrome c
View Download 0.248 a.64.2 Bacteriocin AS-48
View Download 0.243 f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.241 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.240 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.239 a.6.1 Putative DNA-binding domain
View Download 0.238 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.237 a.28.1 ACP-like
View Download 0.230 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.229 d.120.1 Cytochrome b5
View Download 0.228 a.64.1 Saposin
View Download 0.228 a.28.1 ACP-like
View Download 0.225 a.4.1 Homeodomain-like
View Download 0.225 a.2.3 Chaperone J-domain
View Download 0.218 d.120.1 Cytochrome b5
View Download 0.217 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.217 f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.215 a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.214 a.3.1 Cytochrome c
View Download 0.214 a.74.1 Cyclin-like
View Download 0.213 a.118.8 TPR-like
View Download 0.211 a.180.1 N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
View Download 0.210 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.210 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.208 a.140.1 LEM domain
View Download 0.206 a.77.1 DEATH domain
View Download 0.203 d.74.2 C-terminal domain of arginine repressor
View Download 0.202 a.39.1 EF-hand

Predicted Domain #2
Region A:
Residues: [70-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVKVFGFFHP YCNAGGGGEK VLWKAVDITL RKDAKNVIVI YSGDFVNGEN VTPENILNNV  60
   61 KAKFDYDLDS DRIFFISLKL RYLVDSSTWK HFTLIGQAIG SMILAFESII QCPPDIWIDT 120
  121 MGYPFSYPII ARFLRRIPIV T

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [484-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPLRYPNLSD LFLQITKLDY DCLRVMGARN QQYSLYKFSD LKFDKDWENF VLNPICKLLE  60
   61 EEERG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.31
Match: 1iirA
Description: UDP-glucosyltransferase GtfB
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [211-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTHYPIMSKD MLNKLFKMPK KGIKVYGKIL YWKVFMLIYQ SIGSKIDIVI TNSTWTNNHI  60
   61 KQIWQSNTCK IIYPPCST

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [479-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNTTK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.31
Match: 1iirA
Description: UDP-glucosyltransferase GtfB
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [289-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKLVDWKQKF GTAKGERLNQ AIVLAQFRPE KRHKLIIESF ATFLKNLPDS VSPIKLIMAG  60
   61 STRSKQDENY VKSLQDWSEN VLKIPKHLIS FEKNLPFDKI EILLNKSTFG VNAMWNEHFG 120
  121 IAVVEYMASG LIPIVHASAG PLLDIVTPWD ANGNIGKAPP QWELQKKYFA KLEDDGETTG 180
  181 FFFKEPSDPD 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.31
Match: 1iirA
Description: UDP-glucosyltransferase GtfB
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle