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View Structure Prediction Details

Protein: IDH1
Organism: Saccharomyces cerevisiae
Length: 360 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IDH1.

Description E-value Query
Range
Subject
Range
gi|125569901, gi... - gi|81686717|dbj|BAE48299.1| NAD-dependent isocitrate dehydrogenase a [Oryza sativa Japonica Group], ...
0.0 [1..357] [6..362]
gi|3790188 - gi|3790188|emb|CAA74776.1| NAD-dependent isocitrate dehydrogenase [Nicotiana tabacum]
0.0 [3..358] [15..371]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..357] [5..372]
IDH5_ARATH - Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial OS=Arabidopsis thaliana GN=IDH5 PE...
0.0 [1..357] [7..374]
gi|194204815, gi... - gi|195567723|ref|XP_002107408.1| GD15579 [Drosophila simulans], gi|194204815|gb|EDX18391.1| GD15579 ...
FBpp0307649 - type=protein; loc=X:complement(19413320..19413658,19413729..19413864,19413937..19414331,19414693..19...
0.0 [2..357] [17..377]

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Predicted Domain #1
Region A:
Residues: [1-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNRTIAKRT LATAAQAERT LPKKYGGRFT VTLIPGDGVG KEITDSVRTI FEAENIPIDW  60
   61 ETINIKQTDH KEGVYEAVES LKRNKIGLKG LWHTPADQTG HGSLNVALRK QLDIYANVAL 120
  121 FKSLKGVKTR IPDIDLIVIR ENTEGEFSGL EHESVPGVVE SLKVMTRPKT ERIARFAFDF 180
  181 AKKYNRKSVT AVHKANIMKL GDGLFRNIIT EIGQKEYPDI DVSSIIVDNA SMQAVAKPHQ 240
  241 FDVLVTPSMY GTILGNIGAA LIGGPGLVAG ANFGRDYAVF EPGSRHVGLD IKGQNVANPT 300
  301 AMILSSTLML NHLGLNEYAT RISKAVHETI AEGKHTTRDI GGSSSTTDFT NEIINKLSTM 360
  361 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 511.218487
Match: 1xac__
Description: 3-isopropylmalate dehydrogenase, IPMDH
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle