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View Structure Prediction Details

Protein: ARK1
Organism: Saccharomyces cerevisiae
Length: 638 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARK1.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..485] [73..537]
gi|5162880, gi|5... - gi|5162880|dbj|BAA81750.1| calcium-dependent protein kinase [Marchantia polymorpha], gi|5162877|dbj|...
0.0 [3..506] [62..547]
gi|19171502 - gi|19171502|emb|CAC87494.1| calcium-dependent protein kinase [Solanum lycopersicum]
0.0 [1..485] [85..549]
CDPK_DAUCA - Calcium-dependent protein kinase OS=Daucus carota PE=2 SV=2
0.0 [3..474] [62..513]
gi|13561063 - gi|13561063|emb|CAA65500.1| protein kinase [Medicago sativa]
0.0 [4..484] [70..538]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQPQIGTYN VGTQLTVGSH QVEIIKYLTS GGFAQVYSAL INPPDPHSNS SVACLKRVIV  60
   61 PDKPSLNTLR 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [89-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDSHAAKAML HNGSYEVFVL ME

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 221.741366
Match: 2phkA_
Description: gamma-subunit of glycogen phosphorylase kinase (Phk)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [71-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEVDAMRLLK NNRYVVSY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [111-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YCERGGLIDF MNTRLQNRLH EFEILQIMSQ VTQGVAAMHA LQPPLIHRDI KIENVLISAN  60
   61 NEYKLCDFGS VCGIIRPPRN SQELSYVQQD ILKNTTAQYR SPEMIDTFRG LPIDEKSDIW 120
  121 ALGIFLYKLC YYTTPFEKGG DLAILSGKFE FPLYPNYSEQ LKGLIRDILV QDPRHRPNVY 180
  181 QLLKRISIMQ NVPCPINDIQ VVQAPSSHLN LTELHQLSAT QNILS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 221.741366
Match: 2phkA_
Description: gamma-subunit of glycogen phosphorylase kinase (Phk)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [336-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNSPTTMENT MPNATFQISM ADNTTTAQMH PNRKPSQIAY DASFSNSAKG SQPLFDKSQN  60
   61 MYHALDPPLV EPLASSVSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1cdlA_
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [415-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDNELKANSA TKLKQAIVSE AHTFRQNNSI DFPLQNIIPQ YEDSSSSSDE SYSGDVDELK  60
   61 KTRSLGSYST RGNIKKNQSV KESLTSSSLP GTSFTPTSTK VNLKHEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1cdlA_
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [522-638]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPFKSTFVNT IDNSKDDLNK PSYEDLDVSK QNLKNSIQQR MIDKLNSSEE SFNARKMSKV  60
   61 KLHEKGEIDK PTMLKSSGPI SKDKKTKPTP PPKPSHLKPK PPPKPLLLAG RKLSLDK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.413 a.1.1 Globin-like
View Download 0.408 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.401 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.442 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.425 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.376 a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.357 a.24.15 FAD-dependent thiol oxidase
View Download 0.340 a.4.5 "Winged helix" DNA-binding domain
View Download 0.339 f.14.1 Voltage-gated potassium channels
View Download 0.327 a.1.1 Globin-like
View Download 0.322 a.4.3 ARID-like
View Download 0.320 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.304 a.118.1 ARM repeat
View Download 0.278 d.58.7 RNA-binding domain, RBD
View Download 0.275 a.1.1 Globin-like
View Download 0.252 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.251 a.26.1 4-helical cytokines
View Download 0.247 d.169.1 C-type lectin-like
View Download 0.247 a.142.1 PTS-regulatory domain, PRD
View Download 0.242 a.92.1 Carbamoyl phosphate synthetase, large subunit connection domain
View Download 0.240 c.20.1 Initiation factor IF2/eIF5b, domain 3
View Download 0.240 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.234 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.229 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.226 a.74.1 Cyclin-like
View Download 0.215 g.53.1 TAZ domain
View Download 0.212 a.1.1 Globin-like
View Download 0.208 c.56.1 HybD-like
View Download 0.205 a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle