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View Structure Prediction Details

Protein: DML1
Organism: Saccharomyces cerevisiae
Length: 475 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DML1.

Description E-value Query
Range
Subject
Range
TBB1_MAIZE - Tubulin beta-1 chain OS=Zea mays GN=TUBB1 PE=2 SV=1
0.0 [80..470] [8..430]
TBB_PARLI - Tubulin beta chain OS=Paracentrotus lividus PE=2 SV=1
0.0 [80..470] [8..430]
TBB4_XENLA - Tubulin beta-4 chain OS=Xenopus laevis GN=tubb4 PE=2 SV=1
0.0 [80..470] [8..430]
TBB1_MANSE - Tubulin beta-1 chain OS=Manduca sexta PE=2 SV=1
0.0 [80..473] [8..433]
gi|2443346 - gi|2443346|dbj|BAA22382.1| beta-tubulin [Halocynthia roretzi]
0.0 [80..470] [8..430]
gi|19773428, gi|... - gi|19773428|dbj|BAB86853.1| beta-tubulin [Bombyx mori], gi|112983318|ref|NP_001036964.1| beta-tubuli...
0.0 [80..473] [8..433]
gi|10242186 - gi|10242186|gb|AAG15328.1|AF255954_1 beta tubulin [Chionodraco rastrospinosus]
gi|10242160 - gi|10242160|gb|AAG15315.1|AF255553_1 beta tubulin [Notothenia coriiceps]
0.0 [80..470] [8..430]
TBB2_ECHMU - Tubulin beta-2 chain OS=Echinococcus multilocularis GN=TUB-2 PE=3 SV=1
0.0 [80..470] [8..430]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHEVVTISVS QRANHLTTQF FNIQEGYLQL SKEQQVNDSK IFLNSVVDKV SKTISYAPRA  60
   61 LLWDARTGNG SLGTYQYSE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.555 0.247 mitochondrial genome maintenance b.71.1 Glycosyl hydrolase domain
View Download 0.562 0.103 mitochondrial genome maintenance d.15.7 Immunoglobulin-binding domains
View Download 0.633 0.061 mitochondrial genome maintenance a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.590 0.011 mitochondrial genome maintenance a.24.17 Group V grass pollen allergen
View Download 0.593 N/A N/A a.112.1 Description not found.
View Download 0.553 N/A N/A d.9.1 Interleukin 8-like chemokines
View Download 0.538 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.535 N/A N/A a.17.1 p8-MTCP1
View Download 0.524 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.504 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.498 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.483 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.471 N/A N/A d.15.1 Ubiquitin-like
View Download 0.468 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.467 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.457 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.451 N/A N/A c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.440 N/A N/A b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.438 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.428 N/A N/A a.4.1 Homeodomain-like
View Download 0.422 N/A N/A b.36.1 PDZ domain-like
View Download 0.418 N/A N/A a.77.1 DEATH domain
View Download 0.417 N/A N/A a.46.1 Methionine synthase domain
View Download 0.412 N/A N/A b.1.2 Fibronectin type III
View Download 0.410 N/A N/A c.47.1 Thioredoxin-like
View Download 0.409 N/A N/A c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.408 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.407 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.406 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.403 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.394 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.388 N/A N/A a.64.1 Saposin
View Download 0.385 N/A N/A b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.384 N/A N/A a.112.1 Description not found.
View Download 0.380 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.379 N/A N/A a.2.3 Chaperone J-domain
View Download 0.376 N/A N/A b.1.1 Immunoglobulin
View Download 0.375 N/A N/A a.64.1 Saposin
View Download 0.370 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.369 N/A N/A b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.367 N/A N/A a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.363 N/A N/A b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.362 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.360 N/A N/A c.55.4 Translational machinery components
View Download 0.359 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.349 N/A N/A a.74.1 Cyclin-like
View Download 0.348 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.346 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.345 N/A N/A a.105.1 FIS-like
View Download 0.345 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.345 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.345 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.344 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.343 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.341 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.340 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.337 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.334 N/A N/A d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.332 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.331 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.330 N/A N/A b.36.1 PDZ domain-like
View Download 0.329 N/A N/A d.47.1 Ribosomal protein L11, N-terminal domain
View Download 0.328 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.327 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.325 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.324 N/A N/A a.29.2 Bromodomain
View Download 0.324 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.322 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.322 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.319 N/A N/A b.36.1 PDZ domain-like
View Download 0.307 N/A N/A b.36.1 PDZ domain-like
View Download 0.303 N/A N/A b.1.18 E set domains
View Download 0.301 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.299 N/A N/A c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.298 N/A N/A i.1.1 Ribosome and ribosomal fragments
View Download 0.297 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.297 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.290 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.288 N/A N/A d.95.2 Homing endonucleases
View Download 0.282 N/A N/A a.47.2 t-snare proteins
View Download 0.282 N/A N/A d.58.49 YajQ-like
View Download 0.281 N/A N/A a.21.1 HMG-box
View Download 0.275 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.267 N/A N/A d.58.49 YajQ-like
View Download 0.264 N/A N/A b.1.14 Invasin/intimin cell-adhesion fragments
View Download 0.256 N/A N/A a.5.6 Hypothetical protein MTH1615
View Download 0.253 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.252 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.251 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.248 N/A N/A d.13.1 HIT-like
View Download 0.237 N/A N/A d.10.1 DNA-binding domain
View Download 0.237 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.237 N/A N/A b.3.5 B repeat unit of collagen binding surface protein (cna)
View Download 0.233 N/A N/A a.2.2 Ribosomal protein L29 (L29p)
View Download 0.231 N/A N/A c.55.4 Translational machinery components
View Download 0.230 N/A N/A d.88.1 SRF-like
View Download 0.228 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.227 N/A N/A b.1.14 Invasin/intimin cell-adhesion fragments
View Download 0.227 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.226 N/A N/A b.7.3 PHL pollen allergen
View Download 0.225 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.224 N/A N/A d.15.6 Superantigen toxins, C-terminal domain
View Download 0.218 N/A N/A c.49.1 Pyruvate kinase, C-terminal domain
View Download 0.216 N/A N/A a.2.7 tRNA-binding arm
View Download 0.216 N/A N/A a.2.7 tRNA-binding arm
View Download 0.213 N/A N/A a.74.1 Cyclin-like
View Download 0.210 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.202 N/A N/A b.1.1 Immunoglobulin
View Download 0.202 N/A N/A b.1.1 Immunoglobulin

Predicted Domain #2
Region A:
Residues: [80-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQDYHFGNED KFKEQTVIKT HPRIPKSEYQ SSLDAGAPLP CLNRENTMYW SDYSKLIYGP  60
   61 SSFNILRNWY HDTENPNQPD FQNLGERKFD RYSIGYDEFT ENYLQEFFDG NLHRELEKCD 120
  121 TLQGFNLVSD MESGWGGFSS ALLVELRNEL PKKAVFSWGH NEDDPFTDDF PMKRLSKKWL 180
  181 PIISNKLRST INMMQESDLY FPLYAAPGLT NWETAGKSCR IFDSINATIS QSNLEQRKTM 240
  241 DYLTTAITLG YSSRNMVTGM VIGDTDYSFC SRVLPFKNSH KPNSTHIFSK SFIDRGNQTH 300
  301 KHHSEPDSRS KMIEMYTHRY FPSDTIPTEF SNDREFVLEL ESSEKNRDIF KHWNEFVVRY 360
  361 FKNDSDREEL KNELSDYASA YESGWYEDED SGDDDM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 153.0
Match: 1ffxB_
Description: Tubulin:stathmin-like domain complex
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle