YRC Public Data Repository - Protein Structure Prediction

Protein:	TOM40
Organism:	Saccharomyces cerevisiae
Length:	387 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOM40.

Description	E-value	Query Range	Subject Range
gi\|207342175 - gi\|207342175\|gb\|EDZ70021.1\| YMR203Wp-like protein [Saccharomyces cerevisiae AWRI1631] TOM40_YEAST - Mitochondrial import receptor subunit TOM40 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)... TOM40 - Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial... gi\|190408429 - gi\|190408429\|gb\|EDV11694.1\| mitochondrial import receptor subunit TOM40 [Saccharomyces cerevisiae RM...	0.0	[1..387]	[1..387]
tom40 - mitochondrial TOM complex subunit Tom40 TOM40_SCHPO - Probable mitochondrial import receptor subunit tom40 OS=Schizosaccharomyces pombe (strain 972 / ATCC...	6.0E-88	[37..368]	[7..332]
gi\|19112338 - gi\|19112338\|ref\|NP_595546.1\| mitochondrial outer membrane translocase [Schizosaccharomyces pombe 972... gi\|2853119, gi\|7... - gi\|7522289\|pir\|\|T40037 probable mitochondrial import receptor subunit - fission yeast (Schizosacchar...	7.0E-78	[37..345]	[7..309]
TOM40_NEUCR, OM4... - Mitochondrial import receptor subunit tom-40 OS=Neurospora crassa GN=tom-40 PE=1 SV=1, (P24391) Mito... TOM40_NEUCR - Mitochondrial import receptor subunit tom40 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / C...	4.0E-73	[35..373]	[16..341]
TO401_ARATH - Mitochondrial import receptor subunit TOM40-1 OS=Arabidopsis thaliana GN=TOM40-1 PE=1 SV=3	1.0E-70	[35..358]	[6..307]
VDAC1_RAT - Voltage-dependent anion-selective channel protein 1 OS=Rattus norvegicus GN=Vdac1 PE=1 SV=4 gi\|74141951, gi\|... - gi\|74219876\|dbj\|BAE40522.1\| unnamed protein product [Mus musculus], gi\|74143985\|dbj\|BAE41292.1\| unna...	3.0E-68	[57..360]	[1..300]
gi\|6650562 - gi\|6650562\|gb\|AAF21906.1\|AF109918_1 mitochondrial outer membrane protein MOM35 [Mus musculus]	8.0E-68	[58..359]	[38..320]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAPTPLAEA SQIPTIPALS PLTAKQSKGN FFSSNPISSF VVDTYKQLHS HRQSLELVNP  60
   61 GTVENLNKEV SRDVFLSQYF FTGLRADLNK AFSMNPAFQT SHTFSIGSQA LPKYAFSALF 120
  121 ANDNLFAQGN IDNDLSVSGR LNYGWDKKNI SKVNLQIS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [159-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGQPTMCQLE QDYQASDFSV NVKTLNPSFS EKGEFTGVAV ASFLQSVTPQ LALGLETLYS  60
   61 RTDGSAPGD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.886	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.707	0.237	mitochondrial outer membrane translocase complex	d.43.1	Elongation factor Ts (EF-Ts), dimerisation domain
View	Download	0.662	0.237	mitochondrial outer membrane translocase complex	a.60.4	DNA repair protein Rad51, N-terminal domain
View	Download	0.886	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.841	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.832	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.823	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.821	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.658	0.237	mitochondrial outer membrane translocase complex	d.15.7	Immunoglobulin-binding domains
View	Download	0.635	0.237	mitochondrial outer membrane translocase complex	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.623	0.237	mitochondrial outer membrane translocase complex	d.15.6	Superantigen toxins, C-terminal domain
View	Download	0.620	0.237	mitochondrial outer membrane translocase complex	a.36.1	Signal peptide-binding domain
View	Download	0.610	0.237	mitochondrial outer membrane translocase complex	d.15.1	Ubiquitin-like
View	Download	0.603	0.237	mitochondrial outer membrane translocase complex	b.4.1	HSP40/DnaJ peptide-binding domain
View	Download	0.601	0.237	mitochondrial outer membrane translocase complex	a.4.1	Homeodomain-like
View	Download	0.592	0.237	mitochondrial outer membrane translocase complex	d.15.5	Staphylokinase/streptokinase
View	Download	0.583	0.237	mitochondrial outer membrane translocase complex	a.46.2	Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View	Download	0.551	0.237	mitochondrial outer membrane translocase complex	a.60.3	C-terminal domain of RNA polymerase alpha subunit
View	Download	0.538	0.237	mitochondrial outer membrane translocase complex	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.531	0.237	mitochondrial outer membrane translocase complex	d.214.1	Hypothetical protein MTH1880
View	Download	0.529	0.237	mitochondrial outer membrane translocase complex	d.58.20	NAD-binding domain of HMG-CoA reductase
View	Download	0.517	0.237	mitochondrial outer membrane translocase complex	d.15.1	Ubiquitin-like
View	Download	0.500	0.237	mitochondrial outer membrane translocase complex	c.55.4	Translational machinery components
View	Download	0.480	0.237	mitochondrial outer membrane translocase complex	a.4.1	Homeodomain-like
View	Download	0.480	0.237	mitochondrial outer membrane translocase complex	a.16.1	S15/NS1 RNA-binding domain
View	Download	0.455	0.237	mitochondrial outer membrane translocase complex	a.3.1	Cytochrome c
View	Download	0.452	0.237	mitochondrial outer membrane translocase complex	b.52.2	ADC-like
View	Download	0.440	0.237	mitochondrial outer membrane translocase complex	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.425	0.237	mitochondrial outer membrane translocase complex	a.48.3	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View	Download	0.420	0.237	mitochondrial outer membrane translocase complex	a.4.1	Homeodomain-like
View	Download	0.415	0.237	mitochondrial outer membrane translocase complex	a.61.1	Retroviral matrix proteins
View	Download	0.399	0.237	mitochondrial outer membrane translocase complex	d.58.44	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View	Download	0.390	0.237	mitochondrial outer membrane translocase complex	d.58.25	Killer toxin KP6 alpha-subunit
View	Download	0.378	0.237	mitochondrial outer membrane translocase complex	c.55.4	Translational machinery components
View	Download	0.362	0.237	mitochondrial outer membrane translocase complex	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.352	0.237	mitochondrial outer membrane translocase complex	d.54.1	Enolase N-terminal domain-like
View	Download	0.343	0.237	mitochondrial outer membrane translocase complex	d.15.1	Ubiquitin-like
View	Download	0.330	0.237	mitochondrial outer membrane translocase complex	d.192.1	YlxR-like
View	Download	0.328	0.237	mitochondrial outer membrane translocase complex	d.52.4	YhbC-like, N-terminal domain
View	Download	0.324	0.237	mitochondrial outer membrane translocase complex	a.74.1	Cyclin-like
View	Download	0.312	0.237	mitochondrial outer membrane translocase complex	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.310	0.237	mitochondrial outer membrane translocase complex	a.46.1	Methionine synthase domain
View	Download	0.305	0.237	mitochondrial outer membrane translocase complex	b.1.1	Immunoglobulin
View	Download	0.305	0.237	mitochondrial outer membrane translocase complex	d.15.5	Staphylokinase/streptokinase
View	Download	0.302	0.237	mitochondrial outer membrane translocase complex	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.302	0.237	mitochondrial outer membrane translocase complex	d.15.11	Doublecortin (DC)
View	Download	0.300	0.237	mitochondrial outer membrane translocase complex	b.43.4	Riboflavin synthase domain-like
View	Download	0.290	0.237	mitochondrial outer membrane translocase complex	d.58.12	eEF-1beta-like
View	Download	0.288	0.237	mitochondrial outer membrane translocase complex	a.4.6	C-terminal effector domain of the bipartite response regulators
View	Download	0.272	0.237	mitochondrial outer membrane translocase complex	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.271	0.237	mitochondrial outer membrane translocase complex	a.74.1	Cyclin-like
View	Download	0.268	0.237	mitochondrial outer membrane translocase complex	a.2.9	C-terminal UvrC-binding domain of UvrB
View	Download	0.263	0.237	mitochondrial outer membrane translocase complex	d.15.2	CAD & PB1 domains
View	Download	0.236	0.237	mitochondrial outer membrane translocase complex	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.229	0.237	mitochondrial outer membrane translocase complex	b.43.4	Riboflavin synthase domain-like
View	Download	0.223	0.237	mitochondrial outer membrane translocase complex	a.77.1	DEATH domain
View	Download	0.219	0.237	mitochondrial outer membrane translocase complex	d.68.1	Translation initiation factor IF3, C-terminal domain
View	Download	0.216	0.237	mitochondrial outer membrane translocase complex	a.8.1	Bacterial immunoglobulin/albumin-binding domains
View	Download	0.206	0.237	mitochondrial outer membrane translocase complex	d.109.1	Actin depolymerizing proteins
View	Download	0.204	0.237	mitochondrial outer membrane translocase complex	d.13.1	HIT-like
View	Download	0.204	0.237	mitochondrial outer membrane translocase complex	d.93.1	SH2 domain
View	Download	0.202	0.237	mitochondrial outer membrane translocase complex	g.59.1	Zinc-binding domain of translation initiation factor 2 beta
View	Download	0.202	0.237	mitochondrial outer membrane translocase complex	g.41.5	Rubredoxin-like

Predicted Domain #3

Region A:
Residues: [228-387]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGVSYLTRYV SKKQDWIFSG QLQANGALIA SLWRKVAQNV EAGIETTLQA GMVPITDPLM  60
   61 GTPIGIQPTV EGSTTIGAKY EYRQSVYRGT LDSNGKVACF LERKVLPTLS VLFCGEIDHF 120
  121 KNDTKIGCGL QFETAGNQEL LMLQQGLDAD GNPLQALPQL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits