YRC Public Data Repository - Protein Structure Prediction

Protein:	TPP1
Organism:	Saccharomyces cerevisiae
Length:	238 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPP1.

Description	E-value	Query Range	Subject Range
gi\|190408381 - gi\|190408381\|gb\|EDV11646.1\| polynucleotide 3'-phosphatase [Saccharomyces cerevisiae RM11-1a] gi\|151945856 - gi\|151945856\|gb\|EDN64088.1\| DNA 3' phosphatase [Saccharomyces cerevisiae YJM789] gi\|207342245 - gi\|207342245\|gb\|EDZ70064.1\| YMR156Cp-like protein [Saccharomyces cerevisiae AWRI1631] TPP1 - DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is... TPP1_YEAST - Polynucleotide 3'-phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPP1 PE=3 ...	4.0E-92	[1..238]	[1..238]
TPP1_SACMI - Polynucleotide 3'-phosphatase OS=Saccharomyces mikatae GN=TPP1 PE=3 SV=1	6.0E-92	[1..238]	[8..245]
gi\|8777472 - gi\|8777472\|dbj\|BAA97052.1\| unnamed protein product [Arabidopsis thaliana]	2.0E-49	[26..236]	[593..765]
gi\|162457949, gi... - gi\|162457949\|ref\|NP_001105016.1\| diphosphonucleotide phosphatase 2 [Zea mays], gi\|14285172\|gb\|AAK588...	4.0E-47	[24..236]	[58..230]
CE27135 - polynucleotide kinase 3' phosphatase status:Confirmed UniProt:Q19683 protein_id:CAA91035.2	5.0E-45	[24..236]	[46..211]
gi\|208967098, gi... - gi\|208967098\|dbj\|BAG73563.1\| polynucleotide kinase 3'-phosphatase [synthetic construct], gi\|12399457... PNKP - polynucleotide kinase 3'-phosphatase	6.0E-44	[30..237]	[166..329]
pnk1 - DNA kinase /phosphatase Pnk1 PNK1_SCHPO - Bifunctional polynucleotide phosphatase/kinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...	1.0E-41	[30..238]	[69..222]

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Predicted Domain #1

Region A:
Residues: [1-238]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHKLTILPF LIKFTPKFPQ SIDHDEHGLN VYAFDLDHTI IKPKSPNISF SRSASDWQFI  60
   61 NFNSKKSTLD YLCNIIDNDP TAVIVIFSNQ GGVITVPRTS KSCTKYTNKI LLFLKAIKND 120
  121 ERGETLSHRL WLYAAPKRPK TFAANHSKIT FASLGESYNN DPNIFEKVRK PMTGMVEFFK 180
  181 RDLESAYRVS EQISPIKLNW IYYCGDAAGR KKDFSDSDIK FAENLHVEFK YPEEIFHG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits