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View Structure Prediction Details

Protein: ASI1
Organism: Saccharomyces cerevisiae
Length: 624 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASI1.

Description E-value Query
Range
Subject
Range
ASI1_YEAST - Protein ASI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASI1 PE=1 SV=1
ASI1 - Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of ...
0.0 [1..624] [1..624]
gi|16198151 - gi|16198151|gb|AAL13880.1| LD35285p [Drosophila melanogaster]
6.0E-34 [305..619] [274..605]
gi|14042062 - gi|14042062|dbj|BAB55092.1| unnamed protein product [Homo sapiens]
1.0E-30 [305..620] [593..901]
gi|15218791 - gi|15218791|ref|NP_171836.1| C2 domain-containing protein / GRAM domain-containing protein [Arabidop...
5.0E-30 [300..622] [493..822]
BIR3_MOUSE, BIRC... - Baculoviral IAP repeat-containing protein 3 OS=Mus musculus GN=Birc3 PE=1 SV=1, (O08863) Baculoviral...
4.0E-28 [386..620] [346..600]

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Predicted Domain #1
Region A:
Residues: [1-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSSTSSENV FINSFSYLNQ TSQAVISGNS TFANVINFPY RLGLSFIGAV NLQYEQTVKS  60
   61 EEIPPTLRSV FDTIGFFFSP YAIFCFVIAI VLNRFVVFYA VLNNGSRRTL PLWLSNVFHV 120
  121 SAVVVLAMVS LGPLTLGKDF KILGDPAFAQ EKFLLNIFYA FAYSYCVETI FTIMRNSSPL 180
  181 EGTDYSLFEL SIQFYTMTNN NTKFLDSPDY IIDCSMAILS RILIHLVEIF RLRNYRLLFS 240
  241 TIMNLCHICY LGIRVKQGGW KSLPFSVKFR HFPKLFSVSI ICLSLLIFKL SCLIRW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [297-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPFGKSRNSC ELLQFYPLSR NWKKYLNYTG EEDFSAMATK FALLLCSGTE LMEKGIRREF  60
   61 PAINIPDNVN EKFFISGYLN ELSKPYKENT SISFPKKNSS ILKQRFFLMF PKSIIWIMKK 120
  121 LVGQVFFGFR DNKDEDIPDN DPSKMLKITK TNSLNNSAGH KEDIELELLN TSDDEYSEDY 180
  181 EPSEVESLGD SDEENLEEDS LIFNETRDAL LDLFSSEDNE VHTDYNWIMS TSRILQQKLL 240
  241 SDKTLTRASI LDTKLSEVDE TFGTESDFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.09691
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [566-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSCAVCKVNE RNTVLWPCRC FAICEDCRIS LGLRGFSTCV CCRSKVHGYC KVHPVSDSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.045757
Match: 1fbvA_
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [560-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TESDFDLSCA VCKVNERNTV LWPCRCFAIC EDCRISLGLR GFSTCVCCRS KVHGYCKVHP  60
   61 VSDSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1fbvA
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle