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View Structure Prediction Details

Protein: MYO5
Organism: Saccharomyces cerevisiae
Length: 1219 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MYO5.

Description E-value Query
Range
Subject
Range
gi|60654463 - gi|60654463|gb|AAX29922.1| myosin IF [synthetic construct]
1319.0 [0..23] [1145..4]
MYO1F - myosin IF
gi|123980364, gi... - gi|157928118|gb|ABW03355.1| myosin IF [synthetic construct], gi|123980364|gb|ABM82011.1| myosin IF [...
1319.0 [0..23] [1145..4]
gi|157821107, gi... - gi|62651832|ref|XP_234942.3| PREDICTED: similar to myosin IF [Rattus norvegicus], gi|157821107|ref|N...
1313.0 [0..23] [1145..4]
gi|27502097, gi|... - gi|27502097|gb|AAO17382.1| myosin-1F-like protein [Mus musculus], gi|255069756|ref|NP_444444.2| myos...
1311.0 [0..23] [1145..4]
gi|345650, gi|65... - gi|65324|emb|CAA49850.1| brush border myosin IB [Gallus gallus], gi|45383938|ref|NP_990585.1| myosin...
1306.0 [0..23] [1145..4]

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Predicted Domain #1
Region A:
Residues: [1-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAILKRGARK KVHQEPAKRS ANIKKATFDS SKKKEVGVSD LTLLSKISDE AINENLKKRF  60
   61 LNATIYTYIG HVLISVNPFR DLGIYTDAVM NEYKGKNRLE VPPHVFAIAE SMYYNMKSYN 120
  121 ENQCVIISGE SGAGKTEAAK RIMQYIAAAS STHTESIGKI KDMVLATNPL LESFGCAKTL 180
  181 RNNNSSRHGK YLEIKFNNQF EPCAGNITNY LLEKQRVVSQ IKNERNFHIF YQFTKGASDA 240
  241 YRQTFGVQKP EQYVYTAAAG CISAETIDDL QDYQETLKAM RVIGLGQEEQ DQIFRMLAAI 300
  301 LWIGNVSFIE NEEGNAQVRD TSVTDFVAYL LQIDSQLLIK SLVERIMETN HGMKRGSVYH 360
  361 VPLNIVQADA VRDALAKAIY NNLFDWIVSR VNKSLQAFPG AEKSIGILDI YGFEIFEHNS 420
  421 FEQICINYVN EKLQQIFIQL TLKSEQETYE REKIQWTPIK YFDNKVVCDL IEARRPPGIF 480
  481 AAMNDSVATA HADSNAADQA FAQRLNLFTT NPHFDLRSNK FVIKHYAGDV TYDIDGITDK 540
  541 NKDQLQKDLV ELIGTTTNTF LATIFPDTVD RESKRRPPTA GDKIIKSAND LVETLSKAQP 600
  601 SYIRTIKPNE TKSPNDYDDR QVLHQIKYLG LQENVRIRRA GF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2660.0
Match: 1lkxA
Description: Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [643-714]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYRQVFEKFV ERFYLLSPHC SYAGDYTWQG DTLDAVKYIL QDSSIPQQEY QLGVTSVFIK  60
   61 TPETLFALEH MR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2660.0
Match: 1lkxA
Description: Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [715-768]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRYWHNMAAR IQRAWRRFLQ RRIDAATKIQ RTIRERKEGN KYEKLRDYGT KVLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1wdcA
Description: SCALLOP MYOSIN REGULATORY DOMAIN
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [769-842]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRKERRSMSL LGYRAFMGDY LSCNESKSKG AYIKRQVSIK EKVIFSIHGE ALHTKFGRSA  60
   61 QRLKKTFLLT PTTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [843-905]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YIVGQTLVQN AMTYTQDYKI DVRNIQAVSL TNLQDDWVAI KLASSGQPDP LINTYFKTEL  60
   61 ITH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [906-957]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKRLNDKIQI KIGSAIEYQK KPGKLHSVKC QINESAPKYG DIYKSSTISV RR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [958-1070]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNPPNSQVHK KPRKKSSISS GYHASSSQAT RRPVSIAAAQ HVPTAPASRH SKKPAPPPPG  60
   61 MQNKAATRRS VPNPASTLTA SQSNARPSPP TAATRATPAA TPAAAAMGSG RQA

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 8.21
Match:
Description: No description for 1ldvA was found.

Predicted Domain #8
Region A:
Residues: [1071-1167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIPPPPPPPP PSSKPKEPMF EAAYDFPGSG SPSELPLKKG DVIYITREEP SGWSLGKLLD  60
   61 GSKEGWVPTA YMKPHSGNNN IPTPPQNRDV PKPVLNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.30103
Match: 1awjA
Description: INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted Domain #9
Region A:
Residues: [1168-1219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQHDNTSANV IPAAAQASLG DGLANALAAR ANKMRLESDD EEANEDEEED DW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle