YRC Public Data Repository - Protein Structure Prediction

Protein:	YMR084W
Organism:	Saccharomyces cerevisiae
Length:	262 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR084W.

Description	E-value	Query Range	Subject Range
GLMS_HAEIN - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Haemophilus influenzae GN=glmS P... GLMS_HAEIN - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Haemophilus influenzae (strain ATC...	2.0E-65	[1..262]	[1..237]
GLMS_PYRAB - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Pyrococcus abyssi GN=glmS PE=3 S... GLMS_PYRAB - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Pyrococcus abyssi (strain GE5 / Or...	1.0E-64	[1..251]	[1..229]
YMR084W - Putative protein of unknown function; YMR084W and adjacent ORF YMR085W are merged in related strains YM084_YEAST - Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Saccharomyces cerevisiae ...	4.0E-64	[1..262]	[1..262]
gi\|25287308 - pir\|\|G91212 hypothetical protein ECs4671 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|15833925, gi\|... - gi\|15833925\|ref\|NP_312698.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli O157:H7], gi\|... gi\|15833925, gi\|... - gi\|15833925\|ref\|NP_312698.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia coli O1...	9.0E-64	[1..244]	[1..221]
gi\|83588406, gi\|... - gi\|83588406\|ref\|ZP_00927030.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|157080617, gi... - gi\|75188487\|ref\|ZP_00701754.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|157068890, gi... - gi\|75197625\|ref\|ZP_00707695.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|75210661, gi\|... - gi\|75210661\|ref\|ZP_00710802.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... EG10382 - L-glutamine:D-fructose-6-phosphate aminotransferase / Glucosamine-6-phosphate synthase; glucosamine-... gi\|191165793, gi... - gi\|75230998\|ref\|ZP_00717433.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|192957549, gi... - gi\|75236461\|ref\|ZP_00720557.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|193063823, gi... - gi\|75258268\|ref\|ZP_00729716.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... GLMS_ECOLI - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (Hexosephosphate amin... gi\|85676309, gi\|... - gi\|89110278\|ref\|AP_004058.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia coli s... gi\|169757162, gi... - gi\|170022234\|ref\|YP_001727188.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|209921210, gi... - gi\|209921210\|ref\|YP_002295294.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|238861652, gi... - gi\|238902820\|ref\|YP_002928616.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia co... gi\|218354187, gi... - gi\|218697455\|ref\|YP_002405122.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|242379267, gi... - gi\|251786994\|ref\|YP_003001298.1\| hypothetical protein B21_03557 [Escherichia coli BL21], gi\|24237926... gi\|254290431, gi... - gi\|254290431\|ref\|YP_003056179.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli BL21(DE3)... gi\|226838913, gi... - gi\|254038948\|ref\|ZP_04873000.1\| glutamine-fructose-6-phosphate transaminase [Escherichia sp. 1_1_43]... gi\|254163681, gi... - gi\|254163681\|ref\|YP_003046789.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli B str. RE... EG10382 - L-glutamine:D-fructose-6-phosphate aminotransferase / Glucosamine-6-phosphate synthase; glucosamine-... gi\|124530057, gi... - gi\|124530057\|ref\|ZP_01700840.1\| glucosamine--fructose-6-phosphate aminotransferase, isomerizing [Esc...	1.0E-63	[1..244]	[1..221]
gi\|209158986, gi... - gi\|209397586\|ref\|YP_002273257.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:... gi\|217321769, gi... - gi\|217325548\|ref\|ZP_03441632.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... gi\|25287310, gi\|... - pir\|\|H86058 hypothetical protein glmS [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|195936356 - gi\|195936356\|ref\|ZP_03081738.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli O157:H7 st... gi\|208806513, gi... - gi\|208806513\|ref\|ZP_03248850.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... gi\|15804329, gi\|... - gi\|15804329\|ref\|NP_290368.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli O157:H7 EDL93... gi\|208734215, gi... - gi\|208812938\|ref\|ZP_03254267.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... GLMS_ECO57 - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Escherichia coli O157:H7 GN=glmS P... gi\|208739668, gi... - gi\|208819545\|ref\|ZP_03259865.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... gi\|187771681, gi... - gi\|187771681\|gb\|EDU35525.1\| glutamine-fructose-6-phosphate transaminase (isomerizing) [Escherichia c... gi\|189002421, gi... - gi\|189002421\|gb\|EDU71407.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|189373264, gi... - gi\|189373264\|gb\|EDU91680.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|189378781, gi... - gi\|189378781\|gb\|EDU97197.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|168748541, gi... - gi\|188016915\|gb\|EDU55037.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|254795735, gi... - gi\|254795735\|ref\|YP_003080572.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia co... gi\|168753631, gi... - gi\|189359185\|gb\|EDU77604.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|168759929, gi... - gi\|189369471\|gb\|EDU87887.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|168766229, gi... - gi\|189364600\|gb\|EDU83019.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st...	1.0E-63	[1..244]	[1..221]
gi\|43268 - gi\|43268\|emb\|CAA25785.1\| unnamed protein product [Escherichia coli]	1.0E-63	[1..244]	[1..221]
GLMS_SALTY - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Salmonella typhimurium (strain LT2... GLMS_SALTY - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Salmonella typhimurium GN=glmS P... lcl\|NC_016856.1_... - [gene=glmS] [protein=D-fructose-6-phosphate amidotransferase] [protein_id=YP_005240128.1] [location=... GLMS_SALTY - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Salmonella typhimurium GN=glmS P... gi\|205327082, gi... - gi\|205327082\|gb\|EDZ13846.1\| glutamine-fructose-6-phosphate transaminase [Salmonella enterica subsp. ...	4.0E-63	[1..244]	[1..221]
GLMS_SALTI - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Salmonella typhi GN=glmS PE=3 SV... gi\|214001320 - gi\|214001320\|ref\|ZP_03412055.1\| D-fructose-6-phosphate amidotransferase [Salmonella enterica subsp. ... GLMS_SALTI - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Salmonella typhi GN=glmS PE=3 SV=3 gi\|213427474 - gi\|213427474\|ref\|ZP_03360224.1\| D-fructose-6-phosphate amidotransferase [Salmonella enterica subsp. ... gi\|213052673 - gi\|213052673\|ref\|ZP_03345551.1\| D-fructose-6-phosphate amidotransferase [Salmonella enterica subsp. ... gi\|29143953, gi\|... - gi\|29143953\|ref\|NP_807295.1\| D-fructose-6-phosphate amidotransferase [Salmonella enterica subsp. ent... gi\|16762465 - gi\|16762465\|ref\|NP_458082.1\| D-fructose-6-phosphate amidotransferase [Salmonella enterica subsp. ent...	5.0E-63	[1..244]	[1..221]

Back

Predicted Domain #1

Region A:
Residues: [1-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIFGYCNF LIEKTRGEII DTLIEGLQAL EYKEYDSSGI SIQGDELESL NIYKQTGKIS  60
   61 SLKEEIDLYN LNKNLPFISH CGIAHTRRAT HGGLRRANCH PHNSDPSNEF VVVHNGVITN 120
  121 FANLKALLMA KGYVFKSDTD TECIPKLYKH IYDTSIELGY NLDFHVLTNL VLKELEGSYG 180
  181 LLCTSSHFPD EVVAARKGSP LVIGVKGKTD MDVNFVEVEY LDQEEDYLKL NTQTKSSGNV 240
  241 LAAAPVKYNT CLRKSPPFVH NT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	343.30103
Match:	1jxaA_
Description:	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.430202686180205	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: