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View Structure Prediction Details

Protein: YMR018W
Organism: Saccharomyces cerevisiae
Length: 514 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR018W.

Description E-value Query
Range
Subject
Range
gi|47222947 - gi|47222947|emb|CAF99103.1| unnamed protein product [Tetraodon nigroviridis]
290.0 [0..4] [496..56]
gi|76659271 - gi|76659271|ref|XP_884992.1| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 7 [...
280.0 [0..9] [490..49]
gi|56967372, gi|... - gi|62821820|ref|NP_001017359.1| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...
280.0 [0..9] [490..49]
gi|91079875 - gi|91079875|ref|XP_967579.1| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]
278.0 [0..21] [472..164]
gi|27499606 - gi|27499606|gb|AAO17363.1| O-linked GlcNAc transferase [Mus musculus]
278.0 [0..9] [493..49]
gi|115936542, gi... - gi|115936542|ref|XP_001177116.1| PREDICTED: similar to UDP-N-acetylglucosaminyltransferase [Strongyl...
277.0 [0..21] [490..17]
gi|74007684 - gi|74007684|ref|XP_858918.1| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 11 ...
277.0 [0..9] [490..49]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEVTCSITG DNPIHKINNG LGLKWNNLGK FSDFQTNDSA ARDARTIDYI FTNCQTGSSI  60
   61 GKIDFRAALP ADKSQHSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.609 N/A N/A b.55.1 PH domain-like
View Download 0.598 N/A N/A b.55.1 PH domain-like
View Download 0.598 N/A N/A b.55.1 PH domain-like
View Download 0.557 N/A N/A d.145.1 FAD-binding domain
View Download 0.557 N/A N/A b.55.1 PH domain-like
View Download 0.557 N/A N/A b.55.1 PH domain-like
View Download 0.553 N/A N/A b.55.1 PH domain-like
View Download 0.553 N/A N/A b.55.1 PH domain-like
View Download 0.552 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.520 N/A N/A b.3.2 Carboxypeptidase D, a regulatory domain

Predicted Domain #2
Region A:
Residues: [79-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEKEFSRLE NQWSKEFSCF PKNKNADVTK PSRNKHEKRS ANLHNRYFAQ YYSTAYQQNR  60
   61 IYPCRISYNE HSSVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.636 a.2.7 tRNA-binding arm
View Download 0.636 a.2.7 tRNA-binding arm
View Download 0.615 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.423 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.423 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.423 a.142.1 PTS-regulatory domain, PRD
View Download 0.423 a.142.1 PTS-regulatory domain, PRD
View Download 0.417 a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.403 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

Predicted Domain #3
Region A:
Residues: [154-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGWEFQFKSI ENQLLNELKI ENNVEEKTVG YEYVAEYEET IDFMHMLSSV PQTYQFLKSN  60
   61 IYITERDPYK IGCVLMDNGS NLNEVVMAFE AAISQDPSHI NAWLKLGIVN FENESESNGE 120
  121 LALRNCLNLD PNNTIALENL AIHHINQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 315.594777
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [302-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NESESLKLFH KWILSKFSKV FQPSAGENKD SINKIPKKAH LAHILESLLN MGIEKKDQYD  60
   61 IYSVLSILYY SDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 315.594777
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [375-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIKQSQKCLE FLLLEKPNNG TIWNRYGAIL ANTKSYHSAI NAYNKCKQLR PNFTRVRYNL  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 315.594777
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [435-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIAYMNKGDY VKASKMLIEV ILLRSKGYEH NKAKMQNKFM QNLKNALIAS KNFDSLDLIN  60
   61 GSHNTESLIS TLKAIYNKMD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 315.594777
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle