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View Structure Prediction Details

Protein: MVP1
Organism: Saccharomyces cerevisiae
Length: 511 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MVP1.

Description E-value Query
Range
Subject
Range
gi|562121 - gi|562121|gb|AAA67884.1| Mvp1p
0.0 [1..511] [1..511]
gi|12248793 - gi|12248793|dbj|BAB20283.1| sorting nexin 1 [Mus musculus]
2.0E-77 [4..506] [18..520]
SNX1_RAT - Sorting nexin-1 OS=Rattus norvegicus GN=Snx1 PE=1 SV=1
3.0E-77 [4..506] [18..521]
SNX9 - sorting nexin 9
gi|114609935 - gi|114609935|ref|XP_001144722.1| PREDICTED: sorting nexin 9 isoform 5 [Pan troglodytes]
5.0E-76 [6..467] [104..592]
gi|18149005 - gi|18149005|dbj|BAB83537.1| sorting nexin 1 [Macaca fascicularis]
6.0E-67 [48..506] [6..473]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNYEGSDPW NTSSNAWTKD DDHVVSTTNS EPSLNGISGE FNTLNFSTPL DTNEEDTGFL  60
   61 PTNDVLEESI WDDSRNPLGA TGMS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [85-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTPNIAANET VIDKNDARDQ NIEESEADLL DWTNNVRKTY RPLDADIIII EEIPEREGLL  60
   61 FKHANYLVKH LIALPSTSPS EERTVVRRYS DFLWLREILL KRYPFRMIPE LPPKRIGSQN 120
  121 ADQLFLKKRR IGLSRFINLV MKHPKLSNDD LVLTFLTVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.154902
Match: 1h6hA_
Description: p40phox NADPH oxidase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [244-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDLTSWRKQA TYDTSNEFAD KKISQEFMKM WKKEFAEQWN QAASCIDTSM ELWYRITLLL  60
   61 ERHE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [431-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYDRIKKIIQ KDRRSIIEQS NRAWLIRQCI LEEFTIFQET QFLITRAFQD WAKLNSNHAG  60
   61 LKLNEWEKLV TSIMDMPISR E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1dg3A_
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [308-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRIMQMVHER NFFETLVDNF SEVTPKLYPV QQNDTILDIN NNLSIIKKHL ETTSSICKQE  60
   61 TEEISGTLSP KFKIFTDILL SLRSLFERYK IMAANNVVEL QRHVELNKEK LESMKGKPDV 120
  121 SGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1dg3A_
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle