YRC Public Data Repository - Protein Structure Prediction

Protein:	YML131W
Organism:	Saccharomyces cerevisiae
Length:	365 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YML131W.

Description	E-value	Query Range	Subject Range
gi\|7248741 - gi\|7248741\|gb\|AAF43645.1\|AF218309_1 alcohol dehydrogenase isozyme 3; Adh3 [Saccharomyces kluyveri]	2.0E-83	[8..363]	[22..373]
ADH5_SACPS - Alcohol dehydrogenase 5 OS=Saccharomyces pastorianus GN=ADH5 PE=3 SV=1 gi\|190408701 - gi\|190408701\|gb\|EDV11966.1\| alcohol dehydrogenase isoenzyme V [Saccharomyces cerevisiae RM11-1a] ADH5 - Alcohol dehydrogenase isoenzyme V; involved in ethanol production ADH5_YEAST - Alcohol dehydrogenase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH5 PE=1 SV=1 gi\|151946534 - gi\|151946534\|gb\|EDN64756.1\| alcohol dehydrogenase isoenzyme V [Saccharomyces cerevisiae YJM789]	5.0E-82	[9..363]	[1..351]
ADH3_KLULA - Alcohol dehydrogenase 3, mitochondrial OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70... ADH3_KLULA - Alcohol dehydrogenase 3, mitochondrial OS=Kluyveromyces lactis GN=ADH3 PE=3 SV=2	2.0E-81	[11..362]	[26..373]
gi\|15234529, gi\|... - pir\|\|T05166 quinone reductase homolog F18E5.200 - Arabidopsis thaliana, gi\|7268955\|emb\|CAB81265.1\| p...	3.0E-81	[18..360]	[1..324]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	7.0E-80	[17..359]	[1..322]
ADH1_KLUMA - Alcohol dehydrogenase 1 OS=Kluyveromyces marxianus GN=ADH1 PE=3 SV=1	1.0E-79	[14..363]	[3..348]

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Predicted Domain #1

Region A:
Residues: [1-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLAKQWVLK NLPTPGEPFN FHFHDPACTF ELIEKELSSE QLKDGELLLE TTYLSNDPAQ  60
   61 KFWISSMDKN YAKGVQPGEI IPARGIGKVL ASRNKAFSPG DYVSAVTGWT THAIISQENV 120
  121 QGLRKLDKNK VGKLWWYLSV LG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [325-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKSATLEDGT GDKFKNVPLI WKGLFSGVNK GKLITKVNNE E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.522879
Match:	1qorA_
Description:	Quinone oxidoreductase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [143-324]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTSLTAYFIF FTYAQLQERE EDYGKVYLIS GAAGAVGTVC IQLALNVFKA SKVIAIAGGP  60
   61 EKVAFVESFG DNVVGVDYKD PSFKQKLIEA AGGENTVDYF IDNVGSNVLE AGVLLLKQRA 120
  121 MLIACGAISA YNDPSKFVFK GYSFILTKRL VVKGVLVTDN IDDFPKALDK LGSLVKHGKI 180
  181 DL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.522879
Match:	1qorA_
Description:	Quinone oxidoreductase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits