YRC Public Data Repository - Protein Structure Prediction

Protein:	TAF8
Organism:	Saccharomyces cerevisiae
Length:	510 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF8.

Description	E-value	Query Range	Subject Range
TAF8_YEAST - Transcription initiation factor TFIID subunit 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2... TAF8 - TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation	0.0	[1..510]	[1..510]
TAF8_ARATH - Transcription initiation factor TFIID subunit 8 OS=Arabidopsis thaliana GN=TAF8 PE=1 SV=1	5.0E-88	[5..302]	[3..290]
gi\|20070378, gi\|... - gi\|20070378\|ref\|NP_612639.1\| taube nuss [Homo sapiens], gi\|16553063\|dbj\|BAB71460.1\| unnamed protein ...	5.0E-58	[9..237]	[12..204]
TAF8_MOUSE - Transcription initiation factor TFIID subunit 8 OS=Mus musculus GN=Taf8 PE=2 SV=1	1.0E-56	[9..237]	[10..202]
taf-8 - status:Partially_confirmed UniProt:Q8WQ97 protein_id:CAD18882.1	1.0E-53	[2..221]	[44..230]
gi\|17946385 - gi\|17946385\|gb\|AAL49226.1\| RE65343p [Drosophila melanogaster]	4.0E-50	[30..238]	[15..187]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSKTSESGT GTQSTIVQLR NLPDLTEISH LEIDAPVVEI LKKTVLFQLN SLNICISNFA  60
   61 LDELVNLVTV QMDGMFRNLH NLTLLQRRSQ ASQADLKLLL REFNLDAPSL YQQFQASEFI 120
  121 KSKHSTEYEK LMSWSSLAAL PHNEEDEEDE LNNIEEQQNE INVLLPPSNP LEKQIPSWLP 180
  181 NFPPDHTYKF TPEFNHPITD LKTIKKEIVK ESQESEKALL NLNKSLSHIS SASNTPQPPG 240
  241 LDDEDAIEQQ LEIWGNALEE RKPT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [265-510]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITEKSFNENN IEQYAKYRVE LARERVTKFE VNQLKRTKNP FLKISETLYL PESPHQSHKT  60
   61 IQKTIELQFR KSMTLFMHNL PKVQKLKKEK IRMAKEERAK SLKRRQEELI SQRTKREQDE 120
  121 GHDLELLLNN EHARDAADDT TTPNALNNST IVINTNAEDE DDDINLFGIL GSSEDENEMS 180
  181 SMPAENLVAE SEPPTMTAQD TTNTTPVAHN TTNIDATTSH SPHSTPNENA PTSPPADIAT 240
  241 DHDITM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [192-510]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEFNHPITDL KTIKKEIVKE SQESEKALLN LNKSLSHISS ASNTPQPPGL DDEDAIEQQL  60
   61 EIWGNALEER KPTITEKSFN ENNIEQYAKY RVELARERVT KFEVNQLKRT KNPFLKISET 120
  121 LYLPESPHQS HKTIQKTIEL QFRKSMTLFM HNLPKVQKLK KEKIRMAKEE RAKSLKRRQE 180
  181 ELISQRTKRE QDEGHDLELL LNNEHARDAA DDTTTPNALN NSTIVINTNA EDEDDDINLF 240
  241 GILGSSEDEN EMSSMPAENL VAESEPPTMT AQDTTNTTPV AHNTTNIDAT TSHSPHSTPN 300
  301 ENAPTSPPAD IATDHDITM

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.26
Match:	2i1jA
Description:	No description for 2i1jA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits