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View Structure Prediction Details

Protein: TEM1
Organism: Saccharomyces cerevisiae
Length: 245 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TEM1.

Description E-value Query
Range
Subject
Range
ARA5_ARATH - Ras-related protein ARA-5 - Arabidopsis thaliana (Mouse-ear cress)
6.0E-85 [2..219] [45..258]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-84 [14..218] [2..202]
gi|1370166 - gi|1370166|emb|CAA98160.1| RAB1C [Lotus japonicus]
6.0E-84 [14..218] [2..202]
gi|1616614 - gi|1616614|emb|CAA69701.1| small GTP-binding protein [Nicotiana plumbaginifolia]
1.0E-83 [14..219] [2..203]
RIC1_ORYSA - (P40392) Ras-related protein RIC1
2.0E-83 [14..218] [2..202]
gi|1381678 - gi|1381678|gb|AAB97115.1| small GTP-binding protein [Glycine max]
5.0E-83 [14..218] [2..202]
gi|7643790 - gi|7643790|gb|AAF65510.1| small GTP-binding protein [Capsicum annuum]
5.0E-83 [14..219] [2..203]

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Predicted Domain #1
Region A:
Residues: [1-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPSTGANN SIPAVRNQVE VQVGLVGDAQ VGKTSLMVKY VQNIYDKEYT QTLGVNFLKR  60
   61 KVSIRSTDII FSIMDLGGQR EFINMLPIAT VGSSVIIFLF DLTRPETLSS IKEWYRQAYG 120
  121 LNDSAIPILV GTKYDLLIDL DPEYQEQISR TSMKYAQVMN APLIFCSTAK SINIQKIFKI 180
  181 ALAKIFNLTL TIPEINEIGD PLLIYKHLGG QQHRHHNKSQ DRKSHNIRKP SSSPSSKAPS 240
  241 PGVNT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 208.522879
Match: 1g17A_
Description: Rab-related protein Sec4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 4.51968578934603 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.74389108884083 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
pyrophosphatase activity 2.67097555143215 bayes_pls_golite062009
hydrolase activity 2.65461298232951 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.65161658635465 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.64849912301318 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
microfilament motor activity 2.51786963027655 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
primary active transmembrane transporter activity 2.39629638016861 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.39600931083427 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.36051733655256 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.35906629925754 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.35679406876731 bayes_pls_golite062009
actin binding 2.2973522188675 bayes_pls_golite062009
ATPase activity 2.2625504298178 bayes_pls_golite062009
ATPase activity, coupled 2.24901251684901 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
nucleic acid binding 1.84541587592638 bayes_pls_golite062009
substrate-specific transporter activity 1.65609907941094 bayes_pls_golite062009
GTPase activity 1.6309422514633 bayes_pls_golite062009
DNA binding 1.48341220422804 bayes_pls_golite062009
plus-end-directed microtubule motor activity 1.38366133153678 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.3182108176243 bayes_pls_golite062009
transcription regulator activity 1.30136714640988 bayes_pls_golite062009
actin filament binding 1.28204719195916 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
actin-dependent ATPase activity 0.92105578610354 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
ion transmembrane transporter activity 0.704934361725919 bayes_pls_golite062009
signal transducer activity 0.683309012097319 bayes_pls_golite062009
molecular transducer activity 0.683309012097319 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
transcription activator activity 0.374651542607188 bayes_pls_golite062009
transcription factor activity 0.341088753451767 bayes_pls_golite062009
cation transmembrane transporter activity 0.282397764628576 bayes_pls_golite062009
protein transporter activity 0.217249710833262 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
sequence-specific DNA binding 0.106147926780353 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle