YRC Public Data Repository - Protein Structure Prediction

Protein:	SPC2
Organism:	Saccharomyces cerevisiae
Length:	178 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPC2.

Description	E-value	Query Range	Subject Range
SPCS2_CANLF - Signal peptidase complex subunit 2 OS=Canis lupus familiaris GN=SPCS2 PE=1 SV=1	7.0E-62	[6..176]	[47..223]
SPCS2 - signal peptidase complex subunit 2 homolog (S. cerevisiae)	2.0E-61	[6..176]	[47..223]
SPCS2_MOUSE - Signal peptidase complex subunit 2 OS=Mus musculus GN=Spcs2 PE=1 SV=1	2.0E-60	[6..176]	[47..223]
gi\|220954328, gi... - gi\|220954328\|gb\|ACL89707.1\| Spase25-PA [synthetic construct], gi\|220944448\|gb\|ACL84767.1\| Spase25-PA... FBpp0309254, Spa... - The gene Spase 25-subunit is referred to in FlyBase by the symbol Dmel\Spase25 (CG1751, FBgn0030306)...	2.0E-54	[6..176]	[16..190]
gi\|151946110 - gi\|151946110\|gb\|EDN64341.1\| signal peptidase complex subunit [Saccharomyces cerevisiae YJM789] SPC2_YEAST - Signal peptidase complex subunit SPC2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SP... gi\|207342527 - gi\|207342527\|gb\|EDZ70268.1\| YML055Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190408189 - gi\|190408189\|gb\|EDV11454.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] SPC2 - Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-ter...	4.0E-53	[1..178]	[1..178]
CE20214 - status:Confirmed UniProt:Q9XWW1 protein_id:CAA21529.1	3.0E-51	[4..172]	[6..175]
SPCS2_ARATH - Probable signal peptidase complex subunit 2 OS=Arabidopsis thaliana GN=At2g39960 PE=2 SV=1	2.0E-48	[3..168]	[12..179]
SPC2_SCHPO - Signal peptidase complex subunit spc2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spc2... SPAC1071.04c - signal peptidase subunit	1.0E-39	[9..167]	[3..160]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAKPINVY SIPELNQALD EALPSVFARL NYERSYALLD AKLYIGYSIA VVAGLSFFLD  60
   61 KKFERDQIVT YQKLLVGAYF VLSLLFWYFS RFIEKGTVYV GKRRGTKEEI YVKTKFEKNE 120
  121 PLYLVELVQK KKGENSKKEL KAKLEVNKVF NESGYLQNDA YFKWFSEQHN VLDTKKNE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits