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View Structure Prediction Details

Protein: APT1
Organism: Saccharomyces cerevisiae
Length: 187 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APT1.

Description E-value Query
Range
Subject
Range
APT_MASHI - Adenine phosphoribosyltransferase OS=Mastomys hildebrandtii GN=APRT PE=3 SV=1
3.0E-43 [1..181] [1..180]
APT_RAT - Adenine phosphoribosyltransferase OS=Rattus norvegicus GN=Aprt PE=1 SV=1
5.0E-43 [1..180] [1..179]
APT_CRIGR - Adenine phosphoribosyltransferase OS=Cricetulus griseus GN=APRT PE=3 SV=2
APT_CRILO - (P47952) Adenine phosphoribosyltransferase (EC 2.4.2.7) (APRT)
6.0E-43 [3..180] [2..179]
APT_MUSPA - Adenine phosphoribosyltransferase OS=Mus pahari GN=Aprt PE=3 SV=1
6.0E-43 [1..181] [1..180]
APT_STOLO - Adenine phosphoribosyltransferase OS=Stochomys longicaudatus GN=APRT PE=3 SV=1
6.0E-43 [1..180] [1..179]
APT_MUSSI - Adenine phosphoribosyltransferase OS=Mus spicilegus GN=Aprt PE=3 SV=1
APT_MOUSE - Adenine phosphoribosyltransferase OS=Mus musculus GN=Aprt PE=1 SV=2
8.0E-43 [1..181] [1..180]
APT_DIPCP - Adenine phosphoribosyltransferase OS=Dipodillus campestris GN=APRT PE=3 SV=1
1.0E-42 [3..180] [2..179]
APT_MOUSE - Adenine phosphoribosyltransferase OS=Mus musculus GN=Aprt PE=2 SV=1
2.0E-42 [1..181] [1..180]
APT1_WHEAT - Adenine phosphoribosyltransferase 1 OS=Triticum aestivum GN=APT1 PE=2 SV=1
2.0E-42 [1..182] [1..179]
gi|9711921 - gi|9711921|dbj|BAB08003.1| Adenine phosphoribosyltransferase [Hordeum vulgare subsp. vulgare]
6.0E-42 [1..182] [1..179]

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Predicted Domain #1
Region A:
Residues: [1-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIASYAQEL KLALHQYPNF PSEGILFEDF LPIFRNPGLF QKLIDAFKLH LEEAFPEVKI  60
   61 DYIVGLESRG FLFGPTLALA LGVGFVPVRK AGKLPGECFK ATYEKEYGSD LFEIQKNAIP 120
  121 AGSNVIIVDD IIATGGSAAA AGELVEQLEA NLLEYNFVME LDFLKGRSKL NAPVFTLLNA 180
  181 QKEALKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 932.9794
Match: 1g2pA_
Description: Adenine PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
adenine phosphoribosyltransferase activity 4.07252508868782 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.91023158228049 bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity 3.89356447922614 bayes_pls_golite062009
transferase activity 3.88709784255536 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.53679639481311 bayes_pls_golite062009
uracil phosphoribosyltransferase activity 2.36237864658341 bayes_pls_golite062009
catalytic activity 2.30431811394775 bayes_pls_golite062009
amidophosphoribosyltransferase activity 1.6596316647688 bayes_pls_golite062009
ribose phosphate diphosphokinase activity 1.51875493459374 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.45489477082258 bayes_pls_golite062009
purine binding 1.3774977535406 bayes_pls_golite062009
nucleobase binding 1.28671115202467 bayes_pls_golite062009
transcription regulator activity 1.09798789282825 bayes_pls_golite062009
nucleic acid binding 1.07284130528063 bayes_pls_golite062009
DNA binding 0.854593555814443 bayes_pls_golite062009
adenine binding 0.817887117933035 bayes_pls_golite062009
diphosphotransferase activity 0.749909396904601 bayes_pls_golite062009
binding 0.691442295634288 bayes_pls_golite062009
transcription factor activity 0.339219342075596 bayes_pls_golite062009
orotate phosphoribosyltransferase activity 0.148898393751978 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle